Abstract: This filter element (1) comprises a filter medium (3) configured with an annular shape, having a central axis (X1) and forming inside a central channel (4) extending substantially axially, a first and a second end plates (5, 6), each plate covering one axial end of the filter medium (3) and being sealingly mounted on said axial end, the first end plate (5) having a central opening (7) substantially coaxial with the central axis (X1) and in fluid communication with the channel (4), and a central perforated rigid tube (9) that extends axially between the first and second end plates (5, 6) and having an inner perforated wall delimiting the central channel (4). The filter element (1) is designed to be placed in a filter housing (14) for forming a liquid filtering device (10), whereby a liquid to be filtered can flow along a liquid path through the filter medium (3) towards the channel (4) and out of the filter element (1) through the central opening (7).

Abstract: Compounds, such as compounds having Formula (I): wherein each variable is as described herein, that modulate the conversion of AMP to adenosine by 5?-nucleotidase, ecto, and compositions containing the compounds and methods for synthesizing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by 5?-nucleotidase, ecto is also provided.

Abstract: A filter element is provided and includes a filter medium having an axial channel, end plates each sealingly covering one axial end of the filter medium, one end plate having an opening in fluid communication with the channel, a hole arranged on the liquid path, not on the filter medium, and a closing member which is arranged in the hole and which is configured: to prevent liquid from flowing through the hole when the liquid pressure upstream the closing member is below a predetermined threshold to open at the threshold, to allow liquid to flow through the hole, and, after it has been opened, to remain open. A method is provided for checking the suitability of a filter element, at first use after a filter element change.

Abstract: This filter element (1) comprises a filter medium (3) configured with an annular shape, having a central axis (X1) and forming inside a central channel (4) extending substantially axially, a first and a second end plates (5, 6), each plate covering one axial end of the filter medium (3) and being sealingly mounted on said axial end, the first end plate (5) having a central opening (7) substantially coaxial with the central axis (X1) and in fluid communication with the channel (4), and a central perforated rigid tube (9) that extends axially between the first and second end plates (5, 6) and having an inner perforated wall delimiting the central channel (4). The filter element (1) is designed to be placed in a filter housing (14) for forming a liquid filtering device (10), whereby a liquid to be filtered can flow along a liquid path through the filter medium (3) towards the channel (4) and out of the filter element (1) through the central opening (7).

Abstract: A filter element includes: a filter medium having an axis and forming an axial channel; a first and a second end plates, each end plate covering one axial end of the filter medium and being sealingly mounted on the axial end, the first end plate having an central opening coaxial and in fluid communication with the channel; the filter element being designed to be placed in a filter housing for forming a liquid filtering device, whereby a liquid to be filtered can flow along a liquid path through the filter medium towards the channel and out of the filter element through the central opening. The filter element further includes further includes a detachable plug whose position can change from an attached position to a detached position.

Abstract: The invention relates to a fuel supply system for an internal combustion engine comprising:—a low pressure fuel pump (18);—a low pressure supply circuit (34) through which fuel is delivered by the low pressure pump (18) to one or several high pressure circuits (16), said low pressure supply circuit (34) comprising at least one delivery connection (36) for delivering fuel to the high pressure circuit(s) (16);—a pressure regulator (54) through which excess fuel from the low pressure supply circuit (34) is discharged through the pressure regulator (54) in a pump return circuit (56) which is fluidically connected to an input (20) of the low pressure pump (18) without passing through the fuel tank (14); characterized in that the pressure regulator (54) is located downstream of the delivery connection (36), and in that a fuel derivation circuit (60) is fluidically connected to the low pressure fuel supply circuit (34) downstream of the at least one delivery connection (36) to the high pressure circuit(s) and upstre

Abstract: A filter element is provided and includes a filter medium having an axial channel, end plates each sealingly covering one axial end of the filter medium, one end plate having an opening in fluid communication with the channel, a hole arranged on the liquid path, not on the filter medium, and a closing member which is arranged in the hole and which is configured: to prevent liquid from flowing through the hole when the liquid pressure upstream the closing member is below a predetermined threshold to open at the threshold, to allow liquid to flow through the hole, and, after it has been opened, to remain open. A method is provided for checking the suitability of a filter element, at first use after a filter element change.

Abstract: A filter element includes: a filter medium having an axis and forming an axial channel; a first and a second end plates, each end plate covering one axial end of the filter medium and being sealingly mounted on the axial end, the first end plate having an central opening coaxial and in fluid communication with the channel; the filter element being designed to be placed in a filter housing for forming a liquid filtering device, whereby a liquid to be filtered can flow along a liquid path through the filter medium towards the channel and out of the filter element through the central opening. The filter element further includes further includes a detachable plug whose position can change from an attached position to a detached position.

Abstract: In a fuel system for delivering pressurized fuel both to an internal combustion engine and to an exhaust installation, the fuel system includes two separate branches for delivering fuel to the internal combustion engine and to the exhaust installation, and includes a primary fuel pump delivering fuel to both branches of the fuel supply circuit. The primary fuel pump output is controllable independently of the engine speed. The pump output may be controlled such that the pressure of fuel in the fuel supply circuit depends on whether fuel is to be delivered to the exhaust installation. The fuel system may include a hydraulically controlled shut-off valve arrangement which is forced to switch depending on the pressure in the fuel supply circuit.

Abstract: In a fuel system for delivering pressurized fuel both to an internal combustion engine and to an exhaust installation, the fuel system includes two separate branches for delivering fuel to the internal combustion engine and to the exhaust installation, and includes a primary fuel pump delivering fuel to both branches of the fuel supply circuit. The primary fuel pump output is controllable independently of the engine speed. The pump output may be controlled such that the pressure of fuel in the fuel supply circuit depends on whether fuel is to be delivered to the exhaust installation. The fuel system may include a hydraulically controlled shut-off valve arrangement which is forced to switch depending on the pressure in the fuel supply circuit.

Abstract: The invention relates to a fuel supply system for an internal combustion engine comprising:—a low pressure fuel pump (18);—a low pressure supply circuit (34) through which fuel is delivered by the low pressure pump (18) to one or several high pressure circuits (16), said low pressure supply circuit (34) comprising at least one delivery connection (36) for delivering fuel to the high pressure circuit(s) (16);—a pressure regulator (54) through which excess fuel from the low pressure supply circuit (34) is discharged through the pressure regulator (54) in a pump return circuit (56) which is fluidically connected to an input (20) of the low pressure pump (18) without passing through the fuel tank (14); characterized in that the pressure regulator (54) is located downstream of the delivery connection (36), and in that a fuel derivation circuit (60) is fluidically connected to the low pressure fuel supply circuit (34) downstream of the at least one delivery connection (36) to the high pressure circuit(s) and upstre