Abstract: Provided are methods for assessing T cell receptor ? chain complementary determining region 3 (TCR? CDR3) sequences. In certain embodiments, prior to the assessing, the subject has been identified as having, or is suspected of having, inflammatory bowel disease (IBD). According to some embodiments, at the time of the assessing, the subject has one or more non-specific symptoms consistent with Crohn's disease. Also provided are methods comprising administering a Crohn's disease therapy to a subject identified as comprising T cells that express a T cell receptor ? chain (TCR?) comprising a TCR? CDR3 sequence set forth in the present disclosure. Computer readable media and systems for assessing TCR? CDR3 sequences are also provided.

Abstract: The invention provides methods, devices, compositions and kits for diagnosing or predicting transplant status or outcome in a subject who has received a transplant.

Abstract: The invention provides methods, devices, compositions and kits for diagnosing or predicting transplant status or outcome in a subject who has received a transplant.

Abstract: Disclosed herein are methods for electrolessly coating copper onto a chromium metal powder, the method comprising adding a nickel-coated chromium powder to an aqueous electroless copper plating bath comprising a source of copper cations, a copper-cation complexing agent, a copper-cation reducing agent, and a first base, thereby forming a copper-coated chromium metal powder. Also disclosed are copper-coated chromium metal powders prepared by a disclosed method.

Abstract: Embodiments for assessing flow at an anatomical region of interest are disclosed. One embodiment uses pulsed contrast media injections at a known frequency along with corresponding image data to derive a measurement of blood flow velocity at the region of interest. Another embodiment uses incremental changes in known contrast media injection flow rates to match the blood flow rate relative to one of these known contrast media injection flow rates based on the presence of a particular indicia in image data. For example, this indicia can be the flow of contrast media out from a coronary artery back into the aorta or the onset of a steady state pixel density. A further embodiment uses contrast media injections that are synchronized with the cardiac cycle. For example, contrast media injections can be synchronized with the diastolic and/or systolic phases and used to measure blood flow accordingly.

Abstract: The invention provides methods, devices, compositions and kits for diagnosing or predicting transplant status or outcome in a subject who has received a transplant.

Abstract: The invention provides methods, devices, compositions and kits for diagnosing or predicting transplant status or outcome in a subject who has received a transplant.

Abstract: The invention provides methods, devices, compositions and kits for diagnosing or predicting transplant status or outcome in a subject who has received a transplant.

Abstract: The invention provides methods, devices, compositions and kits for diagnosing or predicting transplant status or outcome in a subject who has received a transplant.

Abstract: An optical device having a first optical member, a second optical member, and an antistatic layer disposed between the first optical member and the second optical member wherein the antistatic layer contains the reaction product of a mixture comprising at least one polymerizable onium salt having an anion and at least one non-onium polymerizable monomer, oligomer, or polymer.

Abstract: The invention provides methods, devices, compositions and kits for diagnosing or predicting transplant status or outcome in a subject who has received a transplant.

Abstract: The invention provides methods, devices, compositions and kits for diagnosing or predicting transplant status or outcome in a subject who has received a transplant.

Abstract: The invention provides methods, devices, compositions and kits for diagnosing or predicting transplant status or outcome in a subject who has received a transplant.

Abstract: The invention provides methods, devices, compositions and kits for diagnosing or predicting transplant status or outcome in a subject who has received a transplant.

Abstract: The invention provides methods, devices, compositions and kits for diagnosing or predicting transplant status or outcome in a subject who has received a transplant.

Abstract: One method for assessing a vessel can include obtaining a set of first location pressure measurements at a first location in the vessel over a first time period and a set of second location pressure measurements at a second location in the vessel over the first time period. This method can further include identifying a first leading characteristic associated with one or more pressure measurements in the set of first location pressure measurements, a second leading characteristic associated with one or more pressure measurements in the set of second location pressure measurements, a first trailing characteristic associated with one or more pressure measurements in the set of first location pressure measurements, and a second trailing characteristic associated with one or more pressure measurements in the set of second location pressure measurements. And, this method can include calculating a pressure ratio using pressure measurements between the identified characteristics.

Abstract: One method for assessing a vessel can include obtaining a set of first location pressure measurements at a first location in the vessel over a first time period and a set of second location pressure measurements at a second location in the vessel over the first time period. This method can further include identifying a first leading characteristic associated with one or more pressure measurements in the set of first location pressure measurements, a second leading characteristic associated with one or more pressure measurements in the set of second location pressure measurements, a first trailing characteristic associated with one or more pressure measurements in the set of first location pressure measurements, and a second trailing characteristic associated with one or more pressure measurements in the set of second location pressure measurements. And, this method can include calculating a pressure ratio using pressure measurements between the identified characteristics.

Abstract: The invention provides methods, devices, compositions and kits for diagnosing or predicting transplant status or outcome in a subject who has received a transplant.

Abstract: The invention provides methods, devices, compositions and kits for diagnosing or predicting transplant status or outcome in a subject who has received a transplant.