Abstract: Methods and systems determine risks of deterioration of hospitalized or other monitored or cared-for patients, for example in a treatment facility such as a hospital or under home-health care. In embodiments, a warning or other instruction is issued to medical professionals to alert them that certain patients have moderate or high risk of transfer to a higher level of care or should be monitored more frequently. A medical professional can accept alerts regarding prediction of deterioration, causing a prophylactic transfer or increased monitoring, or a transfer or monitoring order can occur automatically. Data relating to all patients in a unit of a medical facility can be viewed including warnings relating to risk of transfer or deterioration, so that a medical facility can intervene prior to an event such as a cardiac event and/or plan to accommodate patients at higher levels of care or monitoring.

Abstract: Methods and systems determine risks of deterioration of hospitalized or other monitored or cared-for patients, for example in a treatment facility such as a hospital or under home-health care. In embodiments, a warning or other instruction is issued to medical professionals to alert them that certain patients have moderate or high risk of transfer to a higher level of care or should be monitored more frequently. A medical professional can accept alerts regarding prediction of deterioration, causing a prophylactic transfer or increased monitoring, or a transfer or monitoring order can occur automatically. Data relating to all patients in a unit of a medical facility can be viewed including warnings relating to risk of transfer or deterioration, so that a medical facility can intervene prior to an event such as a cardiac event and/or plan to accommodate patients at higher levels of care or monitoring.

Abstract: This invention relates to the formulations and methods for use to sanitize and protect goblet secretory cells, which produce mucus, as well as the skin cells and hair within the nasal passage to inhibit bacterial, fungal and viral infections. A novel nasal spray composition of the invention includes an organosilane compound, C23H52ClNO3Si cross-linked to a botanical, Thymol, C10H14O, a steroid, dexamethasone, C22H29FO5, a polyol stabilizing agent and a nonionic surfactant that adheres to mucosa, skin cells and hair in the nasal passages. The composition creating a 12-24 hour, and up to a 48-hour bio-barrier to inhibit an infection from bacteria fungi, and viruses.

Abstract: Fabric treatment compositions are described that provide three functions to the textiles to which they are applied: sanitizing (killing microbes therein or thereon), conditioning or softening, and providing a residual antimicrobial effect to prevent immediate reinfection after treatment. Such trifunctional, or three-in-one, fabric treatments employing organosilane compounds, nonionic and cationic surfactants, a botanical (Thymol) and cationic fabric conditioners, and their use as microbicidal and microbiostatic agents, and fabric conditioners and softeners are also described.

Abstract: Methods and systems determine risks of deterioration of hospitalized or other monitored or cared-for patients, for example in a treatment facility such as a hospital or under home-health care. In embodiments, a warning or other instruction is issued to medical professionals to alert them that certain patients have moderate or high risk of transfer to a higher level of care or should be monitored more frequently. A medical professional can accept alerts regarding prediction of deterioration, causing a prophylactic transfer or increased monitoring, or a transfer or monitoring order can occur automatically. Data relating to all patients in a unit of a medical facility can be viewed including warnings relating to risk of transfer or deterioration, so that a medical facility can intervene prior to an event such as a cardiac event and/or plan to accommodate patients at higher levels of care or monitoring.

Abstract: Methods and systems determine risks of deterioration of hospitalized or other monitored or cared-for patients, for example in a treatment facility such as a hospital or under home-health care. In embodiments, a warning or other instruction is issued to medical professionals to alert them that certain patients have moderate or high risk of transfer to a higher level of care or should be monitored more frequently. A medical professional can accept alerts regarding prediction of deterioration, causing a prophylactic transfer or increased monitoring, or a transfer or monitoring order can occur automatically. Data relating to all patients in a unit of a medical facility can be viewed including warnings relating to risk of transfer or deterioration, so that a medical facility can intervene prior to an event such as a cardiac event and/or plan to accommodate patients at higher levels of care or monitoring.

Abstract: A method for treating human or animal skin, hands, feet, hair or nails to eliminate or reduce the number of microorganisms thereon by topical application of an aqueous formulation comprising antimicrobial organosilane quaternary ammonium compounds and benzalkonium chloride of the quaternary group, which provides antimicrobial and antiseptic activity. The method prevents reinfection for at least 12, preferably 24 and most preferably at least 60 hours. The formulation may further comprise methyl anthranilate, which performs the dual functions of fragrance (grape fragrance) and biocidal agent. The formulation may further comprise other compatible inert but desirable ingredients such as moisturizers, color and fragrance.

Abstract: Methods of applications of organosilanes optionally having a nonhydrolyzable organic group, but having one or more hydrolyzable groups, with a polyol containing at least three hydroxy groups, where any two of the hydroxy groups are separated by at least three intervening atoms by aerosolization of droplets between 0.5-8 microns are disclosed and an improved formulation comprising adding a nonionic wetting agent are disclosed. An improved aerosolization application technique and the improved formulation provide for smaller droplet size and better coverage of substrates to which the organosilanes are applied. The improved formulation has increased affinity, reduces surface tension and therefore can covalently bond more quickly. A method of treating a substrate, and the treated substrate so formed, by contacting the substrate with the improved formulation for a period of time sufficient for treatment of the substrate are disclosed.

Abstract: Methods of applications of organosilanes optionally having a nonhydrolyzable organic group, but having one or more hydrolyzable groups, with a polyol containing at least three hydroxy groups, where any two of the hydroxy groups are separated by at least three intervening atoms by aerosolization of droplets between 0.5-8 microns are disclosed and an improved formulation comprising adding a nonionic wetting agent are disclosed. An improved aerosolization application technique and the improved formulation provide for smaller droplet size and better coverage of substrates to which the organosilanes are applied. The improved formulation has increased affinity, reduces surface tension and therefore can covalently bond more quickly. A method of treating a substrate, and the treated substrate so formed, by contacting the substrate with the improved formulation for a period of time sufficient for treatment of the substrate are disclosed.

Abstract: Methods of applications of organosilanes optionally having a nonhydrolyzable organic group, but having one or more hydrolyzable groups, with a polyol containing at least three hydroxy groups, where any two of the hydroxy groups are separated by at least three intervening atoms by aerosolization of droplets between 0.5-8 microns are disclosed and an improved formulation comprising adding a nonionic wetting agent are disclosed. An improved aerosolization application technique and the improved formulation provide for smaller droplet size and better coverage of substrates to which the organosilanes are applied. The improved formulation has increased affinity, reduces surface tension and therefore can covalently bond more quickly. A method of treating a substrate, and the treated substrate so formed, by contacting the substrate with the improved formulation for a period of time sufficient for treatment of the substrate are disclosed.