Abstract: Compounds, compositions and method of using these compounds are disclosed for treating a disease or disorder in which it is desirable to inhibit BAX, such as a cardiovascular disease or disorder.

Abstract: The invention relates to a speed-changing shearing or forming active element insert which is designed to be detachably connected to an active element receptacle of a machine tool, the speed-changing shearing or forming active element insert having a speed-changing unit which is in the form of a hydraulic force/distance transducer, the force/distance transducer comprising a housing, the housing interior of which is supplied with a hydraulic fluid, and the force/distance transducer comprising a first piston which is in oo contact with the hydraulic fluid via one piston end and a second piston which is in contact with the hydraulic fluid via one piston end and the cross-sectional area of which is smaller than the cross-sectional area of the first piston. The invention also relates to the use of the speed-changing changing shearing or forming active element insert in a machine tool.

Abstract: A closed dual-bladder wave energy system that is capable of capturing a continuous supply of energy derived from wave movements for nearshore implementations. Rather than employing an onshore bladder in communication with an offshore bladder, and rather than focusing on capturing more incremental potential energy derived from tidal movement, the system accomplishes continuous captures potential energy from waves via a dual-bladder system employed offshore. Fluid within the system translates between a first offshore bladder and a second offshore bladder based on a pressure differential between a crest and a trough of a wave external to the system. By utilizing compliant bladders, the system is capable of capturing energy even during inclement weather conditions without the risk of faults resulting from strong waves. As such, the system provides for the efficient and effective capture of potential energy from waves in any weather condition and in any water environment that experiences waves.

Abstract: A wave energy collection and conversion system that uses a compliant capture mechanism to enable the collection of wave energy over extensive distances without introducing damaging forces onto the collection structure. The system includes a flexible membrane in contact with or submerged under water, a plurality of power generation devices positioned on a sea floor, and lines that connect the flexible membrane to the power generation devices. The power generation devices each include a self-reeling mechanism and a turbine. As wave energy pushes the flexible membrane, the lines are reeled into and out of the corresponding power generation device(s). Rotation of the shaft, in turn, rotates a gear and rotator of the turbine, thus harnessing energy derived from the wave motion.

Abstract: The invention provides a method for providing a strong link between a Subject and a cryptographic public/private key pair. The proposed Subject device and key distribution algorithm is less prone to man-in-the middle attacks as comparable known algorithms, thereby inherently strengthening the trustworthiness of any digital signature made with a private key distributed to a user in accordance with the proposed method. The invention additionally enables distribution of authentication factors over unsecure channels and reducing the need of sensitive information transmission by at the same time augmenting security for finally associating a generated public/private key pair to a Subject and using it for signature creation purposes.

Abstract: The invention relates to a method for operating a motor vehicle (1) which has at least one electric machine (7) which can be/is operatively connected to at least one driven wheel (6) of the motor vehicle (1), and a safety device (13) which is assigned to a driven wheel (6), is independent of the electric machine (7) and when necessary applies a positive or negative torque to the driven wheel (6), wherein the electric machine (7) is operated by an inverter (8). There is provision that the inverter (8) is monitored for incorrectly set torques, and that the safety device (13) is actuated as a function of a detected incorrect torque.

Abstract: A wave energy collection and conversion system that uses a compliant capture mechanism to enable the collection of wave energy over extensive distances without introducing damaging forces onto the collection structure. The system includes a flexible membrane in contact with or submerged under water, a plurality of power generation devices positioned on a sea floor, and lines that connect the flexible membrane to the power generation devices. The power generation devices each include a self-reeling mechanism and a turbine. As wave energy pushes the flexible membrane, the lines are reeled into and out of the corresponding power generation device(s). Rotation of the shaft, in turn, rotates a gear and rotator of the turbine, thus harnessing energy derived from the wave motion.

Abstract: A closed system that captures energy derived from the head differential rather than open-water flows velocities while reducing potential environmental damages and costly maintenance due to bio-fouling. This energy density available in a tidal range is increased substantially via convergent “nozzles” to produce an optimal speed for power generations with the turbine sections, thereby significantly increasing the tidal energy captured by this system, even at sites where tidal energy is low (e.g., small to medium tide ranges, such as found along the East and Gulf Coasts of the United States).

Abstract: A closed system that captures energy derived from the head differential rather than open-water flows velocities while reducing potential environmental damages and costly maintenance due to bio-fouling. This energy density available in a tidal range is increased substantially via convergent “nozzles” to produce an optimal speed for power generations with the turbine sections, thereby significantly increasing the tidal energy captured by this system, even at sites where tidal energy is low (e.g., small to medium tide ranges, such as found along the East and Gulf Coasts of the United States).

