Abstract: Novel thyroid receptor ligands are provided having the general formula I wherein X, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12 and R13 are as defined herein. In addition, a method is provided for preventing, inhibiting or treating diseases or disorders associated with metabolic dysfunction or which are dependent upon the expression of a T3 regulated gene, wherein a compound as described above is administered in a therapeutically effective amount.

Abstract: This invention relates to novel compounds which are thyroid receptor ligands, preferably antagonists, and to methods for using such compounds in the treatment of cardiac and metabolic disorders, such as cardiac arrhythmias, thyrotoxicosis, subclinical hyperthyrodism and liver diseases.

Abstract: The invention provides compounds of formula I or a pharmaceutically acceptable ester, amide, solvate or salt thereof, including a salt of such an ester or amide, and a solvate of such an ester, amide or salt. The invention also provides the use of such compounds in the treatment or prophylaxis of a condition mediated by a thyroid receptor. Formula (I) wherein R1, R2, n, Y, Y?, R3, R4, W and R5 are as defined in the specification.

Abstract: This invention relates to novel compounds, which are thyroid receptor ligands, and to methods of preparing such compounds. In addition, a method is provided for preventing, inhibiting or treating diseases or disorders associated with metabolism dysfunction or which are dependent upon the expression of a T3 regulated gene, wherein a compound as described herein is administered in a therapeutically effective amount.

Abstract: This invention relates to novel compounds which are thyroid receptor ligands, preferably antagonists, and to methods for using such compounds in the treatment of cardiac and metabolic disorders, such as cardiac arrhythmias, thyrotoxicosis, subclinical hyperthyrodism and liver diseases.

Abstract: Novel thyroid receptor ligands are provided having the general formula I 1

Abstract: Polypeptide sequences for PERV-A receptors found on primate cells, including human, and the polynucleotides encoding those polypeptide receptor sequences are disclosed along with processes for using the PERV-A receptors in both in vitro and in vivo screening assays and models for agents that block viral infection. Also disclosed are processes for detecting the presence of PERV receptors in a tissue, blocking virus binding to receptors and protection of an animal, such as a human patient, from PERV infection. Antibodies that react with PERV receptors, vectors comprising the polynucleotides encoding such receptors and recombinant cells that express these receptors are also described.

Abstract: A process for absorbing oil and a particulate oil-absorbing composition are provided, which composition in dust form displays a low explosion hazard and a low flammability, but which after absorption of oil is flammable and entirely consumed when burned, the particles comprising as the major component at least 50% by weight hydrophobic cellulose pulp fibers blended with at least 30% up to 50% of an inorganic cellulose paper pulp filler.

Abstract: A process is provided for the absorption of organic liquids, particularly oil, using hydrophobic fibrous material prepared by impregnating fibrous material comprising cellulose fibers with a liquid resinous material selected from the group consisting of acrylate prepolymers and polymers, alkyd prepolymers and polymers, and polyester prepolymers and polymers in an amount to provide in the impregnated fibrous material from about 0.5 to about 30% by weight polyacrylate, polyalkyd or polyester, and then heating the impregnated fibrous material to convert the polymer or prepolymer by chemical reaction into a hydrophobic polymer rendering the fibrous material hydrophobic.