Patents by Inventor Theodore L. DeWeese

Theodore L. DeWeese has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Radiation sensitization agents for prostate cancer
    Patent number: 9029340
    Abstract: Compositions and methods are provided for sensitizing neoplastic cells to radiotherapy. The invention provides aptamer-inhibitory nucleic acid chimeras that selectively inliibit the expression of radiosensitizing genes in neoplastic cells expressing a cell surface molecule that binds the aptamer.
    Type: Grant
    Filed: July 22, 2011
    Date of Patent: May 12, 2015
    Assignee: The Johns Hopkins University
    Inventors: Shawn Edward Lupold, Theodore L. DeWeese, Xiaohua Ni, Yonggang Zhang
  • Irreversible inhibitors of DNA polymerase beta
    Patent number: 9029346
    Abstract: Methods and compounds are disclosed for irreversibly inhibiting a DNA repair enzyme that possesses lyase activity.
    Type: Grant
    Filed: December 13, 2013
    Date of Patent: May 12, 2015
    Assignee: The Johns Hopkins University
    Inventors: Marc M. Greenberg, Dumitru Arian, Theodore L. Deweese, Mohammad Hedayati
  • RADIATION SENSITIZATION AGENTS FOR PROSTATE CANCER
    Publication number: 20130123566
    Abstract: Compositions and methods are provided for sensitizing neoplastic cells to radiotherapy. The invention provides aptamer-inhibitory nucleic acid chimeras that selectively inliibit the expression of radiosensitizing genes in neoplastic cells expressing a cell surface molecule that binds the aptamer.
    Type: Application
    Filed: July 22, 2011
    Publication date: May 16, 2013
    Applicant: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Shawn Edward Lupold, Theodore L. DeWeese, Xiaohua Ni, Yonggang Zhang