Abstract: One or more hose clips may advantageously be used to rout and releasably secure a hose assembly such as those included in a vacuum manifold assembly, to a fixed structure of a motor vehicle. The hose clip has a main body which is circumferentially open-sided, partially defining a hose-receiving space which has an inside, free stat cross-sectional dimension and attachment means extending from the main body for attachment into an opening in the firewall of the motor vehicle. The attachment means may preferably be a christmas tree stem. The main body of the hose clip has an opening sized to receive hoses of varying diameters. On one side of the main body of the opening is a flange and on the other side of the main body is a tab. Extending from the flange is a hook with serrations which engage corresponding serrations on the tab to close the opening and retain the hose. The clip may preferably have a pair of hooks, each angled with the flange so as to lockingly secure hoses of different diameters.