Patents by Inventor Thomas Bodmer

Thomas Bodmer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Rapid detection of antibiotic resistance in mycobacterium tuberculosis
    Patent number: 6124098
    Abstract: A nucleotide sequence encoding a katG/lacZ fusion protein is useful for assaying the enzymatic activity of the katG gene product. A process of selecting a compound that is toxic against an isoniazid-resistant mycobaterial strain comprises incubating a catalase peroxidase enzyme with an isoniazid to produce a compound that restores isoniazid susceptability to the isoniazid-resistant mycobaterial strain.
    Type: Grant
    Filed: May 20, 1998
    Date of Patent: September 26, 2000
    Assignees: Institut Pasteur, Medical Research Council, Assistance Publique, Universite Pierre et Marie Curie (Paris VI), Universite de Berne
    Inventors: Beate Heym, Stewart Cole, Douglas Young, Ying Zhang, Nadine Honore, Amalio Telenti, Thomas Bodmer
  • Rapid detection of antibiotic resistance in mycobacterium tuberculosis
    Patent number: 5851763
    Abstract: A process for the detection of resistance to an antibiotic in a mycobacterium comprises detecting a mutation in a gene selected from the group consisting of the katG gene or fragment thereof, the rpoB gene or fragment thereof, and the rpsI gene or fragment thereof. The process is useful for detecting in vitro the presence of nucleic acids of a Mycobacterium tuberculosis resistant to isoniazid.
    Type: Grant
    Filed: October 12, 1994
    Date of Patent: December 22, 1998
    Assignee: Institut Pasteur
    Inventors: Beate Heym, Stewart Cole, Douglas Young, Ying Zhang, Nadine Honore, Amalio Telenti, Thomas Bodmer