Abstract: Provided are antibodies specific for human QSOX1 and methods of using these antibodies or antigen binding regions thereof in assays to detect QSOX1, to inhibit QSOX1, for use in other assay systems, and for use in treating cancer.

Abstract: Compounds and methods involving inhibition of the enzymatic activity of QSOX1. The compounds and methods can be used in treatment of neoplastic cells, for example, to suppress tumor growth and invasion in a variety of cancers, including but not limited to myeloma and cancers of the breast, kidney, and pancreas.

Abstract: Compounds and methods involving inhibition of the enzymatic activity of QSOX1 (FIG. 13). The compounds and methods can be used in treatment of neoplastic cells, for example, to suppress tumor growth and invasion in a variety of cancers, including but not limited to myeloma and cancers of the breast, kidney, and pancreas.

Abstract: Compounds and methods involving inhibition of the enzymatic activity of QSOX1 (FIG. 13). The compounds and methods can be used in treatment of neoplastic cells, for example, to suppress tumor growth and invasion in a variety of cancers, including but not limited to myeloma and cancers of the breast, kidney, and pancreas.

Abstract: A fastener detection system detects a fastener striking an anvil. The fastener detection system comprises a first anvil section having a first conductive work surface that receives a first leg of the fastener during a fastening operation, and a second anvil section having a second conductive work surface that receives a second leg of the fastener during the fastening operation. The second conductive work surface is electrically isolated from the first conductive work surface of the first anvil section. A first conductor electrically couples the first conductive work surface to a detection circuit, and a second conductor electrically couples the second conductive work surface to the detection circuit. The detection circuit identifies that the fastening operation has occurred by electrically sensing continuity between the first conductive work surface of the first anvil section and the second conductive work surface of the second anvil section.