Patents by Inventor Thomas Erker

Thomas Erker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bumetanide Derivatives for the Therapy of Stroke and Other Neurological Diseases/Disorders Involving NKCCs
    Publication number: 20210163406
    Abstract: The present invention relates to bumetanide derivatives of formula (I) as well as pharmaceutical compositions comprising these compounds for use in the treatment or prevention of neurological diseases/disorders involving Na+-K+-20?-cotransporters (NKCCs), such as stroke, traumatic brain injury (TBI), spinal cord injury (SCI), peripheral nerve injury (PNI), brain edema, or glioma, and particularly for use in the treatment or prevention of stroke. The invention likewise relates to a method of treating or preventing a neurological disease or disorder involving an NKCC, such as stroke, TBI, SCI, PNI, brain edema, or glioma, the method comprising administering a compound of formula (I) to a subject in need thereof.
    Type: Application
    Filed: April 5, 2019
    Publication date: June 3, 2021
    Inventors: Thomas Erker, Philipp Schreppel, Dandan Sun
  • BUMETANIDE DERIVATIVES FOR THE THERAPY OF HYPERHIDROSIS
    Publication number: 20210022978
    Abstract: The present invention relates to bumetanide derivatives of formula (I) as well as pharmaceutical compositions comprising these compounds for use in the treatment or prevention of diseases/disorders involving Na+—K+2Cl?-cotransporters (NKCCs), and particularly for use in the treatment or prevention of hyperhidrosis.
    Type: Application
    Filed: April 5, 2019
    Publication date: January 28, 2021
    Inventors: Thomas Erker, Philipp Schreppel
  • Heteroaromatic chalcone derivatives and their medical use
    Patent number: 10280156
    Abstract: The present invention relates to heteroaromatic chalcone derivatives, particularly the compounds of formula (I) as described and defined herein, pharmaceutical compositions comprising these compounds, and their medical use, including their use in the treatment or prevention of cancer and, in particular, in the treatment or prevention of hematologic malignancies.
    Type: Grant
    Filed: August 28, 2015
    Date of Patent: May 7, 2019
    Assignees: Medizinische Universität Wien, Universität Wien
    Inventors: Katrina Vanura, Ulrich Jäger, Thomas Erker, Gerda Brunhofer-Bolzer
  • HETEROAROMATIC CHALCONE DERIVATIVES AND THEIR MEDICAL USE
    Publication number: 20170253583
    Abstract: The present invention relates to heteroaromatic chalcone derivatives, particularly the compounds of formula (I) as described and defined herein, pharmaceutical compositions comprising these compounds, and their medical use, including their use in the treatment or prevention of cancer and, in particular, in the treatment or prevention of hematologic malignancies.
    Type: Application
    Filed: August 28, 2015
    Publication date: September 7, 2017
    Inventors: Katrina VANURA, Ulrich JÄGER, Thomas ERKER, Gerda BRUNHOFER-BOLZER
  • VINYLOGOUS CHALCONE DERIVATIVES AND THEIR MEDICAL USE
    Publication number: 20130123367
    Abstract: The present invention relates to vinylogous chalcone derivatives, in particular the compounds of formula (I) as described and defined herein, pharmaceutical compositions comprising these compounds, and their medical use, including their use in the treatment or prevention of cancer, in particular malignant hematological diseases/disorders.
    Type: Application
    Filed: July 27, 2011
    Publication date: May 16, 2013
    Applicant: MEDIZINISCHE UNIVERSITAT WIEN
    Inventors: Thomas Erker, Gerda Brunhofer, Ulrich Jäger, Katrina Vanura, Verena Dirsch, Elke Heiss
  • PHARMACEUTICAL PREPARATIONS COMPRISING A COS RELEASING COMPOUND
    Publication number: 20130005739
    Abstract: The present invention relates to pharmaceutical compositions comprising a COS releasing compound according to formula (I) and to methods of preparing such compositions. Said pharmaceutical compositions may preferably be used for the treatment and/or the prevention of cardiovascular diseases.
    Type: Application
    Filed: December 28, 2010
    Publication date: January 3, 2013
    Applicants: LUDWIG BOLTZMANN CLUSTER FUER KARDIOVASKULAERE FORSCHUNG, UNIVERSITAET WIEN
    Inventors: Thomas Erker, Gerda Brunhofer, Christian Studenik, Bruno Podesser, Gabriela Pomper
  • Stilbene derivatives and their use in medicaments
    Publication number: 20070191627
    Abstract: The invention relates to stilbene derivatives of general formula (I), in which at least four of the substituents R1 to R6 do not represent hydrogen. The substituents are effective radical captors, anti-tumour active ingredients and selective cyclooxygenase-2 inhibitors.
    Type: Application
    Filed: August 9, 2004
    Publication date: August 16, 2007
    Inventors: Thomas Szekeres, Norbert Handler, Walter Jager, Arkadiusz Murias, Thomas Erker