Abstract: A guard assembly for a work machine includes at least one guard including a body. The body in part defines a volume, a first opening, at least one second opening, and at least one pair of first retention tabs. The door defines a first end and a second end. In an open position of the door, the door provides access to the volume and, in a closed position of the door, the door limits access to the volume. The door includes a plate removably coupled to the guard proximal to the first end of the door by at least one fastener, and at least one coupling arrangement extending from the plate for pivotably coupling the plate to the guard proximal to the second end of the door. The coupling arrangement includes a first portion coupled to the plate and a second portion extending from the first portion.

Abstract: The disclosure provides for a system. The system may include a rotational control system configured to rotate a seat of a vehicle, and one or more computing devices. The one or more computing devices may have one or more processors that are configured to determine that an impact is imminent at a location on the vehicle along a collision axis. A most favorable orientation may be determined by the one or more processors based on the determined location and collision axis. Using the rotational control system, the one or more processors may rotate the seat of the vehicle to the most favorable orientation in order to reduce risks of serious injury to a passenger in the seat caused by the imminent impact. A translational control system may be used by the one or more processors to translate the seat of the vehicle to a position relative to the determined location.

Abstract: An apparatus configured to support a diffuser segment during removal from and installation into an assembly. The apparatus includes a body having two or more supports and at least two clamp rods. The clamp rods each extend from a first end to a second end. The body defines a pocket extending between the supports on a first side of the clamp rods. An end clamp releasably mates with the second end of each clamp rod. The end clamp has a foot extending into the first side of the clamp rod. A wheel is received within each support. The pocket and the foot of each end clamp releasably retain a diffuser segment and the wheels rotate to allow the diffuser segment to be removed without damaging a surface coating of the diffuser segment.

Abstract: Antibodies that specifically bind to CD47 and antibodies that specifically bind to PD-L1 are provided, as well as CD47/PD-L1 bispecific antibodies. Also provided are uses of these antibodies, and related compositions and methods.

Abstract: The present disclosure provides, inter alia, compounds with MASP-2 inhibitory activity, compositions of such compounds, and methods of making and using such compounds.

Abstract: In one embodiment, a method of selecting a route for a user is disclosed. The method includes a routing computer presenting a map on a display operably coupled to the routing computer. The routing computer receives a start location and distance criteria via user input, and a plurality of routing criteria. The routing computer determines a plurality of routes that start and end at the start location based on the distance criteria and the routing criteria, and displays at least one of the plurality of routes on the map. Further, the routing computer receives route editing instructions via user input, and modifies at least one of the plurality of routes based on the editing instructions to create one or more modified routes.

Abstract: A support structure for one or more energy storage cells in a power pack, and method of assembling. The support structure may comprise one or more separator walls, a plurality of links, or combinations thereof. The separator walls, links or combinations thereof may be couplable/interlockable to form channels that are configured to receive and at least partially encircle an energy storage cell. Each separator wall may comprise a plurality of troughs that each define a concave surface, and a plurality of ridges, each ridge disposed between adjacent troughs. Each link defines a concave surface and is configured to be releasably coupled/interlocked to another link to form a trough or channel. Each trough is configured to receive and partially encircle an energy storage cell.

Abstract: A battery system for providing standby power to an elevator system is disclosed. The battery system includes a lithium battery cell, a lithium battery module comprising electrically connected cells, a control unit, and a networking unit. The battery system is electrically and communicatively connected to the elevator system and adapted to drive the elevator system when a main power supply is interrupted. Various battery system metrics are reported to the elevator system and, optionally, to a central monitoring station.

Abstract: A power pack module including a power core including a plurality of energy cells, a shell encasing the power core, the shell formed from a pair of interlocking half-shell members, and a weld plate affixed to the shell.

Abstract: A circumaural headset having a first earcup and a second earcup can include a first transducer disposed with the first earcup and configured to transmit a first non-audible signal with an audible signal, a second transducer disposed within the second earcup and configured to receive the first non-audible signal from the first transducer, and an off-ear detection processor configured to determine whether the headset has been removed from the user’s head based on the second transducer receiving the first non-audible signal from the first transducer.

