Abstract: Disclosed herein are novel lipids that can be used in combination with other lipid components, such as helper lipids, structural lipids, and cholesterols, to form lipid nanoparticles for delivery of therapeutic agents, such as nucleic acids (e.g., circular polynucleotides), both in vitro and in vivo.

Abstract: Disclosed herein are novel lipids that can be used in combination with other lipid components, such as helper lipids, structural lipids, and cholesterols, to form lipid nanoparticles for delivery of therapeutic agents, such as nucleic acids (e.g., circular polynucleotides), both in vitro and in vivo.

Abstract: A stab for use in a plug-in assembly includes a stab piece and a lug. The stab piece includes one or more contact arms configured to engage a bus bar, and a base portion coupled to the one or more contact arms. The base portion is configured to be coupled to a stab shaft for rotating the stab about a rotational axis to transition the stab from a retracted position to an extended position. The lug is coupled to the stab piece and configured to receive wire for transmitting power from the bus bar to an electrical component. The lug is configured to be deformed around the wire to hold the wire when a crimping force is applied to the lug. The lug is configured to hold the wire at a position approximately centered on a rotational axis of the stab shaft when the lug is deformed by the crimping force.

Abstract: A stab for use in a plug-in assembly includes a stab piece and a lug. The stab piece includes one or more contact arms configured to engage a bus bar, and a base portion coupled to the one or more contact arms. The base portion is configured to be coupled to a stab shaft for rotating the stab about a rotational axis to transition the stab from a retracted position to an extended position. The lug is coupled to the stab piece and configured to receive wire for transmitting power from the bus bar to an electrical component. The lug is configured to be deformed around the wire to hold the wire when a crimping force is applied to the lug.

Abstract: A chain and sprocket system includes a plurality of chains and sprockets. The system includes a central shaft, two chains, and two identical sprockets. Although the two sprockets have identical size, shape, and features, they can be assembled onto the central shaft in different orientations. These orientations are achieved by rotating one sprocket with respect to the other. Assembling one sprocket onto the shaft in a different orientation from a second sprocket results in a system where the outer sprocket teeth of one sprocket are phased with respect to the outer sprocket teeth of the other sprocket. In this way, a phased chain and sprocket assembly is composed of identical sprockets, which eases manufacture and assembly.

Abstract: A chain tensioner comprising an integrated tensioner body and tensioner arm. The tensioner body includes a fluid reservoir and a tensioner bore. The tensioner arm includes a pivot bore with a pivot pin disposed in the pivot bore to pivotally mount the tensioner arm. A check valve connecting the fluid reservoir to the tensioner bore permits fluid to flow into the tensioner bore, but not into the fluid reservoir. A plunger is slidably fitted into the tensioner bore and biased out from the tensioner bore by the fluid pressure in the tensioner bore. As a result, the plunger is forced against a fixed boss, causing rotational movement of the tensioner body and tensioner arm.

Abstract: A self-guiding chain assembly includes a silent chain with inner and outer links having depending toes. Traditional guide links are replaced by inverted tooth outer links with a crotch of lesser height than the crotch of the inner links. The outer links perform the self-guiding function and act to maintain the chain on the sprockets. The chain has particular application in engine timing systems that utilize phased chains and sprockets.

Abstract: A camshaft (426) has a vane (460) secured to an end thereof for non-osciling rotation therewith. The camshaft also carries a sprocket (432) which can rotate with the camshaft but which is oscillatable with respect to the camshaft. The vane has opposed lobes (460a, 460b) which are received in opposed recesses (432a, 432b), respectively, of the sprocket. The recesses have greater circumferential extent than the lobes to permit the vane and sprocket to oscillate with respect to one another, and thereby permit the camshaft to change in phase relative to a crankshaft whose phase relative to the sprocket is fixed by virtue of a chain drive extending therebetween.