Abstract: The invention provides methods for the identification of genes and their encoded proteins involved in the susceptibility to proliferative disorders, including cancer, using a tumor host range mutant virus (T-HR mutant). In addition, the invention provides methods for the diagnosis of abnormally proliferating cells in a subject, using a T-HR mutant. Furthermore, the T-HR mutants of the invention can also be used to kill cancer cells.

Abstract: The invention features a novel T-HR mutant virus, new primary cellular targets for DNA tumor viruses, such as Taz, as well as cellular factors, such as Death Inducer with SAP Domain (DIS) polypeptides, that interact with these primary targets. In addition, the invention encompasses DIS nucleic acid and amino acid sequences. The compounds described herein may be used in methods for diagnosing and treating patients having proliferative disorders, such as cancers.

Abstract: A method for increasing the percentage of mammalian offspring of either sex which comprises contacting a semen sample with an antibody specific for the spermatozoa determinative of one sex and separating said spermatozoa from spermatozoa determinative of the other sex, said antibody being bound to a non-porous magnetic bead support having a diameter of 0.1 to 2 microns.

Abstract: A method for increasing the percentage of mammalian offspring of either sex which comprises contacting a semen sample with an antibody specific for the spermatozoa determinative of one sex and separating said spermatozoa from spermatozoa determinative of the other sex, said antibody being bound to a non-porous magnetic bead support having a diameter of 0.1 to 2 microns.

Abstract: The invention features the use of Sal2 nucleic acids and proteins in methods for treating patients having proliferative disorders, such as cancers, involving mutations in a Sal2 nucleic acid sequence and in the protein that it encodes. In addition, these treatment methods may also be used for patients having a mutation in a nucleic acid sequence encoding a protein that interacts with Sal2 or that functions in a signaling pathway involving Sal2. Furthermore, Sal2 may be used as an anti-viral agent that interferes with the ability of a DNA tumor virus to replicate and disseminate in a cell.

Abstract: The invention features the analysis of Sal2 nucleic acids and proteins for diagnosing and treating patients having proliferative disorders, including cancer, involving mutations in a Sal2 gene and encoded protein. The invention also includes transgenic and knockout mice including Sal2 nucleic acids or proteins and mutants thereof. Furthermore, the invention features a method of killing cells carrying a Sal2 alteration using a T-HR mutant.

Abstract: The invention provides methods for the identification of genes and their encoded proteins involved in the susceptibility to proliferative disorders, including cancer, using a tumor host range mutant virus (T-HR mutant). In addition, the invention provides methods for the diagnosis of abnormally proliferating cells in a subject, using a T-HR mutant. Furthermore, the T-HR mutants of the invention can also be used to kill cancer cells.

Abstract: A method for increasing the percentage of mammalian offspring of either sex which comprises contacting a semen sample with an antibody specific for the spermatozoa determinative of one sex and separating said spermatozoa from spermatozoa determinative of the other sex, said antibody being bound to a non-porous magnetic bead support having a diameter of 0.1 to 2 microns.

Abstract: An assay method is provided to easily and quickly detect the presence of organisms capable of being cultured, such as bacteria, characterized by antibody capture of the organism of interest by use of specialized magnetic beads, incubation of the captured cells to form colonies; removal of material from the colonies with a colony lift membrane; and detection of the colony material on the membrane sheet by use of labeled antibodies, PCR or nucleic acid probes.

Abstract: An assay method is provided to easily and quickly detect the presence of organisms capable of being cultured, such as bacteria, characterized by antibody capture of the organism of interest by use of specialized magnetic beads, incubation of the captured cells to form colonies; removal of material from the colonies with a colony lift membrane; and detection of the colony material on the membrane sheet by use of labeled antibodies, PCR or nucleic acid probes.

Abstract: An assay method is provided to quickly detect the presence of Listeria strains in samples, characterized by the use of antibodies to selectively capture the peptidoglycan and teichoic acid components of the listeriae bacterial cell wall.

Abstract: A system for public display of ultraviolet radiation levels wherein said radiation is collected and measured by one or several optical collectors or sensor assemblies at remote sensing stations. Optical fibers receive and then convey the radiation of the sun through a filter and onto a photovoltaic sensor, measuring the intensity of the ultraviolet radiation. An electrical signal proportional to the ultraviolet radiation is produced with the signal being amplified and either used directly as analog data or converted to a digital signal for the modulation of a radio transceiver. The signal is transmitted to a transceiver of a central data processing station, where it is processed. The processed signal is retransmitted to a receiver in which the processed signal carrier is demodulated and the signal fed to a display station providing the level of exposure to the public.