Patents by Inventor Theodore E. Maione

Theodore E. Maione has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160264625
    Abstract: The subject invention provides advantageous new salts of mu-opiate receptor peptides. These salts have been found to have excellent properties in terms of their activity.
    Type: Application
    Filed: May 30, 2016
    Publication date: September 15, 2016
    Inventor: Theodore E. MAIONE
  • Publication number: 20150152137
    Abstract: The subject invention provides advantageous new salts of mu-opiate receptor peptides. These salts have been found to have excellent properties in terms of their crystal structure, stability, solubility, lack of impurities and/or the ability to be produced, with these advantageous properties, in amounts sufficient for the production of therapeutic compositions.
    Type: Application
    Filed: December 15, 2014
    Publication date: June 4, 2015
    Inventor: Theodore E. MAIONE
  • Publication number: 20150126455
    Abstract: The present invention pertains to novel uses of endomorphine-1 peptide, analogs, and salts thereof for therapy of children, patients currently suffering from drug addiction, patients prone to opioid addiction, and patients with chemo-induced pain.
    Type: Application
    Filed: May 17, 2013
    Publication date: May 7, 2015
    Inventor: Theodore E. Maione
  • Patent number: 8940704
    Abstract: The subject invention provides advantageous new salts of mu-opiate receptor peptides. These salts have been found to have excellent properties in terms of their crystal structure, stability, solubility, lack of impurities and/or the ability to be produced, with these advantageous properties, in amounts sufficient for the production of therapeutic compositions.
    Type: Grant
    Filed: October 17, 2013
    Date of Patent: January 27, 2015
    Assignee: Cytogel Pharma, LLC
    Inventor: Theodore E Maione
  • Publication number: 20140329226
    Abstract: The invention is a method for identifying markers associated with the presence of a predetermined characteristic comprising accumulating spectral data from a sample known to have a predetermined characteristic, identifying a spectral feature which is indicative of the predetermined characteristic, and identifying a marker associated with the spectral feature.
    Type: Application
    Filed: May 8, 2014
    Publication date: November 6, 2014
    Applicant: SEROPTIX, INC.
    Inventor: Theodore E. Maione
  • Publication number: 20140142050
    Abstract: The subject invention provides advantageous new salts of mu-opiate receptor peptides. These salts have been found to have excellent properties in terms of their crystal structure, stability, solubility, lack of impurities and/or the ability to be produced, with these advantageous properties, in amounts sufficient for the production of therapeutic compositions.
    Type: Application
    Filed: October 17, 2013
    Publication date: May 22, 2014
    Applicant: CYTOGEL PHARMA, LLC
    Inventor: THEODORE E MAIONE
  • Publication number: 20110287040
    Abstract: The subject invention pertains to peptides and salts thereof that are useful as anti-inflammatory agents and to compositions containing such peptides and salts as active ingredients. Specifically exemplified herein are endomorphin-1 peptide (EM-1), analogs and salts thereof, and uses for modulation of calcitonin gene-related peptide (CGRP) production and/or substance P (SP) and for treatment of inflammation, particularly neurogenic inflammation.
    Type: Application
    Filed: May 23, 2011
    Publication date: November 24, 2011
    Inventors: Theodore E. Maione, Joseph Carozza, C. Dean Maglaris
  • Publication number: 20110190214
    Abstract: The subject invention provides advantageous new salts of mu-opiate receptor peptides. These salts have been found to have excellent properties in terms of their crystal structure, stability, solubility, lack of impurities and/or the ability to be produced, with these advantageous properties, in amounts sufficient for the production of therapeutic compositions.
    Type: Application
    Filed: December 15, 2008
    Publication date: August 4, 2011
    Inventor: Theodore E. Maione
  • Publication number: 20110065648
    Abstract: The subject invention provides advantageous new salts of mu-opiate receptor peptides. These salts have been found to have excellent properties in terms of their activity.
