Patents by Inventor Thomas N. Mather

Thomas N. Mather has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for Detection and Prevention of Tick Infestation and Pathogen Transmission
    Publication number: 20100278752
    Abstract: The invention generally features methods for the prevention and detection of a tick infestation. The present invention also features methods for decreasing the ability of a tick to feed on a subject.
    Type: Application
    Filed: July 25, 2008
    Publication date: November 4, 2010
    Applicant: Rhode Island Board of Governors for Higher Education
    Inventors: Michail Kotsyfakis, Jose M.C. Ribeiro, Jesus G. Valenzuela, John F. Andersen, Jennifer M. Anderson, Shahid Karim, Thomas N. Mather
  • Ixodes salivary anticomplement protein
    Patent number: 7153947
    Abstract: Isac, a novel protein with anticomplement activity is disclosed. Isac can be isolated from the salivary glands of ticks or made by recombinant methods using various DNA expression techniques.
    Type: Grant
    Filed: March 28, 2003
    Date of Patent: December 26, 2006
    Assignees: The United States of America as represented by the Department of Health and Human Services, University of Rhode Island
    Inventors: José M. C. Ribeiro, Jesus G. Valenzuela, Rosane Charlab, Thomas N. Mather
  • Ixodes salivary anticomplement protein
    Publication number: 20040019194
    Abstract: Isac, a novel protein with anticomplement activity is disclosed. Isac can be isolated from the salivary glands of ticks or made by recombinant methods using various DNA expression techniques.
    Type: Application
    Filed: March 28, 2003
    Publication date: January 29, 2004
    Inventors: Jose M.C. Ribeiro, Jesus G. Valenzuela, Rosane Charlab, Thomas N. Mather
  • Tick (Ixodes scapularis) vector saliva-induced Lyme disease spirochete (Borrelia burgdorferi) antigens as vaccine candidates
    Patent number: 6312915
    Abstract: The invention relates to a method by which new antigens from vector-borne pathogens may be discovered and analyzed by incubating the viable pathogens in the saliva of their vector host. Three such antigens, proteins with the approximate molecular weights of 19, 22 and 24 kDa, have been discovered and analyzed from a strain of B. burgdorferi T-15. The proteins provide a route for the development of immunodiagnostics for Lyme disease and related disorders. The proteins and related amino acids and DNA sequences may also be used for the immunization, for the detection of B. burgdorfei in human or body fluids, and also for the generation of specific antibodies for use in diagnosis, epidemiology, prevention of and treatment of Lyme disease.
    Type: Grant
    Filed: January 29, 1997
    Date of Patent: November 6, 2001
    Assignees: The Board of Governors for Higher Education, State of Rhode Island, Providence Plantations
    Inventors: David R. Nelson, Thomas N. Mather, Angelo Scorpio
  • Method for the prevention of ectoparasite-mediated pathogen transmission
    Patent number: 5283259
    Abstract: Disclosed is a method for preventing the transmission of an ectoparasite-borne pathogen to a mammal exposed to predation by the ectoparasite, wherein a time delay exists between attachment of the ectoparasite to the mammal and transmission of the pathogen from the ectoparasite to the mammal. The method comprises applying to the mammal an ectoparacide to kill the ectoparasite in place on the mammal, without necessarily finding or mechanically detaching the ectoparasite, at a time after the exposure of the mammal to the ectoparasite, and within the time delay, thereby preventing transmission of the pathogen from the ectoparasite to the mammal.
    Type: Grant
    Filed: September 11, 1992
    Date of Patent: February 1, 1994
    Assignee: The President and Fellows of Harvard College
    Inventor: Thomas N. Mather
  • Method and apparatus for administering acaricides and insecticides to ectoparasites of rodents
    Patent number: 4662104
    Abstract: Insecticide is administered to ectoparasites of rodents by filling a container with insecticide-impregnated fibrous nesting material and fixing it in a desired location. The container has an aperture permitting entry by rodents. Rodents incorporate the insecticide-impregnated fibrous material into their nests, thus exposing ectoparasites and their nymphs and larvae attached to these hosts, as well as those otherwise dwelling in the rodent's nest, to the insecticide.
    Type: Grant
    Filed: October 25, 1985
    Date of Patent: May 5, 1987
    Inventors: Thomas N. Mather, Jose-Marcos C. Ribeiro, Andrew Spielman