Abstract: Tube and float systems for separation and axial expansion of the buffy coat are provided. Generally, the systems include a flexible sample tube and a rigid separator float having a specific gravity intermediate that of red blood cells and plasma. The sample tube has an elongated sidewall having a first cross-sectional inner diameter. The float has a main body portion and one or more support members protruding from the main body portion to engage and support the sidewall of the sample tube. During centrifugation, the centrifugal force enlarges the diameter of the tube to permit density-based axial movement of the float in the tube. After centrifugation is ended, the tube sidewall returns to its first diameter, thereby capturing the float and trapping the buffy coat constituents in an annular volume. Several different systems for capturing and retrieving the buffy coat constituents are described.

Abstract: Tube and float systems for separation and axial expansion of the buffy coat are provided. Generally, the systems include a flexible sample tube and a rigid separator float having a specific gravity intermediate that of red blood cells and plasma. The sample tube has an elongated sidewall having a first cross-sectional inner diameter. The float has a main body portion and one or more support members protruding from the main body portion to engage and support the sidewall of the sample tube. During centrifugation, the centrifugal force enlarges the diameter of the tube to permit density-based axial movement of the float in the tube. After centrifugation is ended, the tube sidewall returns to its first diameter, thereby capturing the float and trapping the buffy coat constituents in an annular volume. Several different systems for capturing and retrieving the buffy coat constituents are described.

Abstract: There is provided a device that retains a collected sample for on-demand testing of a small portion of the collected sample while the rest of the sample remains for optional additional analysis. The on-demand test provides relatively immediate information about aspects of the sample, e.g. presence of microbes, chemistry, nutritional condition, presence of contaminants.

Abstract: A system for separating and axially expanding the buffy coat is provided that includes a flexible sample tube and a rigid separator float. The sample tube has a sidewall with a first cross-sectional inner diameter. The float includes a main body portion and one or more support members protruding from the main body portion. The float has a cross-sectional diameter less than that of the first cross-sectional inner diameter when the sample tube is expanded. The main body portion of the float and the sidewall define an annular volume therebetween. The support members traverse said annular volume to produce one or more analysis areas. During centrifugation, centrifugal force enlarges the diameter of the tube to permit density-based axial movement of the float. The centrifugal force is reduced to return the tube to its first diameter, thereby capturing the float and trapping the buffy coat constituents in the analysis area.

Abstract: The present invention relates to a one-step fastening device, a process for creating a fastener utilizing such a device, and the end fastener produced thereby. In this regard, the invention uses an outer, hollow fastener material that can be partially compressed under tension at designated areas (i.e., a compression member) and an inner activation or tensioning member. The compression of the outer fastener material occurs at one or more flexible areas or compression features specifically located on the longitudinal axis of the material. As a result, the outer compression member is capable of being distorted or bent under tension to produce a predetermined configuration. The device described herein has the ability to form specific and controllable fasteners of designated shapes and configurations. Methods for fastening, snaring, gripping, cutting, and manipulating material using the device in a confined space are also provided.

Abstract: A cartridge for use by print-disabled users to play digital audio content and a player having a receptacle for receiving the cartridge are provided. The cartridge includes a random-access digital storage device storing the digital audio content and having a connector providing access to the digital audio content; and a casing permanently housing the digital storage device and allowing access to the connector of the digital storage device. The casing has a form facilitating handling of the cartridge by the print-disabled users which includes bevelled edges, and has dimensions comparable to dimensions of a standard compact audio cassette. Preferably, the cartridge has a hole extending through the casing at its back end and a sloped surface on the bottom side of the casing at the back end. The receptacle has a form and shape facilitating insertion of the cartridge therein. It has a lower surface defining an elevated ramp along which the cartridge slides as it is inserted into the player.

Abstract: The present invention relates to the analysis of specimens. Specifically, the invention relates to methods and apparatus for reviewing specimen slides, including apparatus for holding the slides. The invention also relates to an automatic focusing method for an imaging system and methods for accommodating vibration in the imaging system. In particular, the methods and apparatus may be applied to the automated analysis of cytological specimen slides.

