Abstract: The disclosure generally relates to compositions and methods for the production of nucleic acid molecules. In some aspects, the invention allows for the microscale generation of nucleic acid molecules, optionally followed by assembly of these nucleic acid molecules into larger molecules. In some aspects, the invention allows for efficient production of nucleic acid molecules (e.g., large nucleic acid molecules such as genomes).

Abstract: The invention is related to a method and system for calibrating an eye tracking device configured to track a gaze point of a user on a display The method comprises: presenting a video on the display to a user, the video having a start size and a start position; tracking the gaze of the user, using an image sensor of the eye tracking device; and sequentially completing, for at least one calibration position, the steps of: resizing the video to a calibration size, wherein the calibration size is smaller than the start size, and translating the video to a calibration position; recording calibration data, using the eye tracking device, for the user viewing the video in the calibration position; and resizing the video to a second size that is greater than the start size.

Abstract: A catheter system (10) is proposed for preventing biological growth on a catheter (12). The system comprises: a catheter (12) comprising a tube (24) having an inner surface (18), an outer surface (20), and at least a first layer (16) comprising a flexible and electrically conductive first polymer material arranged to conduct an electric current along the tube (24). The system (10) further comprises: an electric power source (14) configured to generate an electric current in the first layer (16).

Abstract: A heat exchanger assembly (10) is proposed comprising: a heat exchanger (12) forming one or more electrically connected partitions (26) separating a first fluid (22) and a second fluid (24). The assembly (10) further comprises: a first electrical connector (14) and a second electrical connector (16) that are operationally connected to the partitions (26) of the heat exchanger (12) and an electrical power source (18) operationally connected to the first electrical connector (14) and the second electrical connector (16). The electrical power source (18) is configured to supply an electric current to the one or more partitions (26) of the heat exchanger (12) via the first electrical connector (14) and the second electrical connector (16).

Abstract: The present invention relates to a method for determining a desired speed of a vehicle (1), preferably an autonomous vehicle. The vehicle comprises a shock absorber arrangement (2), preferably an hydraulic shock absorber arrangement, having an elastic hysteresis. The method comprises—obtaining (501) a reference value indicative of the energy dissipated by the shock absorber arrangement (2) in a reference driving condition of a vehicle and—determining (502) a speed of the vehicle for which the value indicative of the energy dissipated by the shock absorber arrangement (2) in a similar driving condition is expected to fall within a predetermined energy dissipation range, using said reference value.

Abstract: A wheel hub drive system includes a drive motor with a drive shaft, an input planetary gear set (PGS), an output PGS and an intermediate PGS. Each PGS includes a sun gear, a planet carrier and planet gears provided upon the planet carrier. The drive shaft is rotationally fixed with the sun gear of the input PGS. The planet carrier of the input PGS is rotationally fixed with the sun gear of the intermediate PGS, and the planet carrier of the intermediate PGS is rotationally fixed with the sun gear of the output PGS. The planet carrier of the output PGS is adapted to be rotationally fixed with a rim of a wheel. The output PGS is provided axially in-between the input PGS and the intermediate PGS.

Abstract: The proposed technology relates to a system (8) for preventing microbiological growth in a conduit conveying a liquid. The system (8) comprises a multi-layered pipe (10) constituting said conduit and having an inner layer (12) that covers the complete inside (16) of the pipe (10) and is formed of an electrically conductive polymer material. A liquid in the pipe (10) is in direct contact with the inner layer (12). The system further has a first electrical connector (18) and a second electrical connector (19) connecting to the inner layer (12) from outside the pipe (10), wherein the first electric connector (18) and the second electric connector (19) are spaced apart along the pipe (10). The system further has an electric power source (20) operationally connected to the first electrical connector (18) and the second electrical connector (19) and configured for supplying an electric current to the inner layer (12).

Abstract: The present invention relates to a method for determining a functional status of a vehicle shock absorber arrangement (100). The method determines a difference between force values during compression and expansion of the vehicle shock absorber arrangement (100), whereby the shock absorber arrangement (100) can be determined to be degraded if the difference is below a predetermined threshold.

Abstract: A wheel hub arrangement for a driving wheel of a vehicle is provided. The wheel hub arrangement is provided with a planetary gear train including: a centrally arranged sun gear wheel fixed to a drive shaft that extends in an axial direction of the wheel hub arrangement; a set of planet gear wheels distributed circumferentially around and meshing with the sun gear wheel; a ring gear wheel member extending circumferentially around the planet gear wheels and being provided with a ring gear wheel meshing with the planet gear wheels; a stationary planet wheel carrier; an annular rolling-element bearing arranged between the ring gear wheel member and the planet wheel carrier, wherein the ring gear wheel member is configured to be fixed to the driving wheel of the vehicle.

Abstract: A wheel hub drive system includes a drive motor with a drive shaft, an input planetary gear set (PGS), an output PGS and an intermediate PGS. Each PGS includes a sun gear, a planet carrier and planet gears provided upon the planet carrier. The drive shaft is rotationally fixed with the sun gear of the input PGS. The planet carrier of the input PGS is rotationally fixed with the sun gear of the intermediate PGS, and the planet carrier of the intermediate PGS is rotationally fixed with the sun gear of the output PGS. The planet carrier of the output PGS is adapted to be rotationally fixed with a rim of a wheel. The output PGS is provided axially in-between the input PGS and the intermediate PGS.