Abstract: The invention provides a method for providing a strong link between a Subject and a cryptographic public/private key pair. The proposed Subject device and key distribution algorithm is less prone to man-in-the middle attacks as comparable known algorithms, thereby inherently strengthening the trustworthiness of any digital signature made with a private key distributed to a user in accordance with the proposed method. The invention additionally enables distribution of authentication factors over unsecure channels and reducing the need of sensitive information transmission by at the same time augmenting security for finally associating a generated public/private key pair to a Subject and using it for signature creation purposes.

Abstract: The invention relates to a speed-changing shearing or forming active element insert which is designed to be detachably connected to an active element receptacle of a machine tool, the speed-changing shearing or forming active element insert having a speed-changing unit which is in the form of a hydraulic force/distance transducer, the force/distance transducer comprising a housing, the housing interior of which is supplied with a hydraulic fluid, and the force/distance transducer comprising a first piston which is in oo contact with the hydraulic fluid via one piston end and a second piston which is in contact with the hydraulic fluid via one piston end and the cross-sectional area of which is smaller than the cross-sectional area of the first piston. The invention also relates to the use of the speed-changing changing shearing or forming active element insert in a machine tool.

Abstract: A measuring arrangement with a measuring cell for detecting a process parameter and a housing, surrounding the measuring cell at least radially, with the measuring cell being arranged in the axial direction at the front in the housing and a space between the measuring cell and the housing being sealed with a seal from the penetration of process medium, with the seal showing at least a first sealing element radially surrounding a measuring cell and a second sealing element radially surrounding the measuring cell, the second sealing element being distanced from the first sealing element in the axial direction and arranged in front thereof, and the housing showing at least one first section extending in the axial direction and at least one second section arranged thereat and extending in the radial direction between the sealing elements.

Abstract: A measuring arrangement with a ceramic measuring cell and a metal process connection for connecting the measuring cell to a measuring environment, with the measuring cell being fastened in the process connection without gaskets and in a diffusion-resistant fashion, with the measuring cell being fastened at a ceramic ring, which is arranged at a metal ring for fastening in the process connection.

Abstract: A measuring arrangement with a measuring cell for detecting a process parameter and a housing, surrounding the measuring cell at least radially, with the measuring cell being arranged in the axial direction at the front in the housing and a space between the measuring cell and the housing being sealed with a seal from the penetration of process medium, with the seal showing at least a first sealing element radially surrounding a measuring cell and a second sealing element radially surrounding the measuring cell, the second sealing element being distanced from the first sealing element in the axial direction and arranged in front thereof, and the housing showing at least one first section extending in the axial direction and at least one second section arranged thereat and extending in the radial direction between the sealing elements.

Abstract: The invention relates to a method for operating a motor vehicle (1) which has at least one electric machine (7) which can be/is operatively connected to at least one driven wheel (6) of the motor vehicle (1), and a safety device (13) which is assigned to a driven wheel (6), is independent of the electric machine (7) and when necessary applies a positive or negative torque to the driven wheel (6), wherein the electric machine (7) is operated by an inverter (8). There is provision that the inverter (8) is monitored for incorrectly set torques, and that the safety device (13) is actuated as a function of a detected incorrect torque.

Abstract: A nut (1) having an internal thread (2), an external contour, with a design that is suitable for transmitting a tightening torque to the nut (1) and at least one first surface area (7) essentially oriented in the axial direction (A) of the nut (1), wherein the first surface area (7) comprises at least one cutting mold (5).

Abstract: Provided is a measuring arrangement system operative for measuring a physical and/or chemical process variable of a process medium, which is held in a container, having a measuring device with a process connection and a sensor housing attached to it, such that the process connection comprises a measuring cell housing with a measuring cell, wherein a circumferential web, which divides the circumferential surface into a first and second circumferential section, is provided on the circumferential surface of the measuring cell housing; the process connection comprising a union nut with an inside thread and interior ring stop; and a tubular flange having first and second ends, having on its first end an outside thread, designed to correspond to the inside thread of the union nut, such that the circumferential web is designed so the measuring cell housing can be clamped between the flange and the union nut in two different directions.

Abstract: A sensor device and a method for the geoelectrical prospecting of the location, the (stratographic) arrangement, and the course of raw mineral deposits and of the adjoining rock delimiting these deposits, particularly in the continuous working of the mineral deposits, having a sensor head whose front surface forms the sensor measuring surface, and at least one electrode. The sensor head can make contact with a ground surface, and a central electrode and a plurality of outer electrodes distributed geometrically uniformly around the central electrode are arranged on the sensor measuring surface, the central electrode and the outer electrodes being electrically conductive and electrically separated from one another.

Abstract: A measuring arrangement with a ceramic measuring cell and a metal process connection for connecting the measuring cell to a measuring environment, with the measuring cell being fastened in the process connection without gaskets and in a diffusion-resistant fashion, with the measuring cell being fastened at a ceramic ring, which is arranged at a metal ring for fastening in the process connection.