Abstract: A test tube (72, 72?) defines a test tube axis (75) and contains or supports an associated sample in an annular sampling region (12). At least two alignment bearings (80, 81, 81?, 82, 83, 110, 140, 142, 181, 182, 183, 184, 211, 212) engage the test tube at opposite sides of the annular sampling region along the test tube axis. At least one bias bearing (86, 86?, 87, 140, 142, 204) is radially spaced apart from the at least two alignment bearings and presses the test tube against the at least two alignment bearings to align a portion of the annular sampling region respective to the at least two alignment bearings. A motor (112) engages the test tube to selectively rotate the test tube.

Abstract: A cartridge for use by print-disabled users to play digital audio content and a player having a receptacle for receiving the cartridge are provided. The cartridge includes a random-access digital storage device storing the digital audio content and having a connector providing access to the digital audio content; and a casing permanently housing the digital storage device and allowing access to the connector of the digital storage device. The casing has a form facilitating handling of the cartridge by the print-disabled users which includes bevelled edges, and has dimensions comparable to dimensions of a standard compact audio cassette. Preferably, the cartridge has a hole extending through the casing at its back end and a sloped surface on the bottom side of the casing at the back end. The receptacle has a form and shape facilitating insertion of the cartridge therein. It has a lower surface defining an elevated ramp along which the cartridge slides as it is inserted into the player.

Abstract: The present invention relates to a one-step fastening device, a process for creating a fastener utilizing such a device, and the end fastener produced thereby. In this regard, the invention uses an outer, hollow fastener material that can be partially compressed under tension at designated areas (i.e., a compression member) and an inner activation or tensioning member. The compression of the outer fastener material occurs at one or more flexible areas or compression features specifically located on the longitudinal axis of the material. As a result, the outer compression member is capable of being distorted or bent under tension to produce a predetermined configuration. The device described herein has the ability to form specific and controllable fasteners of designated shapes and configurations. Methods for fastening, snaring, gripping, cutting, and manipulating material using the device in a confined space are also provided.

Abstract: A tube and float system for use in separation and axial expansion of the buffy coat is provided. The system includes a transparent, or semi-transparent, flexible sample tube and a rigid separator float having a specific gravity intermediate that of red blood cells and plasma. The sample tube has an elongated sidewall having a first cross-sectional inner diameter. The float consists of a main body portion and one or more support members protruding from the main body portion to engage and support the sidewall of the sample tube. The main body portion and the support members of the float have a cross-sectional diameter less than that of the first cross-sectional inner diameter of the tube when the sample tube is expanded, such as by centrifugation. The main body portion of the float together with an axially aligned portion of the sidewall define an annular volume therebetween.

Abstract: The invention includes linkage assemblies comprising coupled links with metallic contact surfaces with improved stiffness. The inventors found significant mechanical problems with all previous descriptions of metallic contact links sufficient to preclude their commercial use. These metallic contact links are a significant improvement over existing plastic ball and metal joint, or all plastic beads as found in the prior art. The invention includes methods providing these links and high friction couplings between them, as well as the linkage assemblies and flexible arms resulting from these processes.

Abstract: A thermal treatment system for supplying thermally conditioned or purified water for human or animal consumption, industrial processes, environmental containment, or removal of foreign species. The water purifier includes a heat exchanger for exchanging heat between outgoing thermally conditioned or purified water and incoming makeup water; a water heater is connected to the heat exchanger so as to receive pre-heated incoming makeup water, where the water heater subsequently heats the incoming preheated makeup water to a set-point temperature in the case of thermally conditioned water and for purified water also holds the water for a period of time sufficient to inactivate selected organisms to a predetermined level. The heat exchanger has one or more treated water outlets for supplying thermally conditioned or purified water at selected temperatures.