    Type: Application
    Filed: September 15, 2009
    Publication date: March 17, 2011
    Inventor: Theodore E. Maione
  • Publication number: 20020197600
    Abstract: The present invention relates to a method for determining whether a first biological sample is infected with one of HIV and hepatitis. The first biological sample is obtained from a first mammal. A first and second parameter are compared. A difference between the parameters is indicative of whether the first sample is infected with at least one of HIV and hepatitis. The first parameter is obtained from a fluorescence emission spectrum that results from a first fraction of the first biological sample, the first biological sample having been fractionated into the first fraction and a second fraction. The first fraction includes a greater relative amount of lipoprotein than the second fraction. The second parameter is obtained from a fluorescence emission resulting from a second biological sample obtained from a second, different mammal. The first and second fluorescence emissions are essentially free of fluorescence emission resulting from substances not-native to the first and second mammals, respectively.
    Type: Application
    Filed: May 15, 2002
    Publication date: December 26, 2002
    Inventors: Theodore E. Maione, Yongwu Yang
  • Patent number: 5800820
    Abstract: The subject invention pertains to compositions and methods of treatment of angiogenesis using PF4 and peptide fragments thereof.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: September 1, 1998
    Assignee: Repligen Corporation
    Inventor: Theodore E. Maione
  • Patent number: 5759547
    Abstract: The subject invention pertain to methods of treating Kaposi's Sarcoma and ocular neovascularization using rPF4 and angiogenesis-inhibiting fragments of rPF4.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: June 2, 1998
    Assignee: Repligen Corporation
    Inventor: Theodore E. Maione
  • Patent number: 5616473
    Abstract: The gene encoding the ligninase rLDM.TM. 6 has been cloned and expressed. The ligninases produced via the processes disclosed herein are useful to degrade or modify lignin in pulp operations.
    Type: Grant
    Filed: August 8, 1994
    Date of Patent: April 1, 1997
    Assignee: Clariant Finance (BVI) Limited
    Inventors: Roberta L. Farrell, Paul Gelep, Algis Anilionis, Kashayar Javaherian, Theodore E. Maione, James Rusche, Bruce A. Sadownick, Jennifer A. Jackson
  • Patent number: 5482923
    Abstract: Circulating heparin in a mammal may be neutralized without substantial depletion of platelets or leukocytes by administering to the mammal a heparin neutralizing amount of a purified heparin binding fragment of PF4 or of recombinant PF4.
    Type: Grant
    Filed: April 16, 1993
    Date of Patent: January 9, 1996
    Assignee: Repligen Corporation
    Inventor: Theodore E. Maione
  • Patent number: 5204321
    Abstract: Circulating heparin in a mammal may be neutralized without substantial depletion of platelets or leukocytes by administering to the mammal a heparin neutralizing amount of purified PF4 or rPF4 or a heparin neutralizing fragment thereof.
    Type: Grant
    Filed: June 23, 1992
    Date of Patent: April 20, 1993
    Assignee: Repligen Corporation
    Inventors: Jacquelynn J. Cook, Stefan Niewarowski, Theodore E. Maione
  • Patent number: 5077394
    Abstract: Disclosed are tetraphenyl porphyrins which are beta-substituted by fluoro or chloro and/or bear electronegative substituents on the phenyl including one or two water solubilizing substituents. The new porphorins are particularly suitable as catalysts in a variety of oxidative reactions and methods.
    Type: Grant
    Filed: December 21, 1989
    Date of Patent: December 31, 1991
    Assignee: Sandoz Ltd.
    Inventors: David H. Dolphin, Taku Nakano, Thomas K. Kirk, Tilak P. Wijesekera, Roberta L. Farrell, Theodore E. Maione
  • Patent number: 4892941
    Abstract: Disclosed are tetraphenyl porphyrins which are beta-substituted by fluoro or chloro and/or bear electronegative substituents on the phenyl including one or two water solubilizing substituents. The new porphorins are particularly suitable as catalysts in a variety of oxidative reactions and methods.
    Type: Grant
    Filed: April 15, 1988
    Date of Patent: January 9, 1990
    Inventors: David H. Dolphin, Taku Nakano, Thomas K. Kirk, Tilak P. Wijesekera, Roberta L. Farrell, Theodore E. Maione