Abstract: A fastener cartridge can include, one, a cartridge body comprising a deck and a plurality of fastener cavities and, two, a plurality of fasteners positioned in the fastener cavities. The cartridge body can further comprise extensions extending from the deck having different sizes and/or configurations. The extensions can control the flow of tissue relative to the deck and/or support the fasteners as they are ejected from the fastener cavities.

Abstract: Described herein are photonic communication platforms that can overcome the memory bottleneck problem, thereby enabling scaling of memory capacity and bandwidth well beyond what is possible with conventional computing systems. Some embodiments provide photonic communication platforms that involve use of photonic modules. Each photonic module includes programmable photonic circuits for placing the module in optical communication with other modules based on the needs of a particular application. The architecture developed by the inventors relies on the use of common photomask sets (or at least one common photomask) to fabricate multiple photonic modules in a single wafer. Photonic modules in multiple wafers can be linked together into a communication platform using optical or electronic means.

Abstract: Described herein are photonic communication platforms that can overcome the memory bottleneck problem, thereby enabling scaling of memory capacity and bandwidth well beyond what is possible with conventional computing systems. Some embodiments provide photonic communication platforms that involve use of photonic modules. Each photonic module includes programmable photonic circuits for placing the module in optical communication with other modules based on the needs of a particular application. The architecture developed by the inventors relies on the use of common photomask sets (or at least one common photomask) to fabricate multiple photonic modules in a single wafer. Photonic modules in multiple wafers can be linked together into a communication platform using optical or electronic means.

Abstract: A fastener cartridge can include, one, a cartridge body comprising a deck and a plurality of fastener cavities and, two, a plurality of fasteners positioned in the fastener cavities. The cartridge body can further comprise extensions extending from the deck having different sizes and/or configurations. The extensions can control the flow of tissue relative to the deck and/or support the fasteners as they are ejected from the fastener cavities.

Abstract: A linkage extends between an actuator and a valve in a turbocharger. The linkage comprises two spaced member bodies having central portions with opposing curved shapes that extend between ends translatable along and rotatable about spaced pivots. Translation of one member toward the other member compresses the central portions, increasing overall stiffness of the linkage, and translation of one member away from the other member creates a gap between the central portions, allowing independent translation of the ends along the spaced pivots to compensate for misalignment between the actuator and the valve caused by heat and vibration. Another linkage extending between an actuator and a valve in a turbocharger includes two planar spaced member bodies extending between ends translatable along and rotatable about spaced pivots. The two member bodies have different thicknesses.

Abstract: A linkage extends between an actuator and a valve in a turbocharger. The linkage comprises two spaced member bodies having central portions with opposing curved shapes that extend between ends translatable along and rotatable about spaced pivots. Translation of one member toward the other member compresses the central portions, increasing overall stiffness of the linkage, and translation of one member away from the other member creates a gap between the central portions, allowing independent translation of the ends along the spaced pivots to compensate for misalignment between the actuator and the valve caused by heat and vibration. Another linkage extending between an actuator and a valve in a turbocharger includes two planar spaced member bodies extending between ends translatable along and rotatable about spaced pivots. The two member bodies have different thicknesses.

Abstract: The invention provides methods, uses and compositions for the treatment of hidradenitis suppurativa. The invention describes methods and uses for treating hidradenitis suppurativa, wherein a TNF? inhibitor, such as a human TNF? antibody, or antigen-binding portion thereof, is used to treat hidradenitis suppurativa in a subject. Also described are methods for determining the efficacy of a TNF? inhibitor for treating hidradenitis suppurativa in a subject.

Abstract: The invention provides methods, uses and compositions for the treatment of hidradenitis suppurativa. The invention describes methods and uses for treating hidradenitis suppurativa, wherein a TNF? inhibitor, such as a human TNF? antibody, or antigen-binding portion thereof, is used to treat hidradenitis suppurativa in a subject. Also described are methods for determining the efficacy of a TNF? inhibitor for treating hidradenitis suppurativa in a subject.

Abstract: The invention provides methods, uses and compositions for the treatment of hidradenitis suppurativa. The invention describes methods and uses for treating hidradenitis suppurativa, wherein a TNF? inhibitor, such as a human TNF? antibody, or antigen-binding portion thereof, is used to treat hidradenitis suppurativa in a subject. Also described are methods for determining the efficacy of a TNF? inhibitor for treating hidradenitis suppurativa in a subject.

