Patents by Inventor Thomas Buch-Rasmussen
Thomas Buch-Rasmussen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 8518430Abstract: Solid pharmaceutical compositions for parenteral injection comprising a binder and at least one therapeutic agent. The pharmaceutical composition has the strength to be injected directly with the need of using cannulas or the like.Type: GrantFiled: October 31, 2011Date of Patent: August 27, 2013Assignee: Novo Nordisk A/SInventors: Thomas Buch-Rasmussen, James M. Flink, Jens Ulrich Poulsen, Søren Aasmul, Philip Hansen, Claus Juul Mortensen
-
Patent number: 8454997Abstract: A solid pharmaceutical composition for parenteral administration having an inner matrix containing at least one therapeutic agent, and a biodegradable, and water-impermeable coating covering part of the surface of said composition. The inner matrix disintegrates upon contact with animal tissue or tissue fluids. By providing a disintegratable and/or soluble inner matrix comprising the drug with a water-impermeable coating covering part of the surface of said composition, the rate of release of the drug can be controlled. The specific rate of release can be controlled by carefully designing the part of the surface which is not covered.Type: GrantFiled: December 18, 2002Date of Patent: June 4, 2013Assignee: Novo Nordisk A/SInventors: Henrik Egesborg Hansen, Thomas Buch-Rasmussen, Mads Christian Sabra
-
Publication number: 20120082724Abstract: Solid pharmaceutical compositions for parenteral injection comprising a binder and at least one therapeutic agent. The pharmaceutical composition has the strength to be injected directly with the need of using cannulas or the like.Type: ApplicationFiled: October 31, 2011Publication date: April 5, 2012Applicant: Novo Nordisk A/SInventors: THOMAS BUCH-RASMUSSEN, Søren Aasmul, James M. Flink, Philip Hansen, Jens Ulrik Poulsen, Claus Juul-Mortensen
-
Patent number: 8084053Abstract: Solid pharmaceutical compositions and methods of making and administering for parenteral injection comprising a binder and at least one therapeutic agent. The pharmaceutical composition has the strength to be injected directly with the need of using cannulas or the like.Type: GrantFiled: August 7, 2009Date of Patent: December 27, 2011Assignee: Novo Nordisk A/SInventors: Thomas Buch-Rasmussen, James M. Flink, Jens Ulrich Poulsen, Søren Aasmul, Philip Hansen, Claus Juul Mortensen
-
Publication number: 20100196477Abstract: Solid pharmaceutical compositions and methods of making and administering for parenteral injection comprising a binder and at least one therapeutic agent. The pharmaceutical composition has the strength to be injected directly with the need of using cannulas or the like.Type: ApplicationFiled: August 7, 2009Publication date: August 5, 2010Applicant: Novo Nordisk A/SInventors: Thomas Buch-Rasmussen, Søren Aasmul, James M. Flink, Phillip Hansen, Claus Juul, Jens Ulrich Poulsen
-
Patent number: 7666844Abstract: Solid pharmaceutical compositions for parenteral injection comprising a binder and at least one therapeutic agent. The pharmaceutical composition has the strength to be injected directly with the need of using cannulas or the like.Type: GrantFiled: February 7, 2005Date of Patent: February 23, 2010Assignee: Novo Nordisk A/SInventors: Thomas Buch-Rasmussen, James M. Flink, Jens Ulrich Poulsen, Søren Aasmul, Philip Hansen, Claus Juul Mortensen
-
Publication number: 20080255440Abstract: A sensor package is provided comprising an implantable sensor having an electrode area and an electric contact area, the package comprising a shielding packaging enclosing at least the electrode area of the sensor while exposing the electric contact area. The sensor package fascilitates handling of the implantable sensor and provides for the possibility of sterilising the electric contact area leaving the electrode area protected.Type: ApplicationFiled: July 13, 2005Publication date: October 16, 2008Applicant: Novo Nordisk A/SInventors: Michael Eilersen, Thomas Buch-Rasmussen, Kristian Glejbol
-
Patent number: 7344766Abstract: The present invention relates to the field of pharmaceutical packaging. More specifically the present invention relates to a stopper made from a thermoplastic elastomer for the use in medical containers.Type: GrantFiled: May 22, 2000Date of Patent: March 18, 2008Assignee: Novo Nordisk A/SInventors: Anne Sørensen, Thomas Buch-Rasmussen, Ulrik Nøsted
-
Publication number: 20050202072Abstract: Solid pharmaceutical compositions for parenteral injection comprising a binder and at least one therapeutic agent. The pharmaceutical composition has the strength to be injected directly with the need of using cannulas or the like.Type: ApplicationFiled: February 7, 2005Publication date: September 15, 2005Applicant: Novo Nordisk A/SInventors: Thomas Buch-Rasmussen, Soren Aasmul, James Flink, Philip Hansen, Jens Poulsen, Claus Juul-Mortensen
-
