Abstract: A body tissue graft for use in a patient includes a frame structure made of a first elastic material, a covering of a second elastic material on the frame structure, the covering substantially filling openings in the frame structure, and a connector connected to the frame structure. Projections are secured to the connector structure. The projections facilitate attachment of the tubular graft in a patient by securing the graft to the body tissue with which the graft is employed. The connector selectively circumferentially expands and the projections selectively circumferentially expand. This may be done using an inflatable balloon to circumferentially expand the projections. A restraining member may be provided to restrain the projections in a cone shape so that an end of the graft may be used to open an aperture through a side wall of existing body organ tubing and a portion of the projections may enter the aperture.

Abstract: Connectors are provided for attaching flexible tubular grafts to the body organ tubing of a patient at oblique angles. The connector structures may be formed from two elongated members connected by a series of struts. Wire hooks welded to the connector may be used to engage the graft and the body organ tubing when the connector is used to attach the graft to the body organ tubing. The struts are bendable so that the elongated members can be compressed toward each other when it is desired to install a graft by placing the graft and the connector in a delivery tube. When the connector and graft are released from the delivery tube at the installation site, at least the open end of the connector adjacent to the body organ tubing has an oval shape for insertion into and attachment to an oval aperture in the body organ tubing.

Abstract: A filter includes a center layer of carbon cloth interposed between two layers of filter material whose edges are welded together to provide not only a filter edge substantially free of carbon particles, but also an effective barrier to the migration of carbon particles from the filter's interior to its exterior. A filter pouch, encapsulating the carbon filter, includes a layered structure welded together proximate its edges. The filter pouch is also suitable for use with a desiccant filter.

Abstract: Methods and apparatus for delivering and installing a new Length of tubing between two sections of a patient's existing body organ tubing and at least partly outside of that existing structure. For example, the new length of tubing may be for the purpose of providing the patient with a coronary bypass. The new tubing may be an artificial graft, a natural graft (harvested elsewhere from the patient), or both. The new tubing is delivered to and installed at the operative site primarily by working through the patient's existing tubular body organ structure. This avoids the need for any significant surgery on the patient. The artificial grafts may have shapes other than tubular. Certain procedural and apparatus aspects of the invention have uses other than in connection with grafting in general or tubular grafting in particular.

Abstract: Connectors are provided for making connections between tubular conduits in medical procedures such as those involving treatment of a patient's circulatory system. The connectors are variously configured for making end-to-side or end-to-end connections of tubular conduits. One of the tubular conduits may be a graft conduit, which can be artificial conduit, natural conduit, or a combination of both. The connectors for making end-to-side connections can be generally T-shaped or L-shaped. Various portions of the connectors can attach to the inside or outside of the associated conduit, depending on the connector configuration that is selected.

Abstract: A tubular artificial graft for attachment to a patient's tubular body tissue has an initially radially relatively small connector structure adjacent each of its ends. The initial relatively small size of each connector structure facilitates insertion of that portion of the graft into the body tissue to which that connector structure is to make a connection. After a connector structure is properly positioned relative to the body tissue, the connector structure is radially enlarged to connect the graft to the body tissue. The connection is preferably both a mechanical and a fluid-tight connection.

Abstract: Methods and apparatus are provided for attaching grafts of tubing between sites in a patient's body via the patient's existing arteries and veins. Grafts may be held in place during graft delivery using a partially inflated proximal balloon and a partially inflated distal balloon which frictionally engage axially spaced portions of the graft (e.g., pronged attachment rings that pierce the graft adjacent its ends). After aligning the distal end of the graft with the distal attachment site, the distal balloon may be further inflated to help attach the distal end of the graft to the distal attachment site (e.g., by driving the prongs of the distal attachment ring into the distal attachment site). The proximal balloon may then be inflated to attach the proximal end of the graft to the proximal attachment site. The insertion instrument allows the distance between the distal and proximal balloons to be adjusted, thereby accommodating grafts of various lengths.

Abstract: A bodily fluid filter has an elastic tubular framework and a plurality of filter filaments extending from the surface of the tubular framework in toward the longitudinal axis to trap objects to be filtered. The elastic framework is deformable to facilitate deployment and removal, but resumes its operational shape once deployed. The filter can be installed intralumenally and/or remotely if desired.

Abstract: Catheter and method of manufacturing such catheter. The catheter includes an elongate shaft having an interior lumen extending therethrough. The interior surface of the lumen is geometrically configured to reduce friction and increase catheter performance. Additionally, the geometrically configured inside surface allows dye or blood to perfuse past the distal end of the catheter when engaged in the coronary artery. The catheter may also include a geometrically configured outer surface at its distal end having perfusion channels to allow blood to perfuse past the distal end of the catheter during catheter engagement.

Abstract: Guide catheter incorporating a braidless construction having increased performance characteristics for catheterization procedures. The guide catheter may include a tracking wire, inner or outer guide for positioning the guide catheter within the patient's vascular system.

Abstract: An intraluminal guidewire for use in medical procedures in general, and cardiovascular procedures in particular. A core wire is formed as the inner member of the guidewire. A distal helical coil is fixedly attached to the distal end of the core wire. A proximal helical coil is fixedly attached to the core wire proximally of the distal coil. The proximal end of the distal coil and the distal end of the proximal coil can be fixedly mounted in spaced relation on a flexible spacer sleeve. The two coils can be of different materials, such as stainless steel and gold, having significantly differing degrees of radiopacity. The sleeve can be a third degree of radiopacity, preferably selected to show a dark spot on a fluoroscope. The coils can be attached to the core wire by a flexible adhesive.

Abstract: Guide catheter unibody and method for manufacturing such a catheter. In one preferred embodiment, the present invention is a unibody guide catheter for use in percutaneous transluminal angioplasty procedures. The catheter includes a base layer and a structural layer formed over the base layer. The structural layer includes strands which cross at a plurality of points, the strands being attached together for structural integrity at a substantial number of points where they cross. The structural layer may be at least partially embedded in the base layer. Additionally, a cover layer is formed over the structural layer.

Abstract: Catheter and method of manufacturing such catheter. The catheter includes an elongate shaft having an interior lumen extending therethrough. The interior surface of the lumen is geometrically configured to reduce friction and increase catheter performance. Additionally, the geometrically configured inside surface allows dye or blood to perfuse past the distal end of the catheter when engaged in the coronary artery. The catheter may also include a geometrically configured outer surface at its distal end having perfusion channels to allow blood to perfuse past the distal end of the catheter during catheter engagement.

Abstract: Guide catheter exchange device and method of exchanging a guide catheter. The guide catheter exchange device includes a magnetically responsive segment located on a proximal end for maintaining a previously placed guide wire in position across a stenosis, while performing a guide catheter exchange procedure. The guide catheter exchange device allows a guide catheter exchange procedure to be performed by a solo physician.

Abstract: A pleatable filter media, suitable for a use in a respirator for humans, is disclosed comprising a filter material including a meltblown polymeric material, such as polypropylene. A laminate construction is disclosed for the filter material comprising a plurality of layers of the meltblown polypropylene laminated together with adhesive. The filter media is preferably glassless. Protective layers enclose the layers of meltblown polypropylene. Methods of manufacture of pleated material are disclosed wherein the adhesive between the layers is extruded in a particular pattern to provide increased stiffness in the machine direction of the pleated filter media. Methods of manufacture are also disclosed wherein the filter media is pleated before the adhesive has cured, and the adhesive is then permitted to cure while the filter media is maintained in the pleated state.