Patents by Inventor Theresa M. McCallum

Theresa M. McCallum has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PCR primers for detection of legionella species and methods for controlling visual intensity in hybridization assays
    Patent number: 5614388
    Abstract: This invention provides for superior nucleic acid primers for amplification of select target regions of the genome of the genus Legionella. The invention facilitates detection of pathogenic and nonpathogenic forms of this genus. The invention further provides for processes for using the primers in template dependent nucleic acid polymerase extension reactions to amplify select target regions. Kits for the use of these primers are also provided.This invention further provides for methods of controlling the intensity of visual signal for detection of duplex formation in nucleic acid hybridization assays under high stringent conditions. This method involves the blending of different capture probes onto a solid support.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: March 25, 1997
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Teresa K.H. Picone, Theresa M. McCallum, Michael A. Zoccoli
  • PCR primers for detection of legionella species and methods for controlling visual intensity in hybridization assays
    Patent number: 5491225
    Abstract: This invention provides for superior nucleic acid primers for amplification of select target regions of the genome of the genus Legionella. The invention facilitates detection of pathogenic and nonpathogenic forms of this genus. The invention further provides for processes for using the primers in template dependent nucleic acid polymerase extension reactions to amplify select target regions. Kits for the use of these primers are also provided. This invention further provides for methods of controlling the intensity of visual signal for detection of duplex formation in nucleic acid hybridization assays under high stringent conditions. This method involves the blending of different capture probes onto a solid support.
    Type: Grant
    Filed: May 27, 1993
    Date of Patent: February 13, 1996
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Teresa K. H. Picone, Theresa M. McCallum, Michael A. Zoccoli