Abstract: Methods and devices for removing cationic glutamate or anionic aluminum complexes from brain tissue by applying a voltage to the brain tissue.

Abstract: A method of adding an effective amount of reactive oxygen species (ROS) to a mixture of macrophages to induce VEGF production by the macrophages. The induced macrophages are then added to a graft material.

Abstract: Heating the hypothalamus, preferably by ultrasound, to cause the release of ?MSH in the brain.

Abstract: This invention relates to an implantable device that delivers an effective amounts of red light to the substantia nigra as a treatment for Parkinson's Disease (PD).

Abstract: This invention relates to an intervertebral motion disc having a height adjustable endplate.

Abstract: A UV probe capable of providing a Th2 immune environment for the treatment of back pain.

Abstract: Active immunization and a formulation for treating or preventing osteolysis caused by Wear Particles, comprising: a) a Th2 -inducing adjuvant, and b) Wear Particles.

Abstract: Irradiating osteolytic regions with UVB light.

Abstract: An intracranial, light-emitting implant for providing therapy to a patient having Alzheimer's Disease.

Abstract: Administering to a patient Type I interferon or viable cells induced to produce Type I Interferon preferably into an inflamed joint, such an interverebral disc, for example, is disclosed.

Abstract: Administering a buffy coat and immunoglobulin into a disc to induce the production of interleukin receptor antagonist protein IRAP within the disc is disclosed.

Abstract: An enhanced adipose tissue containing native adipose tissue and a concentrated amount of an active agent derived from adipose tissue, wherein the enhanced adipose tissue is preferably injected into the intervertebral disc of a patient suffering from degenerative disc disease.

Abstract: Administering an effective amount of adiponectin into an osteolytic region.

Abstract: A hydrocephalus shunt having an anti-inflammatory coating applied to at least the outside surface of the ventricular catheter. Such coatings are also applicable to other medical devices or implants.

Abstract: A hydrocephalus shunt has photocatalytic capabilities. The shunt is used to treat hydrocephalus by inserting into a human cranium a hydrocephalus shunt having a component having a surface. Thereafter, a reactive oxygen species is produced on the component surface. The component may be a catheter. The shunt may also include a light source.

Abstract: An implant comprises a photocatalytic layer on at least one surface. In some embodiments, the photocatalytic layer is a semiconductor oxide that is doped. According to some embodiments, the implant comprises a wave guide. According to some embodiments the implant comprises a light port. According to some embodiments, the implant comprises a reflective material on a surface of the waveguide. According to some embodiments the implant comprises a composite material comprising a first material that has a transmissivity when exposed to a predetermined wavelength of light and a second material that has photocatalytic activity when exposed to the predetermined wavelength of light. According to some embodiments the implant comprises a light source adapted to irradiate the photocatalytic surface.

Abstract: This invention relates to local administration of a bone-forming agent and at least one anti-resorptive agent to treat osteoporosis and related disorders.

Abstract: An intervertebral fusion device includes a body having a proximal portion along a major axis of the body and a distal portion along the major axis, and supporting means at the distal portion. The supporting means supports vertebrae in a distracted position while the vertebrae fuse. At least one of the body and the supporting means has a height distinct from a width, whereby the body or supporting means can distract vertebrae, between which the body or the supporting means has been placed, by rotation of the body or the supporting means about the major axis. A method of fusing vertebrae includes the steps of inserting between two vertebrae an intervertebral fusion device and rotating the body or the supporting means, whereby the vertebrae are supported in a distracted position while the vertebrae fuse.

Abstract: The present invention relates to injecting a cycline compound into a diseased intervertebral disc.

Abstract: The present invention relates to trans-capsularly administering into a diseased joint a high specificity antagonist selected from the group consisting of: i) an inhibitor of a pro-inflammatory interleukin; ii) an inhibitor of TNF-? synthesis; iii) an inhibitor of membrane-bound TNF-?; iv) an inhibitor of a natural receptor of TNF-?; v) an inhibitor of NO synthase, vi) an inhibitor of PLA2 enzyme; vii) an anti-proliferative agent; viii) an anti-oxidant; ix) an apoptosis inhibitor selected from the group consisting of EPO mimetic peptides, EPO mimetibodies, IGF-I, IGF-II, and caspase inhibitors, and x) an inhibitor of MMPs; and xi) an inhibitor of p38 kinase.