Patents by Inventor Thomas Neils
Thomas Neils has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9601032Abstract: Devices, systems, and methods appropriate for use in medical training that include materials that better mimic natural human tissue are disclosed. In one aspect a polysiloxane mixture for simulating human biological tissue, especially human breast tissue, is disclosed. In another aspect, a method of manufacturing a biological tissue ultrasound phantom is disclosed. In another aspect, a human breast tissue models are disclosed. In some instances, the human breast tissue model includes at least one simulated pathological structure that simulates such pathologies as a cyst, a medullary carcinoma, a ductal carcinoma, an infiltrating scirrhus carcinoma, a lobular carcinoma, and a fibroadenoma.Type: GrantFiled: February 26, 2016Date of Patent: March 21, 2017Assignee: Gaumard Scientific Company, Inc.Inventors: Thomas Neil Trotta, Jennifer Anne Trotta, Siobhain Lowe
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Publication number: 20170069231Abstract: Devices, systems, and methods appropriate for use in medical training that include materials that better mimic natural human tissue are disclosed. In one aspect, multi-layer tissue simulations are provided. In another aspect, male genitalia models are provided. In another aspect, abdominal surgical wall inserts are provided. Systems and methods associated with these devices are also provided.Type: ApplicationFiled: October 17, 2016Publication date: March 9, 2017Applicant: Gaumard Scientific Company, Inc.Inventors: Thomas Neil Trotta, Jennifer Anne Trotta, Siobhain Lowe
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Patent number: 9472123Abstract: Devices, systems, and methods appropriate for use in medical training that include materials that better mimic natural human tissue are disclosed. In one aspect, methods of forming multi-layer tissue simulations are provided. In another aspect, methods of forming a male genitalia model are provided. In another aspects, methods of forming an abdominal surgical wall insert are provided. Devices and systems associated with these methods are also provided.Type: GrantFiled: January 25, 2013Date of Patent: October 18, 2016Assignee: Gaumard Scientific Company, Inc.Inventors: Thomas Neil Trotta, Jennifer Anne Trotta, Siobhain Lowe
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Patent number: 9434707Abstract: Compounds that inhibit PDE10 are disclosed that have utility in the treatment of a variety of conditions, including (but not limited to) psychotic, anxiety, movement disorders and/or neurological disorders such as Parkinson's disease, Huntington's disease, Alzheimer's disease, encephalitis, phobias, epilepsy, aphasia, Bell's palsy, cerebral palsy, sleep disorders, pain, Tourette's syndrome, schizophrenia, delusional disorders, drug-induced psychosis and panic and obsessive-compulsive disorders. Pharmaceutically acceptable salts, stereoisomers, solvates and prodrugs of the compounds are also provided. Also disclosed are compositions containing a compound in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for inhibiting PDE10 in a warm-blooded animal in need of the same.Type: GrantFiled: January 20, 2015Date of Patent: September 6, 2016Assignee: OMEROS CORPORATIONInventors: Neil S. Cutshall, Jennifer Lynn Gage, Thomas Neil Wheeler, Thomas L. Little
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Publication number: 20160180745Abstract: Devices, systems, and methods appropriate for use in medical training that include materials that better mimic natural human tissue are disclosed. In one aspect a polysiloxane mixture for simulating human biological tissue, especially human breast tissue, is disclosed. In another aspect, a method of manufacturing a biological tissue ultrasound phantom is disclosed. In another aspect, a human breast tissue models are disclosed. In some instances, the human breast tissue model includes at least one simulated pathological structure that simulates such pathologies as a cyst, a medullary carcinoma, a ductal carcinoma, an infiltrating scirrhus carcinoma, a lobular carcinoma, and a fibroadenoma.Type: ApplicationFiled: February 26, 2016Publication date: June 23, 2016Inventors: Thomas Neil Trotta, Jennifer Anne Trotta, Siobhain Lowe
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Patent number: 9275557Abstract: Devices, systems, and methods appropriate for use in medical training that include materials that better mimic natural human tissue are disclosed. In one aspect a polysiloxane mixture for simulating human biological tissue, especially human breast tissue, is disclosed. In another aspect, a method of manufacturing a biological tissue ultrasound phantom is disclosed. In another aspect, a human breast tissue models are disclosed. In some instances, the human breast tissue model includes at least one simulated pathological structure that simulates such pathologies as a cyst, a medullary carcinoma, a ductal carcinoma, an infiltrating scirrhus carcinoma, a lobular carcinoma, and a fibroadenoma.Type: GrantFiled: March 24, 2014Date of Patent: March 1, 2016Assignee: Gaumard Scientific Company, Inc.Inventors: Thomas Neil Trotta, Jennifer Anne Trotta, Siobhain Lowe
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Patent number: 9102643Abstract: Compounds that inhibit PDE10 are disclosed that have utility in the treatment of a variety of conditions, including (but not limited to) psychotic, anxiety, movement disorders and/or neurological disorders such as Parkinson's disease, Huntington's disease, Alzheimer's disease, encephalitis, phobias, epilepsy, aphasia, Bell's palsy, cerebral palsy, sleep disorders, pain, Tourette's syndrome, schizophrenia, delusional disorders, drug-induced psychosis and panic and obsessive-compulsive disorders. Pharmaceutically acceptable salts, stereoisomers, solvates and prodrugs of the compounds are also provided. Also disclosed are compositions containing a compound in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for inhibiting PDE10 in a warm-blooded animal in need of the same.Type: GrantFiled: February 11, 2014Date of Patent: August 11, 2015Assignee: OMEROS CORPORATIONInventors: Neil S. Cutshall, Jennifer Lynn Gage, Thomas Neil Wheeler, Thomas L. Little
