Patents by Inventor Thomas L. Lambert

Thomas L. Lambert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Drug incorporating and releasing polymeric coating for bioprosthesis
    Patent number: 5900246
    Abstract: In accordance with the present invention, there are provided prosthetic articles having polyurethane coatings with biologically active compounds incorporated within the interstices of the polymer. Methods for the preparation of such articles are also provided. Thus, a polyurethane coating is applied to a prosthetic article, the coating then swelled (without significantly dissolving the polymer) so that substantial quantities of biologically active compounds can be incorporated within the interstices of the polymer. Upon long term exposure of a prosthetic article of the invention to physiological conditions, the biologically active compound is slowly released by the treated polymer. The biologically active compound is, therefore, released only at the site where it is desired, i.e., where the prosthetic article is positioned.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: May 4, 1999
    Assignee: Cedars-Sinai Medical Center
    Inventor: Thomas L. Lambert
  • Drug incorporating and release polymeric coating for bioprosthesis
    Patent number: 5562922
    Abstract: In accordance with the present invention, there are provided prosthetic articles having polyurethane coatings with biologically active compounds incorporated within the interstices of the polymer. Methods for the preparation of such articles are also provided. Thus, a polyurethane coating is applied to a prosthetic article, the coating then swelled (without significantly dissolving the polymer) so that substantial quantities of biologically active compounds can be incorporated within the interstices of the polymer. Upon long term exposure of a prosthetic article of the invention to physiological conditions, the biologically active compound is slowly released by the treated polymer. The biologically active compound is, therefore, released only at the site where it is desired, i.e., where the prosthetic article is positioned.
    Type: Grant
    Filed: February 7, 1995
    Date of Patent: October 8, 1996
    Assignee: Cedars-Sinai Medical Center
    Inventor: Thomas L. Lambert