Abstract: New platform technologies to actuate and sense force propagation in real-time for large sheets of cells are provided. In certain embodiments the platform comprises a device for the measurement of mechanical properties of cells or other moieties, where device comprises a transparent elastic or viscoelastic polymer substrate disposed on a rigid transparent surface; and a plurality of micromirrors disposed on or in said polymer substrate, wherein the reflective surfaces of the micromirrors are oriented substantially parallel to the surface of said polymer substrate. In certain embodiments the device comprises more than about 1,000,000, or more than about 10,000,000 micromirrors. In certain embodiments the micromirrors comprise a magnetic layer and/or a diffraction grating.

Abstract: The present invention provides a method comprising the steps of: generating a second anchor on the second convolutional feature map by scaling and shifting a first anchor in the ground-truth box; generating a third convolutional feature map by convolving the second convolutional feature map by means of a second convolution; determining whether the overlap ratio between the ground-truth box and a second single anchor is greater than or equal to a reference value; generating a third anchor by scaling and shifting the second anchor having an overlap ratio that is greater than or equal to the reference value; assigning an objectivity score to the third anchor; and presenting the third anchor, which has an objectivity score that is equal to or greater than a reference value, as a proposal on the third convolutional feature map.

Abstract: A processor includes a time counter and a time-resource matrix and provides a method for statically dispatching instructions if the resources are available based on data stored in the time-resource matrix, and wherein execution times for the instructions use a time count from the time counter to specify when the instructions may be provided to an execution pipeline. The execution times are based on fixed latency times of instructions with exception of the load instruction which is based on the data cache hit latency time. A data cache miss causes the load instruction and subsequent dependent instructions to be statically replayed at a later time using the same time count.

Abstract: The system includes an optical resonator, a mount, and a fastener. The optical resonator is comprised of a material with a horizontal plane symmetry. The optical resonator includes a horizontal plane protrusion for mounting. The horizontal plane protrusion includes discrete resonator rotational orientation positions. The mount comprises mounting legs compatible with the horizontal plane symmetry. The mount includes discrete mount rotational orientation positions that correspond to the discrete resonator rotation orientation positions at a plurality of rotational angles. The fastener secures the horizontal plane protrusion of the optical resonator to the mount.

Abstract: The invention relates to a method of generating an induced pluripotent stem cell. The method of the disclosure comprises expressing exogenous nucleic acids encoding the proteins OCT3/4, SOX2, KLF4, LIN28 and L-MYC and the p53-shRNA in a stem cell of the amniotic membrane of the umbilical cord under conditions suitable to reprogram the stem cell, thereby generating the induced pluripotent stem cell. The present invention also refer to an induced pluripotent stem cell population obtainable by the method and an induced pluripotent stem cell population obtained by the method. Further, a pharmaceutical composition comprising the induced pluripotent stem cell of the present invention is concerned. The present invention also relates to a method of differentiating the induced pluripotent stem cell of this invention. In addition, a pharmaceutical composition comprising a differentiated induced pluripotent stem cell obtained by the method is also concerned.

Abstract: The present disclosure relates to a smart and novel electronic hair clipper with a digital taper lever. Particularly, the electronic hair clipper includes a housing, a pair of clipper blades disposed on a top portion of the housing, and a digital taper lever disposed along an upper side portion of the housing near the clipper blades for electronically controlling a taper lever height.

Abstract: An anomaly detection method for detecting an anomaly in an in-vehicle network of an in-vehicle network system including a plurality of electronic control units that transmit and receive messages via the network includes: generating image data of a reception interval between a plurality of messages included in a message sequence in a predetermined period out of a message sequence received from the in-vehicle network, or image data of a transition of a sensor value of the plurality of messages; classifying the image data using a trained CNN according to whether an attack message has been inserted in the predetermined period; and when the attack message has been inserted in the predetermined period, outputting a detection result indicating that an insertion attack which is an insertion of the attack message has been made in the predetermined period.

Abstract: A processor includes a time counter and provides a method for statically dispatching fused instructions with first operation and second operation with preset execution times for forwarding of result data from the first operation to the second operation without writing to a register, and where the preset execution times are based on a time count from the time counter provided to an execution pipeline.

Abstract: An information processing apparatus deletes specific types of characters from each of multiple sentences and generates multiple word strings which do not include the specific types of characters and correspond to the multiple sentences. The information processing apparatus divides the multiple word strings into multiple groups, each including two or more word strings. The information processing apparatus performs, for each of the multiple groups, padding to equalize the number of words among the two or more word strings based on the maximum number of words in the two or more word strings. The information processing apparatus updates, using each of the multiple padded groups, parameter values included in a natural language processing model that calculates an estimate value from a word string input thereto.