Abstract: The invention provides methods, uses and compositions for the treatment of hidradenitis suppurativa. The invention describes methods and uses for treating hidradenitis suppurativa, wherein a TNF? inhibitor, such as a human TNF? antibody, or antigen-binding portion thereof, is used to treat hidradenitis suppurativa in a subject. Also described are methods for determining the efficacy of a TNF? inhibitor for treating hidradenitis suppurativa in a subject.

Abstract: The invention provides methods of treating psoriasis in a subject by administering to a subject an antibody capable of binding to the p40 subunit of IL-12 and/or IL-23.

Abstract: The invention provides methods, uses and compositions for the treatment of psoriasis or Crohn's disease. The invention describes methods and uses for treating psoriasis or Crohn's disease, wherein a TNF? inhibitor, such as a human TNF? antibody, or antigen-binding portion thereof, is used to treat psoriasis in a subject. The invention includes methods of improving patient reported outcomes using a human human TNF? antibody, or antigen-binding portion thereof, for the treatment of Crohn's or psoriasis. The invention also provides methods of improving fatigue or depression in patients having Crohns'.

Abstract: The invention provides methods, uses and compositions for the treatment of hidradenitis suppurativa. The invention describes methods and uses for treating hidradenitis suppurativa, wherein a TNF? inhibitor, such as a human TNF? antibody, or antigen-binding portion thereof, is used to treat hidradenitis suppurativa in a subject. Also described are methods for determining the efficacy of a TNF? inhibitor for treating hidradenitis suppurativa in a subject.

Abstract: The invention provides methods, uses and compositions for the treatment of psoriasis or Crohn's disease. The invention describes methods and uses for treating psoriasis or Crohn's disease, wherein a TNF? inhibitor, such as a human TNF? antibody, or antigen-binding portion thereof, is used to treat psoriasis in a subject. The invention includes methods of improving patient reported outcomes using a human TNF? antibody, or antigen-binding portion thereof, for the treatment of Crohn's or psoriasis. The invention also provides methods of improving fatigue or depression in patients having Crohns'.

Abstract: A data processing system for testing a rulebase implemented in a rule evaluation process utilized for transforming fuzzy inputs to fuzzy outputs in a fuzzy logic operation, the rule evaluation process including a plurality of rules, wherein a path in the fuzzy logic operation includes one of the fuzzy inputs specified by the path, one of the plurality of rules specified by the path, and one of the fuzzy outputs specified by the path, wherein the rule evaluation process implements a MIN/MAX method of rule evaluation. The system determines which paths in the fuzzy logic operation can be tested simultaneously, and assigns values to test vectors in order to test the paths in a manner consistent with the determination of which paths in the fuzzy logic operation can be tested simultaneously, wherein paths that can be tested simultaneously can be tested by a same test vector.

Abstract: A cosmetic facial powder composition including filler, mendicant and fragrance ingredients possesses a high degree of transparency and oil absorbency provided by a large amount of the filler content being walnut shell flour having a particle size of not more than about 40 microns. The composition may be in loose or compact powder form.

Abstract: An improved weighing hopper for use with a transition chute in a weighing scale of a packaging machine system is disclosed which provides for better control of the flowable materials in the weighing hopper and the transition chute and comprises forming the bottom surface of at least one weigh hopper and the transition chute into which the weigh hopper dumps its material with a slope that is equal to or greater than an angle of repose of the materials being handled in the weighing hopper. The use of the angle of repose or greater in combination with a controlled opening of the weigh hopper doors aids in controlling the flow of material and minimizes dust generation.

Abstract: An improved transition section for a bag filling device is disclosed for use with a bag filling machine. The device comprises a new and novel transition structure that may be utilized to effectively absorb the energy of the material passing through the filling machine and to effectively control the flow of the material in the transition section so that at least two flow paths are formed within the transition chute throat section with one flow path being utilized for downwardly flow of the material being filled in the bag filling machine and the other flow path being utilized for upwardly flow of dust and air resulting from the filling process. The dual flow paths are formed by a rigid divider member fixedly attached to the control device suspended in the transition chute with the divider member moving in a generally horizontal direction in an arcuate path.