Patents by Inventor Thomas Malone

Thomas Malone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7060844
    Abstract: The present invention relates to organic molecules capable of modulating tyrosine kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation.
    Type: Grant
    Filed: April 1, 2003
    Date of Patent: June 13, 2006
    Assignee: Allergan, Inc.
    Inventors: Steven W. Andrews, Xialing Guo, Zhen Zhu, Clarence E. Hull, III, Julie A. Wurster, Shimiao Wang, Edward H. Wang, Thomas Malone
  • Publication number: 20060106112
    Abstract: The present invention provides methods of treating neurological disorders in a mammal by administering to the mammal an effective amount of a selective persistent sodium channel antagonist that has at least 20-fold selectivity for persistent sodium current relative to transient sodium current.
    Type: Application
    Filed: January 5, 2006
    Publication date: May 18, 2006
    Applicant: ALLERGAN, INC.
    Inventors: George Ehring, Joseph Adorante, Larry Wheeler, Thomas Malone, Scott Whitcup
  • Publication number: 20060106103
    Abstract: The present invention provides methods of treating neurological disorders in a mammal by administering to the mammal an effective amount of a selective persistent sodium channel antagonist that has at least 20-fold selectivity for persistent sodium current relative to transient sodium current.
    Type: Application
    Filed: January 5, 2006
    Publication date: May 18, 2006
    Applicant: ALLERGAN, INC.
    Inventors: George Ehring, Joseph Adorante, Larry Wheeler, Thomas Malone, Scott Whitcup
  • Publication number: 20060063940
    Abstract: The present invention relates to organic molecules capable of modulating tyrosine kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation.
    Type: Application
    Filed: November 15, 2005
    Publication date: March 23, 2006
    Inventors: Steven Andrews, Julie Wurster, Edward Wang, Thomas Malone
  • Patent number: 7015220
    Abstract: The present invention relates to organic molecules capable of modulating tyrosine kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation.
    Type: Grant
    Filed: February 20, 2004
    Date of Patent: March 21, 2006
    Assignee: Allergan, Inc.
    Inventors: Steven W. Andrews, Julie A. Wurster, Edward H. Wang, Thomas Malone
  • Publication number: 20060025413
    Abstract: The present invention relates to organic molecules capable of modulating tyrosine kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation.
    Type: Application
    Filed: September 16, 2005
    Publication date: February 2, 2006
    Inventors: Steven Andrews, Julie Wurster, Edward Wang, Thomas Malone
  • Publication number: 20060004084
    Abstract: The present invention relates to organic, molecules capable of modulating tyrosine kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation.
    Type: Application
    Filed: July 12, 2005
    Publication date: January 5, 2006
    Inventors: Steven Andrews, Xialing Guo, Zhen Zhu, Clarence Hull, Julie Wurster, Shimiao Wang, Edward Wang, Thomas Malone
  • Publication number: 20050257222
    Abstract: A method of virtualizing hardware resources in a multiprocessor computing environment is provided. Each resource is provided a resource address. A hardware resource map is provided to store virtual resource addresses and physical resource addresses. Remapping hardware is utilized to redirect virtual addresses to physical addresses. The method of virtualizing hardware resources may be applied to any resource mapped across the bus, including memory address space, and I/O address space. Accordingly, the method of virtualizing hardware resources through platform firmware enables dynamic routing of resource accesses during run-time.
    Type: Application
    Filed: July 22, 2005
    Publication date: November 17, 2005
    Inventors: Brad Davis, Thomas Malone
  • Publication number: 20050244470
    Abstract: Biocompatible intraocular implants include a tyrosine kinase inhibitor and a biodegradable polymer that is effective to facilitate release of the tyrosine kinase inhibitor into an eye for an extended period of time. The therapeutic agents of the implants may be associated with a biodegradable polymer matrix, such as a matrix that is substantially free of a polyvinyl alcohol. The implants may be placed in an eye to treat or reduce the occurrence of one or more ocular conditions.
    Type: Application
    Filed: April 30, 2004
    Publication date: November 3, 2005
    Applicant: Allergan, Inc.
    Inventors: Patrick Hughes, Thomas Malone, Gerald De Vries, Jeffrey Edelman, Joan-En Chang-Lin, Jane Shiah, Thierry Nivaggioli
  • Publication number: 20050244475
    Abstract: Biocompatible intraocular implants include a tyrosine kinase inhibitor and a biodegradable polymer that is effective to facilitate release of the tyrosine kinase inhibitor into the vitreous of an eye for an extended period of time. The therapeutic agents of the implants may be associated with a biodegradable polymer matrix, such as a matrix that is substantially free of a polyvinyl alcohol. The implants can be placed in an eye to treat or reduce the occurrence of one or more ocular conditions, such as posterior ocular conditions.
    Type: Application
    Filed: April 29, 2005
    Publication date: November 3, 2005
    Applicant: ALLERGAN, INC.
    Inventors: Jeffrey Edelman, Patrick Hughes, Thomas Malone, Gerald DeVries, Joan-En Chang-Lin, Jane Shiah, Thierry Nivaggioli, Lon Spada, Wendy Blanda
  • Publication number: 20050232585
    Abstract: A mobile video system comprising a video player having a hinge and a display pivotally attached on the hinge. The video player and the display are contained by a bag which is preferably suspended from and fastened to seats with adjustable straps for viewing by a user, the bag having extensible mesh side panels to facilitate air circulation around the video player and a flap cover that can be opened to access the display. The video player includes a display pivotally attached to a video player that can be flipped up and adjusted to a desired angle for viewing by the user and flipped down when not in use.