Patent number: 6755810Abstract: The present invention relates to a transfer device for transferring medicament from a medicament container to a syringe with a needle. The transfer device is arranged for transferring accurate dosages of insulin, growth hormone or other medicaments. The accuracy is ensured by the device comprising means for mounting a syringe to the device, the needle piercing a sealing of the device. Opposite the sealing a piston is arranged, said piston being non-releasable engaged with the piston driver during transfer of the medicament. Thereby the piston is not erroneously drawn from the piston driver, which would otherwise lead to incorrect dosing. Furthermore, the device comprises dosing means including the piston driver.Type: GrantFiled: September 20, 2001Date of Patent: June 29, 2004Assignee: Novo Nordisk A/SInventors: Thomas Buch-Rasmussen, Jens-Ulrik Poulsen, Henrik Ljunggreen
-
Patent number: 6680091Abstract: A medicament container for storing a liquid medicament, such as insulin, comprises a wall with at least two opposite portions made of a polymer material having a light transmission at 400 nm of at least 25%, a glass transition temperature above 50° C., and a density of 0.95 g/cm3 or more. The polymer material comprises at least 70% by weight of a copolymer material composed of aliphatic cyclic or bicyclic hydrocarbons with 5 to 7 membered ring or rings and ethylene or propylene. The container is substantially inert to the medicament and, because it is either transparent or at least includes at least two opposed transparent portions, it is possible visually to inspect the contents of the container to make sure that the medicament has not crystalized or polymerized. The walls of the container provide a good barrier against m-cresol/phenol/benzyl alcohol preservatives and water.Type: GrantFiled: December 16, 1997Date of Patent: January 20, 2004Assignee: Novo Nordisk A/SInventors: Thomas Buch-Rasmussen, Patric Jannasch, Erling Bonne Jørgensen
-
Publication number: 20030234466Abstract: The present invention relates to a method of producing a pharmaceutical composition directly in a packaging material, a moulded packaging material comprising the pharmaceutical composition, a cassette comprising the packaging material, as well as a method of administering a dosage of the pharmaceutical composition for example directly from the packaging material.Type: ApplicationFiled: January 13, 2003Publication date: December 25, 2003Inventors: Thomas Buch Rasmussen, Aasmul Soren, Jens Ulrik Poulsen, James M. Flink, Philip Hansen, Juul Mortensen Claus
-
Patent number: 6660197Abstract: The present invention relates to a method and a system for producing an elongated drug formulation being suitable for being injected through the skin of a patient with-out the use of a needle or a cannula. The drug formulation is produced by compressing a drug granulate in cavity of a system comprising a roller and a surface, wherein the roller roles over the surface thereby comprising the granulate to the formulation.Type: GrantFiled: October 12, 2000Date of Patent: December 9, 2003Assignee: Novo Nordisk A/SInventors: Thomas Buch-Rasmussen, Søren Aasmul, James M. Flink, Philip Hansen, Claus Juul-Mortensen, Jens-Ulrik Poulsen
-
Publication number: 20030187422Abstract: In a medical injection device an ampoule containing a fluid to be injected has a resilient piston closing on one end of the ampoule, which resilient piston is moved forward by a plunger. A membrane closes the other end of the ampoule. An injection needle projecting through the membrane of the ampoule and into the ampoule is mounted prior to use. To protect the pointed end of the needle projecting into the ampoule from being damaged by the resilient piston when the ampoule is about to be empty and the piston is moved close to the membrane, the resilient piston has a central part of the front wall lowered relative to the rest of the front wall to provide a central well in the front wall.Type: ApplicationFiled: April 22, 2003Publication date: October 2, 2003Inventors: Thomas Buch-Rasmussen, Jens Ulrik Poulsen, Henrik Ljunggreen
-
Publication number: 20030170410Abstract: A medicament container for storing a liquid medicament, such as insulin, comprises a wall with at least two opposite portions made of a polymer material having a light transmission at 400 nm of at least 25%, a glass transition temperature above 50° C., and a density of 0.95 g/cm3 or more. The polymer material comprises at least 70% by weight of a copolymer material composed of aliphatic cyclic or bicyclic hydrocarbons with 5 to 7 membered ring or rings and ethylene or propylene. The container is substantially inert to the medicament and, because it is either transparent or at least includes at least two opposed transparent portions, it is possible visually to inspect the contents of the container to make sure that the medicament has not crystalized or polymerized. The walls of the container provide a good barrier against m-cresol/phenol/benzyl alcohol preservatives and water.Type: ApplicationFiled: December 16, 1997Publication date: September 11, 2003Inventors: THOMAS BUCH-RASMUSSEN, PATRIC JANNASCH, ERLING BONNE JORGENSEN
-
