Patents by Inventor Thomas H. Fraser

Thomas H. Fraser has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4629792
    Abstract: An in vitro enzymatic process which efficiently converts (+,-)-tropicamide to essentially pure (+), (-)-tropicamide O-.beta.-D-glucuronide. This product is then separated, advantageously, into the novel compounds (+)-tropicamide O-.beta.-D-glucuronide and (-)-tropicamide O-.beta.-D-glucuronide. The products disclosed herein absorb ultraviolet light, and, thus, can be incorporated into suitable plastic films which are then useful for screening out harmful ultraviolet radiation for the protection of packaged goods. Also, the products can be used to protect the skin against burning by sunlight.
    Type: Grant
    Filed: September 9, 1985
    Date of Patent: December 16, 1986
    Assignee: Repligen Corporation
    Inventors: Walter C. Herlihy, Thomas H. Fraser
  • Patent number: 4588686
    Abstract: An in vitro enzymatic process which efficiently converts (+,-)-tropicamide to essentially pure (+), (-)-tropicamide O-.beta.-D-glucuronide. This product is then separated, advantageously, into the novel compounds (+)-tropicamide O-.beta.-D-glucuronide and (-)-tropicamide O-.beta.-D-glucuronide. The products disclosed herein absorb ultraviolet light, and, thus, can be incorporated into suitable plastic films which are then useful for screening out harmful ultraviolet radiation for the protection of packaged goods. Also, the products can be used to protect the skin against burning by sunlight.
    Type: Grant
    Filed: January 31, 1984
    Date of Patent: May 13, 1986
    Assignee: Repligen Corporation
    Inventors: Walter C. Herlihy, Thomas H. Fraser
  • Patent number: 4443608
    Abstract: An in vitro enzymatic process which efficiently converts (+,-)-tropicamide to essentially pure (+), (-)-tropicamide O-.beta.-D-glucuronide. This product is then separated, advantageously, into the novel compounds (+)-tropicamide O-.beta.-D-glucuronide and (-)-tropicamide O-.beta.-D-glucuronide. The products disclosed herein absorb ultraviolet light, and, thus, can be incorporated into suitable plastic films which are then useful for screening out harmful ultraviolet radiation for the protection of packaged goods. Also the products can be used to protect the skin against burning by sunlight.
    Type: Grant
    Filed: May 24, 1982
    Date of Patent: April 17, 1984
    Assignee: Repligen Corporation
    Inventors: Walter C. Herlihy, Thomas H. Fraser
  • Patent number: 4443539
    Abstract: A process for expression of the gene for bovine growth hormone in the yeast Saccharomyces cerevisiae. Bovine growth hormone can be used to increase milk production in cows.
    Type: Grant
    Filed: June 8, 1981
    Date of Patent: April 17, 1984
    Assignee: The Upjohn Company
    Inventors: Thomas H. Fraser, Barbara J. Bruce
  • Patent number: 4430428
    Abstract: A process for expression of a gene, foreign to the host organism, coding for a protein in a suitable vehicle which comprises taking said gene and fusing it in the correct orientation relative to a transcriptional initiation region present in said vehicle, and inserting said vehicle into a eukaryotic host. Via the subject process, the gene for chicken ovalbumin is expressed in the yeast Saccharomyces cerevisiae. Chicken ovalbumin can be used in the food, i.e., baking, industry and also as a protein supplement for animals.
    Type: Grant
    Filed: December 7, 1981
    Date of Patent: February 7, 1984
    Assignee: The Upjohn Company
    Inventors: Thomas H. Fraser, Barbara J. Bruce