Abstract: The present application relates to a diagnostic composition comprising: a. a compound of Formula I, b. ethanol, c. water, and d. a hydroxycarboxylic acid, a salt of a hydroxycarboxylic acid or a mixture thereof. The diagnostic composition can be used in the selective detection of disorders and abnormalities associated with Tau aggregates such as Alzheimer's disease (AD) and other tauopathies, for example, using Positron Emission Tomography (PET). The present invention also relates to a method of preparing the claimed diagnostic composition.

Abstract: The present invention is directed towards new 18F-folate/antifolate analog radiopharmaceuticals, wherein the phenyl group within folate structures has been replaced by an 18F-heterocycle, their precursors, a method of their preparation, as well as their use in diagnosis of a cell or population of cells expressing a folate-receptor and monitoring of cancer and inflammatory and autoimmune diseases and therapy thereof.

Abstract: The present invention is directed towards new 18F-folate/antifolate analogue radiopharmaceuticals, wherein the phenyl group within folate structures has been replaced by an 18F-heterocycle, their precursors, a method of their preparation, as well as their use in diagnosis of a cell or population of cells expressing a folate-receptor and monitoring of cancer and inflammatory and autoimmune diseases and therapy thereof.

Abstract: The gas distributor apparatus has a common gas-supply line for supplying gas to a plurality of devices, e.g., arranged in series, the gas-supply line representing a substructure with an inner supply orifice and connecting pieces, which conform in number to the devices for injecting a fuel-gas mixture, and which extend in a normal direction starting from the gas-supply line and contain branched-off ports that communicate directly with the supply orifice. A permanent connection is established between the gas distributor apparatus and the devices in that gas-intake ducts are configured on the gas-containing bodies at least partially surrounding the devices, the gas-intake ducts having functional elements and projecting with these elements into the connecting pieces of the gas distributor apparatus. The gas is made available simultaneously for all devices in the supply orifice and then flows in each case via one connecting piece to a device.

Abstract: A housing body of a fuel injector has a multi-part design; it includes a base member and at least one calibrating sleeve. Air is supplied and metered in through the calibrating sleeve, while the base member is used for sealing and attachment purposes. A dimensionally accurate machining of calibrating sleeves can be carried out simply and cost-effectively. The structural design easily yields many different variants. The fuel injector is especially suited for fuel-injection systems of mixture-compressing internal combustion engines having externally supplied ignition.

Abstract: A fuel delivery system for an internal combustion engine having an intake air metering device, leading to individual combustion chambers several fuel injection valves, each of which is assigned to one combustion chamber, and a central fuel vaporizer to which fuel can be supplied by a fuel metering device. To reduce pollutant emissions during the warm-up phase of the internal combustion engine after start-up, fuel vapor generated in the fuel vaporizer can be added to the intake air for the combustion chambers downstream from the intake air metering device.