Abstract: Machinery for automated manufacture of formed wire structures such as innerspring assemblies for mattresses and seating and flexible support structures includes one or more coil formation devices configurable to produce helical spring coils having a terminal convolution which extends beyond an end of the coil; a conveyor system having a plurality of flights slidably mounted upon a continuous track and connected to a chain and driven by an index driver, the flights being connected to a drive system which enables variable spacing between the flights so that the conveyor can be loaded with articles at one spacing interval and be unloaded at a different interval; a coil transfer machine which removes a row of coils from the conveyor and inserts the coils into an innerspring assembler; an innerspring assembler having first and second sets of coil-engaging dies in a parallel arrangement, each set of dies having an upper row positioned over a lower row, the dies being mounted upon carrier bars which are vertically t

Abstract: Machinery for automated manufacture of formed wire structures such as innerspring assemblies for mattresses and seating and flexible support structures includes one or more coil formation devices configured to produce generally helical spring coils having a terminal convolution which extends beyond an end of the coil; a conveyor system having a plurality of flights slidably mounted upon a continuous track and connected to a chain and driven by an index driver; a coil transfer machine which removes a row of coils from the conveyor and inserts the coils into an innerspring assembler; and an innerspring assembler. A coil forming block on a coiler machine has a cavity in which a terminal convolution of the coil is formed, and from which the coil is cut by a cutter which extends into the cavity.

Abstract: The invention includes linkage assemblies comprising coupled links with metallic contact surfaces with improved stiffness. The inventors found significant mechanical problems with all previous descriptions of metallic contact links sufficient to preclude their commercial use. These metallic contact links are a significant improvement over existing plastic ball and metal joint, or all plastic beads as found in the prior art. The invention includes methods providing these links and high friction couplings between them, as well as the linkage assemblies and flexible arms resulting from these processes.

Abstract: Machinery for automated manufacture of formed wire structures such as innerspring assemblies for mattresses and seating and flexible support structures includes one or more coil formation devices configurable to produce helical spring coils having a terminal convolution which extends beyond an end of the coil; a conveyor system having a plurality of flights slidably mounted upon a continuous track and connected to a chain and driven by an index driver, the flights being connected to a drive system which enables variable spacing between the flights so that the conveyor can be loaded with articles at one spacing interval and be unloaded at a different interval; a coil transfer machine which removes a row of coils from the conveyor and inserts the coils into an innerspring assembler; an innerspring assembler having first and second sets of coil-engaging dies in a parallel arrangement, each set of dies having an upper row positioned over a lower row, the dies being mounted upon carrier bars which are vertically t

Abstract: A thermal treatment system for supplying thermally conditioned or purified water for human or animal consumption, industrial processes, environmental containment, or removal of foreign species. The water purifier includes a heat exchanger for exchanging heat between outgoing thermally conditioned or purified water and incoming makeup water; a water heater is connected to the heat exchanger so as to receive pre-heated incoming makeup water, where the water heater subsequently heats the incoming preheated makeup water to a set-point temperature in the case of thermally conditioned water and for purified water also holds the water for a period of time sufficient to inactivate selected organisms to a predetermined level. The heat exchanger has one or more treated water outlets for supplying thermally conditioned or purified water at selected temperatures.

Abstract: Machinery for automated manufacture of formed wire structures such as innerspring assemblies for mattresses and seating and flexible support structures includes one or more coil formation devices configurable to produce generally helical spring coils having a terminal convolution which extends beyond an end of the coil; a conveyor system having a plurality of flights slidably mounted upon a continuous track and connected to a chain and driven by an index driver; a coil transfer machine which removes a row of coils from the conveyor and inserts the coils into an innerspring assembler; an innerspring assembler having first and second sets of coil-engaging dies in a parallel arrangement, each set of dies having an upper row positioned over a lower row, the dies being mounted upon carrier bars which are vertically translated within the innerspring assembler to diverge the upper and lower dies of a set to allow positioning of a row of uncompressed coils between the upper and lower dies, and to converge the upper a