Abstract: The invention relates to the detection of methylmalonic acid (MMA). In a particular aspect, the invention relates to methods for detecting derivatized methylmalonic acid (MMA) by mass spectrometry.

Abstract: The invention relates to the detection of methylmalonic acid (MMA). In a particular aspect, the invention relates to methods for detecting derivatized methylmalonic acid (MMA) by mass spectrometry.

Abstract: The present application discloses compositions and methods utilizing a combination of Pert and ddPCR technologies that yield, for example, the unexpected result of absolute quantification of the presence of RT enzymes. The novel technology disclosed herein is referred to as ddPERT. This is an advance over prior technology such as PERT.

Abstract: The present invention is directed to topical compositions and methods for preventing and treating demodicosis and the symptoms of demodectic mites, including blepharitis, meibomian gland dysfunction, type 1 flushing rosacea, type 2 acne rosacea, type 4 ocular rosacea, demodicosis gravis, granulomatous rosacea, and pityriasis folliculorum, by topical administration of a therapeutically effective amount of piroctone olamine, and in some embodiments, climbazole.

Abstract: A motor vehicle in which a de-coupler has a first attachment point to a cab body, a second attachment point to a vertical engine exhaust pipe, and a de-coupler mechanism having at least one ball joint which allows limited vertical and limited horizontal movement of the engine exhaust pipe relative to the cab body.

Abstract: A machine includes a power source, an engine retarder associated with the power source, and a traction device receiving power from the power source and configured to propel the machine. The machine also includes a brake mechanism associated with the traction device, and a controller in communication with the engine retarder and the brake mechanism. The controller is configured to activate the engine retarder, substantially simultaneously with the brake mechanism, based on a brake pressure associated with the brake mechanism.

Abstract: A machine includes a power source, an engine retarder associated with the power source, and a traction device receiving power from the power source and configured to propel the machine. The machine also includes a brake mechanism associated with the traction device, and a controller in communication with the engine retarder and the brake mechanism. The controller is configured to activate the engine retarder, substantially simultaneously with the brake mechanism, based on a brake pressure associated with the brake mechanism.

Abstract: An apparatus and method for heating a defined space uses an engine to generate the heat required. The heating system includes a tank for heating liquid. A liquid coolant system has conduits which extend between the engine and the tank. A first respective conduit supplies coolant liquid from the tank to the engine and a second respective conduit supplies liquid which has been drawn through the engine and heated to the tank. An exhaust transfer system has an exhaust conduit which extends from the engine to the tank. A heating element is located in the tank to provide a supplemental heat source. Heating conduits extend from the tank to the space to be heated. The liquid coolant system, the exhaust transfer system and the heating element cooperate to heat the liquid in the tank quickly, thereby minimizing run time of the engine and increasing the efficiency of the heating system.

Abstract: A signaling node within a telecommunications network automatically detects that a signaling link is fluctuating in and out of service and provides hysteresis to the fluctuating signaling link. The signaling node includes a link controller that monitors the state(s) of the signaling link over a time period and a link blocking module that blocks the signaling link from carrying SS7 traffic when the signaling link fluctuates between a failed state and a stable state over the time period.

Abstract: A signal transfer point (STP) within a first telecommunications network enables recovery from a linkset failure between the first telecommunications network and a second telecommunications network by deactivating one or more affected signaling routes between the first and second telecommunications networks that include the failed linkset. The STP includes a linkset controller for monitoring the current state of the linkset coupled between the STP and an additional STP within the second telecommunications network. The STP further includes an input interface for receiving a deactivate common channel signaling (CCS) route command from a user when the current state of the linkset indicates failure of the linkset, and a signaling route control module that changes the route status for the affected signaling routes to “prohibited” to prevent SS7 traffic associated with the affected signaling routes from being sent over the linkset.