Abstract: The present disclosure introduces methods for characterizing iron core carbohydrate colloid drug products, such as iron sucrose drug products. Disclosed methods enable the characterization of the iron core size of the iron core nanoparticles in iron carbohydrates as they exist in the formulation in solution, such as e.g. iron sucrose drug products, and more particularly, the average particle diameter size and size distribution(s) of the iron core nanoparticles. The disclosed methods apply small-angle X-ray scattering (SAXS) in parallel beam transmission geometry, with a sample mounted inside a capillary and centered in the X-ray beam, to iron carbohydrates, such as iron sucrose, in solution without the need to modify the sample, such as to remove unbound carbohydrates, dilute, or dry the sample, to accurately characterize the average iron core particle diameter size of the iron core nanoparticles.

Abstract: A method includes obtaining multiple image frames. The method also includes selecting, using at least one processing device of an electronic device, an asymmetrical image pair from the multiple image frames. The asymmetrical image pair includes a first image frame and a second image frame, where the first image frame has a shorter exposure than the second image frame. The method further includes identifying, using the at least one processing device, one or more features based on the asymmetrical image pair. The method also includes determining, using the at least one processing device, whether the first image frame contains flicker based on the one or more features. In addition, the method includes enabling or disabling, using the at least one processing device, the first image frame as a reference candidate based on the determination whether the first image frame contains flicker.

Abstract: A system with flexible communication interconnections includes devices and a layer-one switch interconnecting disjoint pairings of communication interfaces. The devices each have at least one communication interface. The layer-one switch has ports, each coupled to a respective one of the communication interfaces, which include the communication interface of each of the devices. For every pairing of a first and different second one of the ports within the disjoint pairings, the layer-one switch is configurable to interconnect bidirectional communications between the respective communication interface for the first port and the respective communication interface for the second port.

Abstract: A processor includes a time counter and provides a method for statically dispatching instructions with preset execution times based on a time count from the time counter provided to an execution pipeline.

Abstract: A processor includes a time counter and a time-resource matrix and provides a method for statically dispatching instructions if the resources are available based on data stored in the time-resource matrix, and wherein execution times for the instructions use a time count from the time counter to specify when the instructions may be provided to an execution pipeline.

Abstract: A multithread processor includes a time counter and a register scoreboard and provides a method for statically dispatching instructions with preset execution times based on a write time of a register in the register scoreboard and the time counter provided to an execution pipeline.

Abstract: A processor includes a time counter and a register scoreboard and operates to statically dispatch instructions with preset execution times based on a write time of a register in the register scoreboard and a time count of the time counter provided to an execution pipeline.

Abstract: Training deep neural networks requires a large amount of labeled training data. Conventionally, labeled training data is generated by gathering real images that are manually labelled which is very time-consuming. Instead of manually labelling a training dataset, domain randomization technique is used generate training data that is automatically labeled. The generated training data may be used to train neural networks for object detection and segmentation (labelling) tasks. In an embodiment, the generated training data includes synthetic input images generated by rendering three-dimensional (3D) objects of interest in a 3D scene. In an embodiment, the generated training data includes synthetic input images generated by rendering 3D objects of interest on a 2D background image. The 3D objects of interest are objects that a neural network is trained to detect and/or label.

Abstract: A machine causes capture of an image that depicts an optically readable code exhibited by a measurement device that corresponds to a scheduled medical procedure. The machine then determines, based on the optically readable code depicted by the captured image, a hardware identifier of a network interface of the measurement device and a location identifier of the measurement device. The machine next identifies the medical procedure based on the location identifier determined based on the optically readable code exhibited by the measurement device. The machine establishes a network connection with the measurement device based on the determined hardware identifier of the network interface of the measurement device. The established network connection may provide access to measurement data generated by the measurement device that corresponds to the scheduled medical procedure identified based on the location identifier of the measurement device.

Abstract: A dispensing device which has a dispensing channel extending between a supply opening and an output opening into the course of which a pump, a selection valve and a dispensing valve are connected. The selection valve is also connected to a pressurised air source. The dispensing device allows a dispensed output of a fluid, wherein a buffer channel portion is filled by the pump in a pump dispensing phase, to which buffer channel portion pressure is applied from the pressurised air source during a pressurised air dispensing phase such that a precise fluid output is subsequently possible by clocked actuation of the dispensing valve until the target fluid amount has been reached.

Abstract: An agent interfaces with a sending computing device and a receiving computing device to automatically adjust one-way or two-way real-time audio and real-time video transmission parameters responsive to changing network conditions and/or application requirements. The agent incorporates a reinforcement learning model that adjusts transmission parameters to maximize an expected value of a sum of future rewards; the expected value of the sum of future rewards is based on a current state of the sending computing, a current action (e.g. a current set of transmission parameters) at the sending computing device and a reward provided by the receiving computing device. The reward is representative of a user-perceived quality of experience at the receiving computing device.