Abstract: The present disclosure relates to pharmaceutical compositions suitable for oral administration, and more particularly to pharmaceutical compositions, including pharmaceutical tablet compositions, containing (2S)-N-{(1S)-1-cyano-2-[4-(3-methyl-2-oxo-2,3-dihydro-1,3-benzoxazol-5-yl)phenyl]ethyl}-1,4-oxazepane-2-carboxamide (Compound A) or a pharmaceutically acceptable salt thereof.

Abstract: A wheel hub arrangement for a driving wheel of a vehicle is provided. The wheel hub arrangement is provided with a planetary gear train including: a centrally arranged sun gear wheel fixed to a drive shaft that extends in an axial direction of the wheel hub arrangement; a set of planet gear wheels distributed circumferentially around and meshing with the sun gear wheel; a ring gear wheel member extending circumferentially around the planet gear wheels and being provided with a ring gear wheel meshing with the planet gear wheels; a stationary planet wheel carrier; an annular rolling-element bearing arranged between the ring gear wheel member and the planet wheel carrier, wherein the ring gear wheel member is configured to be fixed to the driving wheel of the vehicle.

Abstract: An air suspension arrangement arranged to be connected between a vehicle axle and a vehicle chassis of a vehicle includes a flexible bellows having an upper portion connectable to the vehicle chassis of the vehicle, and a bumper stop, wherein the air suspension arrangement further includes a polymer member arranged between the bumper stop and the flexible bellows for connecting the bumper stop to the flexible bellows. A method for manufacturing the air suspension arrangement and a vehicle including such an air suspension arrangement are also provided.

Abstract: The present invention relates to a method for determining aging of a vehicle suspension arrangement (100) arranged between a frame and a wheel axle of a vehicle, said suspension arrangement (100) comprising a flexible bellows (102) for damping motions from said wheel axle, the method comprising the steps of determining a distance moved by a portion of the flexible bellows (102) when the suspension arrangement is exposed to an external load; determining a gas pressure level within said flexible bellows (102) when the portion of said flexible bellows (102) has moved said distance; determining a relationship between the determined gas pressure level within said flexible bellows and said distance moved by the portion of the flexible bellows; comparing the relationship with a predetermined threshold level; and determining that said flexible bellows is aged if a difference between the relationship and the predetermined threshold level is outside a predetermined threshold range.

Abstract: The present invention relates to a method for determining a desired speed of a vehicle (1), preferably an autonomous vehicle. The vehicle comprises a shock absorber arrangement (2), preferably an hydraulic shock absorber arrangement, having an elastic hysteresis. The method comprises—obtaining (501) a reference value indicative of the energy dissipated by the shock absorber arrangement (2) in a reference driving condition of a vehicle and—determining (502) a speed of the vehicle for which the value indicative of the energy dissipated by the shock absorber arrangement (2) in a similar driving condition is expected to fall within a predetermined energy dissipation range, using said reference value.

Abstract: A planet carrier for a planetary gear transmission for driving a wheel includes a housing for accommodating a sun wheel and planet wheels of a planetary gear transmission. The housing has an inner end and an opposite outer end. The inner end of the housing is provided with an inner end wall having an opening for receiving a drive shaft for driving the sun wheel. The outer end of the housing is provided with an outer end wall having through holes for mounting the planet wheels axially into the housing in the direction from the outer end towards the inner end.

Abstract: The present invention relates to a method for determining a functional status of a vehicle shock absorber arrangement (100). The method determines a difference between force values during compression and expansion of the vehicle shock absorber arrangement (100), whereby the shock absorber arrangement (100) can be determined to be degraded if the difference is below a predetermined threshold.

Abstract: A method, performed by a centrifuge, for treating toughness and hardness of drill bit buttons is provided. The centrifuge comprises a chamber formed by a stationary side wall and a bottom which is rotatable around a rotation axis, the bottom comprising one or more protrusions which at least partly extends between the rotation axis and the side wall, the side wall comprising at least six pushing elements arranged around a periphery of the side wall. The method comprises rotating, by rotation of the bottom with the protrusions, the drill bit buttons around the rotation axis, pushing, by the pushing elements, the drill bit buttons from the side wall during the rotation of the bottom, collectively forming the drill bit buttons into a torus shape at the bottom of the chamber for inducing collisions between the drill bit buttons, thereby treating the toughness and hardness of the drill bit.

Abstract: A wheel hub unit is provided including at least one planetary gear set, including a sun gear, one set of planet gears, a carrier, and a ring gear, wherein each of the planet gears of the set of planet gears is provided with an engagement arrangement adapted for engagement with a corresponding engagement arrangement of the ring gear, wherein the engagement is provided at an engagement area in which the engagement arrangement of the planet gears overlap the engagement arrangement of the ring gear, a bearing, including an inner bearing ring, an outer bearing ring and rolling elements, wherein the inner bearing ring constitutes the ring gear of the planetary gear set, and wherein a center of each of the respective rolling elements is axially displaced in relation to the engagement area. A vehicle including such a wheel hub unit is also provided.

Abstract: A method for controlling gear shifting of a working machine includes determining a representation of a first total tractive force of the working machine for the entire set of drive units; initiating a procedure for redistributing the tractive force while maintaining the first total tractive force, including decreasing, at least partly towards a level suitable for shifting gear, the torque and tractive force of at least the first drive unit down, and increasing, in a compensational manner, the torque and tractive force of at least one of the other drive units not subject to gear shifting; monitoring, during the redistribution procedure, a representation of a second total tractive force of the working machine for the other drive units not subject to gear shifting, and, provided that the second total tractive force exceeds a threshold limit that forms a function of the first total tractive force: decreasing the torque and tractive force of at least the first drive unit down to the level suitable for shifting gea