    Type: Application
    Filed: May 27, 2005
    Publication date: October 20, 2005
    Inventors: Patrick Lavelle, Thomas Malone, George Schedivy, James Tranchina
  • Publication number: 20050196078
    Abstract: An inflatable insulating panel consisting of a plurality of sheetform polyolefin layers, and its manner of fabrication, is provided. An outer peripheral seal forms an inflatable panel, with an intermediate interconnected web of layers formed out of an array of alternating seams of attachment between the outer and intermediate adjacent layers. Upon inflation of the panel, the interconnected web expands to form a plurality of individual baffle chambers.
    Type: Application
    Filed: May 23, 2005
    Publication date: September 8, 2005
    Applicant: CARGO TECHNOLOGY, INC.
    Inventors: David McKinney, Thomas Malone
  • Publication number: 20050054695
    Abstract: The present invention provides methods of treating neurological disorders in a mammal by administering to the mammal an effective amount of a selective persistent sodium channel antagonist that has at least 20-fold selectivity for persistent sodium current relative to transient sodium current.
    Type: Application
    Filed: August 27, 2004
    Publication date: March 10, 2005
    Inventors: George Ehring, Joseph Adorante, Larry Wheeler, Thomas Malone, Scott Whitcup
  • Publication number: 20050049287
    Abstract: The present invention provides methods of treating chronic pain in a mammal by administering to the mammal an effective amount of a selective persistent sodium channel antagonist that has at least 20-fold selectivity for persistent sodium current relative to transient sodium current.
    Type: Application
    Filed: August 27, 2004
    Publication date: March 3, 2005
    Inventors: George Ehring, Joseph Adorante, John Donello, Larry Wheeler, Thomas Malone
  • Publication number: 20050038076
    Abstract: Synthetic methods for preparing isomerically pure N-arylsulfonyl derivatives of proton pump inhibitors which include a substituted benzimidazole nucleus are shown by the synthetic schemes and experimental description.
    Type: Application
    Filed: July 13, 2004
    Publication date: February 17, 2005
    Inventors: Michael Garst, Lloyd Dolby, Shervin Esfandiari, Vivian MacKenzie, Alfred Avey, David Muchmore, Geoffrey Cooper, Thomas Malone
  • Publication number: 20050034761
    Abstract: A shield for a plug valve is provided to prevent debris from hindering the movement of moving components of the plug valve. The shield prevents larger sized debris from accumulating at an opening in a wall in which the plug valve is mounted, the wall defining a confined space, such as the interior of a vessel, at least in part. The shield encloses but is spaced from the plug valve and a device is located within a space between the shield and the plug valve for directing a purging gas through the space to sweep away or purge smaller sized debris from the space.
    Type: Application
    Filed: August 12, 2004
    Publication date: February 17, 2005
    Inventors: Marius Junier, Thomas Malone
  • Publication number: 20050024356
    Abstract: There is provided a display device for a vehicle having a seat. The display device includes an assembly housing adapted to mount at a rear portion of the seat. A receiver is adapted to receive at least one of video and audio signals from at least one external input device. At least one wireless transmitter operatively coupled to the receiver, is adapted to wirelessly transmit the audio signals to at least one wireless headphone set. The display device is adapted to reproduce the video signals. In some embodiments of the invention, the at least one wireless transmitter is adapted to transmit the audio signals based on Code-Division Multiple Access (CDMA) technology.
    Type: Application
    Filed: August 26, 2004
    Publication date: February 3, 2005
    Inventors: Patrick Lavelle, Thomas Malone, James Tranchina
  • Publication number: 20050020320
    Abstract: There is provided a display device for a vehicle having a seat. The display device includes an assembly housing adapted to mount at a rear portion of the seat. A receiver is adapted to receive at least one of video and audio signals from at least one external input device. At least one wireless transmitter operatively coupled to the receiver, is adapted to wirelessly transmit the audio signals to at least one wireless headphone set. The display device is adapted to reproduce the video signals. In some embodiments of the invention, the at least one wireless transmitter is adapted to transmit the audio signals based on Code-Division Multiple Access (CDMA) technology.
    Type: Application
    Filed: August 5, 2004
    Publication date: January 27, 2005
    Inventors: Patrick Lavelle, Thomas Malone, James Tranchina
  • Publication number: 20040198802
    Abstract: The present invention relates to organic molecules capable of modulating tyrosine kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation.
    Type: Application
    Filed: April 20, 2004
    Publication date: October 7, 2004
    Applicant: Allergan, Inc.
    Inventors: Steven W. Andrews, Michael E. Garst, Xialing Guo, Jonathan J. Hebert, Thomas Malone, Julie A. Wurster, Clarence Eugene Hull
  • Publication number: 20040198720
    Abstract: The present invention relates to organic molecules capable of modulating tyrosine kinase signal transduction in order to regulate, modulate and/or inhibit abnormal cell proliferation.
    Type: Application
    Filed: February 20, 2004
    Publication date: October 7, 2004
    Inventors: Steven W. Andrews, Julie A. Wurster, Edward H. Wang, Thomas Malone