Patents by Inventor Theodore Whitmore
Theodore Whitmore has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20070298427Abstract: The present invention relates to methods for cost effective, high throughput, multiplexed nucleic acid (gene) expression analysis using photobiotin-labeled anti-sense RNA (aRNA) as hybridization probes in conjunction with a multiplex capable system. The use of the relatively inexpensive photobiotin provides a cost effective alternative to the use of currently available, expensive biotin analogs or other nonradioisotopic labeling methods.Type: ApplicationFiled: June 21, 2007Publication date: December 27, 2007Inventor: Theodore Whitmore
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Publication number: 20070264685Abstract: Novel methods are disclosed for forming a heterodimeric receptor complex with IL-28R and CRF2-4. The methods may be used for detecting and treating viral infections in in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block ligand activity in vitro and in vivo. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.Type: ApplicationFiled: October 9, 2006Publication date: November 15, 2007Inventors: SCOTT PRESNELL, Wenfeng Xu, Julia Novak, Theodore Whitmore, Francis Grant, Wayne Kindsvogel, Kevin Klucher
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Publication number: 20070172889Abstract: The present invention provides novel uses two members of a new family of human proteins, designated as “Zven,” as agents that stimulate gastrointestinal contractility, gastric emptying, intestinal transit, and treating gastroparesis The Zven1 gene, which resides in human chromosome 3p21.1-3p14.3, is expressed in testicular tissue and peripheral blood lymphocytes. The invention also provides methods for using the antibodies to detect the presence of the protein with antibodies and methods for using the polynucleotides to detect the presence of Zven RNA.Type: ApplicationFiled: October 13, 2006Publication date: July 26, 2007Inventors: PAUL SHEPPARD, Paul Bishop, Theodore Whitmore, Penny Thompson
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Publication number: 20070140963Abstract: Novel polypeptide combinations, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17-containing multimeric or heterodimer cytokine receptors that may be used as novel cytokine antagonists, and within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. The present invention also includes methods for producing the multimeric or heterodimeric cytokine receptor, uses therefor and antibodies thereto.Type: ApplicationFiled: October 26, 2006Publication date: June 21, 2007Inventors: Cindy Sprecher, Zeren Gao, Joseph Kuijper, Maria Dasovich, Francis Grant, Scott Presnell, Theodore Whitmore, Angela Hammond, Julia Novak, Jane Gross, Stacey Dillon
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Publication number: 20070140964Abstract: Novel polypeptide combinations, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17-containing multimeric or heterodimer cytokine receptors that may be used as novel cytokine antagonists, and within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. The present invention also includes methods for producing the multimeric or heterodimeric cytokine receptor, uses therefor and antibodies thereto.Type: ApplicationFiled: October 26, 2006Publication date: June 21, 2007Inventors: Cindy Sprecher, Zeren Gao, Joseph Kuijper, Maria Dasovich, Francis Grant, Scott Presnell, Theodore Whitmore, Angela Hammond, Julia Novak, Jane Gross, Stacey Dillon
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Publication number: 20070141051Abstract: Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17, a novel cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block ligand activity in vitro and in vivo. The polynucleotides encoding zcytor17, are located on chromosome 5, and can be used to identify a region of the genome associated with human disease states. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.Type: ApplicationFiled: October 24, 2006Publication date: June 21, 2007Inventors: Cindy Sprecher, Scott Presnell, Zeren Gao, Theodore Whitmore, Joseph Kuijper, Mark Maurer
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Publication number: 20070134727Abstract: Novel methods are disclosed for forming a heterodimeric receptor complex with IL-28R and CRF2-4. The methods may be used for detecting and treating viral infections in in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block ligand activity in vitro and in vivo. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.Type: ApplicationFiled: October 9, 2006Publication date: June 14, 2007Inventors: SCOTT PRESNELL, Wenfeng Xu, Julia Novak, Theodore Whitmore, Francis Grant, Wayne Kindsvogel, Kevin Klucher
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Publication number: 20070122879Abstract: Novel methods are disclosed for forming a heterodimeric receptor complex with IL-28R and CRF2-4. The methods may be used for detecting and treating viral infections in in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block ligand activity in vitro and in vivo. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.Type: ApplicationFiled: October 9, 2006Publication date: May 31, 2007Inventors: Scott Presnell, Wenfeng Xu, Julia Novak, Theodore Whitmore, Francis Grant, Wayne Kindsvogel, Kevin Klucher
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Publication number: 20070117165Abstract: Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor19, a novel class II cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block ligand activity in vitro and in vivo. The polynucleotides encoding zcytor19, are located on chromosome 1p36.11, and can be used to identify a region of the genome associated with human disease states. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.Type: ApplicationFiled: October 6, 2006Publication date: May 24, 2007Inventors: Scott Presnell, Wenfeng Xu, Julia Novak, Theodore Whitmore, Francis Grant
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Publication number: 20070111942Abstract: Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor19, a novel class II cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block ligand activity in vitro and in vivo. The polynucleotides encoding zcytor19, are located on chromosome 1p36.11, and can be used to identify a region of the genome associated with human disease states. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.Type: ApplicationFiled: October 5, 2006Publication date: May 17, 2007Inventors: SCOTT PRESNELL, Wenfeng Xu, Julia Novak, Theodore Whitmore, Francis Grant