Publication number: 20030161881Abstract: A solid pharmaceutical composition for parenteral administration having an inner matrix containing at least one therapeutic agent, and a biodegradable, and water-impermeable coating covering part of the surface of said composition. The inner matrix disintegrates upon contact with animal tissue or tissue fluids. By providing a disintegratable and/or soluble inner matrix comprising the drug with a water-impermeable coating covering part of the surface of said composition, the rate of release of the drug can be controlled. The specific rate of release can be controlled by carefully designing the part of the surface which is not covered.Type: ApplicationFiled: December 18, 2002Publication date: August 28, 2003Inventors: Henrik Egesborg Hansen, Thomas Buch-Rasmussen, Mads Christian Sabra
-
Patent number: 6582408Abstract: The present invention relates to a medication delivery device comprising a cartridge assembly, a dosing assembly and optionally a needle assembly. The cartridge assembly comprises a cartridge having a stopper adapted to receive a plunger. Furthermore, the cartridge assembly has one end sealed with a pierce able sealing, said end comprising coupling device for engaging a needle assembly, and another end comprising coupling device for engaging the dosing assembly. The dosing assembly comprises a plunger and has coupling device for engaging the cartridge assembly. The cartridge assembly and the dosing assembly are coupled together for delivering selected doses of medication. The device further comprises mechanism for securing that the plunger abuts on the stopper during use of the device, in particular when the dosing assembly is releasable coupled to the cartridge assembly.Type: GrantFiled: July 8, 1999Date of Patent: June 24, 2003Inventors: Thomas Buch-Rasmussen, Benny Munk, Jens Ulrik Poulsen, Henrik Ljungreen, Peter Møller Jensen, Jens Møller Jensen
-
Patent number: 6562011Abstract: The present invention relates to a medication delivery device comprising a cartridge assembly, a dosing assembly and optionally a needle assembly. The cartridge assembly comprises a cartridge having a stopper adapted to receive a plunger means. Furthermore, the cartridge assembly has one end sealed with a pierceable sealing, said end comprising coupling means for engaging a needle assembly, and another end comprising coupling means for engaging the dosing assembly. At least one of the coupling means of the cartridge assembly is unitarily moulded with the cartridge. The dosing assembly comprises a plunger means and has coupling means for engaging the cartridge assembly. The cartridge assembly and the dosing assembly are coupled together for delivering selected doses of medication. The cartridge is preferably moulded from a plastic material, such as a transparent material, and may be housed in a cartridge housing for protection of the cartridge.Type: GrantFiled: July 7, 1999Date of Patent: May 13, 2003Assignee: Novo Nordisk A/SInventors: Thomas Buch-Rasmussen, Benny Munk, Jens Ulrik Poulsen, Henrik Ljungreen, Peter Møller Jensen, Jens Møller Jensen
-
Patent number: 6485453Abstract: A cassette for storing and insertion of a solid medicine peg appears as a unit having a first bore (2) which accommodates the medicine peg (3) and has a diameter corresponding to the diameter of this peg (3), a second bore (4) in coaxial extension of the first bore (2) and having a diameter larger than the diameter of the first bore (2), an inserter having a shaft (5) fitting into the first bore (2) and a guiding head (6) in coaxial extension of the shaft (5) fitting into the second bore. The inserter shaft (5) has one end adjacent to the peg (3) and the other connected to the guiding head (6) which projects from the cassette. The head (6) fits into the second bore with a fitting providing a diffusion tight sealing and the distal end of the unit is closed by a membrane diffusion tightly sealing this distal end.Type: GrantFiled: April 13, 2000Date of Patent: November 26, 2002Assignee: Novo Nordisk A/SInventors: Thomas Buch-Rasmussen, Søren Aasmul, James M. Flink, Philip Hansen, Claus Juul-Mortensen, Jens Ulrik Poulsen
-
Patent number: 6482509Abstract: The present invention relates to a coating system, in particular to a coating system for articles where plastic materials slide against flexible rubber materials. The coating system is a silicone oil based coating having a viscosity of at least 200,000 centistokes, i.e. a high viscosity coating. The coating comprises in a preferred embodiment a silicone oil based block or graft copolymer, or segmented copolymer. Further the invention relates to a process of producing a component of an article coated as described above, comprising adding the coating material to the component material prior to molding and subsequently molding the component from the mixture, or molding the component from the component material and subsequently applying the coating material to the at least one surface of the component, as well as an article coated with a silicone oil based coating as defined above. Such an article is preferably a medical article, such as a container or an injection cylinder and a stopper.Type: GrantFiled: March 2, 1999Date of Patent: November 19, 2002Assignee: Novo Nordisk A/SInventors: Thomas Buch-Rasmussen, Patric Jannasch, Erling Bonne Jørgensen, Ib Johannesen, Sokol Ndoni, Nils Berg Madsen