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Publication number: 20070105777Abstract: Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17, a novel cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block ligand activity in vitro and in vivo. The polynucleotides encoding zcytorl7, are located on chromosome 5, and can be used to identify a region of the genome associated with human disease states. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.Type: ApplicationFiled: January 8, 2007Publication date: May 10, 2007Inventors: Cindy Sprecher, Scott Presnell, Zeren Gao, Theodore Whitmore, Joseph Kuijper, Mark Maurer
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Publication number: 20070048223Abstract: Novel polypeptide combinations, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17-containing multimeric or heterodimer cytokine receptors that may be used as novel cytokine antagonists, and within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. The present invention also includes methods for producing the multimeric or heterodimeric cytokine receptor, uses therefor and antibodies thereto.Type: ApplicationFiled: October 27, 2006Publication date: March 1, 2007Inventors: Cindy Sprecher, Zeren Gao, Joseph Kuijper, Maria Dasovich, Francis Grant, Scott Presnell, Theodore Whitmore, Angela Hammond, Julia Novak, Jane Gross, Stacey Dillon
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Publication number: 20070048307Abstract: Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zyctor17, a novel cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block ligand activity in vitro and in vivo. The polynucleotides encoding zyctor17, are located on chromosome 5, and can be used to identify a region of the genome associated with human disease states. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.Type: ApplicationFiled: October 20, 2006Publication date: March 1, 2007Inventors: Cindy Sprecher, Scott Presnell, Zeren Gao, Theodore Whitmore, Joseph Kuijper, Mark Maurer
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Publication number: 20070049528Abstract: Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17, a novel cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block ligand activity in vitro and in vivo. The polynucleotides encoding zcytor17, are located on chromosome 5, and can be used to identify a region of the genome associated with human disease states. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.Type: ApplicationFiled: October 20, 2006Publication date: March 1, 2007Inventors: Cindy Sprecher, Scott Presnell, Zeren Gao, Theodore Whitmore, Joseph Kuijper, Mark Maurer
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Publication number: 20070049527Abstract: Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17, a novel cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block ligand activity in vitro and in vivo. The polynucleotides encoding zcytor17, are located on chromosome 5, and can be used to identify a region of the genome associated with human disease states. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.Type: ApplicationFiled: October 20, 2006Publication date: March 1, 2007Inventors: Cindy Sprecher, Scott Presnell, Zeren Gao, Theodore Whitmore, Joseph Kuijper, Mark Maurer
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Publication number: 20070048831Abstract: Novel polypeptide combinations, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17-containing multimeric or heterodimer cytokine receptors that may be used as novel cytokine antagonists, and within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. The present invention also includes methods for producing the multimeric or heterodimeric cytokine receptor, uses therefor and antibodies thereto.Type: ApplicationFiled: October 25, 2006Publication date: March 1, 2007Inventors: Cindy Sprecher, Zeren Gao, Joseph Kuijper, Maria Dasovich, Francis Grant, Scott Presnell, Theodore Whitmore, Angela Hammond, Julia Novak, Jane Gross, Stacey Dillon
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Publication number: 20070048222Abstract: Novel polypeptide combinations, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17-containing multimeric or heterodimer cytokine receptors that may be used as novel cytokine antagonists, and within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. The present invention also includes methods for producing the multimeric or heterodimeric cytokine receptor, uses therefor and antibodies thereto.Type: ApplicationFiled: October 27, 2006Publication date: March 1, 2007Inventors: Cindy Sprecher, Zeren Gao, Joseph Kuijper, Maria Dasovich, Francis Grant, Scott Presnell, Theodore Whitmore, Angela Hammond, Julia Novak, Jane Gross, Stacey Dillon
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Publication number: 20070048309Abstract: Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17, a novel cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block ligand activity in vitro and in vivo. The polynucleotides encoding zcytor17, are located on chromosome 5, and can be used to identify a region of the genome associated with human disease states. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.Type: ApplicationFiled: October 20, 2006Publication date: March 1, 2007Inventors: Cindy Sprecher, Scott Presnell, Zeren Gao, Theodore Whitmore, Joseph Kuijper, Mark Maurer
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Publication number: 20070048835Abstract: Novel polypeptide combinations, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17-containing multimeric or heterodimer cytokine receptors that may be used as novel cytokine antagonists, and within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. The present invention also includes methods for producing the multimeric or heterodimeric cytokine receptor, uses therefor and antibodies thereto.Type: ApplicationFiled: October 25, 2006Publication date: March 1, 2007Inventors: Cindy Sprecher, Zeren Gao, Joseph Kuijper, Maria Dasovich, Francis Grant, Scott Presnell, Theodore Whitmore, Angela Hammond, Julia Novak, Jane Gross, Stacey Dillon
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Publication number: 20070048303Abstract: Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17, a novel cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block ligand activity in vitro and in vivo. The polynucleotides encoding zcytor17, are located on chromosome 5, and can be used to identify a region of the genome associated with human disease states. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.Type: ApplicationFiled: October 24, 2006Publication date: March 1, 2007Inventors: Cindy Sprecher, Scott Presnell, Zeren Gao, Theodore Whitmore, Joseph Kuijper, Mark Maurer