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Publication number: 20150133675Abstract: Compounds that inhibit PDE10 are disclosed that have utility in the treatment of a variety of conditions, including (but not limited to) psychotic, anxiety, movement disorders and/or neurological disorders such as Parkinson's disease, Huntington's disease, Alzheimer's disease, encephalitis, phobias, epilepsy, aphasia, Bell's palsy, cerebral palsy, sleep disorders, pain, Tourette's syndrome, schizophrenia, delusional disorders, drug-induced psychosis and panic and obsessive-compulsive disorders. Pharmaceutically acceptable salts, stereoisomers, solvates and prodrugs of the compounds are also provided. Also disclosed are compositions containing a compound in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for inhibiting PDE10 in a warm-blooded animal in need of the same.Type: ApplicationFiled: January 20, 2015Publication date: May 14, 2015Inventors: Neil S. Cutshall, Jennifer Lynn Gage, Thomas Neil Wheeler, Thomas L. Little
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Patent number: 8974496Abstract: Devices, tools and methods for minimally invasive implantation and distraction between spinous processes for treatment of spinous disorders. An interspinous implant device for distracting at least one pair of adjacent spinous processes includes a main body including a shaft having a longitudinal axis; and first and second arms extending transversely from the main body, wherein at least one of the first and second arms is slidably mounted with respect to the shaft. The arms are configured and dimensioned to extend laterally from both sides of the spinous processes when implanted therebetween and to be inserted between the spinous processes laterally from a single side thereof. The arms are variably positionable between a closed configuration, to facilitate insertion of the arms between the adjacent spinous processes, and an open configuration, in which the arms are separated from one another.Type: GrantFiled: August 30, 2007Date of Patent: March 10, 2015Inventors: Jeffrey Chun Wang, Thomas Neil Scioscia, Adrian Slattery, Alan W. Cannon
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Publication number: 20140308643Abstract: Devices, systems, and methods appropriate for use in medical training that include materials that better mimic natural human tissue are disclosed. In one aspect a polysiloxane mixture for simulating human biological tissue, especially human breast tissue, is disclosed. In another aspect, a method of manufacturing a biological tissue ultrasound phantom is disclosed. In another aspect, a human breast tissue models are disclosed. In some instances, the human breast tissue model includes at least one simulated pathological structure that simulates such pathologies as a cyst, a medullary carcinoma, a ductal carcinoma, an infiltrating scirrhus carcinoma, a lobular carcinoma, and a fibroadenoma.Type: ApplicationFiled: March 24, 2014Publication date: October 16, 2014Applicant: Gaumard Scientific Company, Inc.Inventors: Thomas Neil Trotta, Jennifer Anne Trotta, Siobhain Lowe
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Publication number: 20140228581Abstract: Compounds that inhibit PDE10 are disclosed that have utility in the treatment of a variety of conditions, including (but not limited to) psychotic, anxiety, movement disorders and/or neurological disorders such as Parkinson's disease, Huntington's disease, Alzheimer's disease, encephalitis, phobias, epilepsy, aphasia, Bell's palsy, cerebral palsy, sleep disorders, pain, Tourette's syndrome, schizophrenia, delusional disorders, drug-induced psychosis and panic and obsessive-compulsive disorders. Pharmaceutically acceptable salts, stereoisomers, solvates and prodrugs of the compounds are also provided. Also disclosed are compositions containing a compound in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for inhibiting PDE10 in a warm-blooded animal in need of the same.Type: ApplicationFiled: February 11, 2014Publication date: August 14, 2014Applicant: Omeros CorporationInventors: Neil S. Cutshall, Jennifer Lynn Gage, Thomas Neil Wheeler, Thomas L. Little
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Patent number: 8721688Abstract: One exemplary device includes a main body including a shaft having a longitudinal axis; a first clamping mechanism having first and second jaws configured to clamp a spinous process of a first vertebra, and a second clamping mechanism having third and fourth jaws configured to clamp a spinous process of a second vertebra. The first, second, third and fourth jaws extend transversely from the shaft and at least two of two of the jaws are releasably mounted to the shaft and are mountable to and removable from the shaft by relative movement between the respective jaw and the shaft in a direction normal to a longitudinal axis of the shaft.Type: GrantFiled: May 18, 2012Date of Patent: May 13, 2014Assignee: Collabcom II, LLCInventors: Jeffrey Chun Wang, Thomas Neil Scioscia, Adrian Slattery, Alan W. Cannon
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Patent number: 8685975Abstract: Compounds that inhibit PDE10 are disclosed that have utility in the treatment of a variety of conditions, including (but not limited to) psychotic, anxiety, movement disorders and/or neurological disorders such as Parkinson's disease, Huntington's disease, Alzheimer's disease, encephalitis, phobias, epilepsy, aphasia, Bell's palsy, cerebral palsy, sleep disorders, pain, Tourette's syndrome, schizophrenia, delusional disorders, drug-induced psychosis and panic and obsessive-compulsive disorders. Pharmaceutically acceptable salts, stereoisomers, solvates and prodrugs of the compounds are also provided. Also disclosed are compositions containing a compound in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for inhibiting PDE10 in a warm-blooded animal in need of the same.Type: GrantFiled: November 16, 2012Date of Patent: April 1, 2014Assignee: Omeros CorporationInventors: Neil S. Cutshall, Jennifer Lynn Gage, Thomas Neil Wheeler, Thomas L. Little
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Patent number: 8678831Abstract: Devices, systems, and methods appropriate for use in medical training that include materials that better mimic natural human tissue are disclosed. In one aspect a polysiloxane mixture for simulating human biological tissue, especially human breast tissue, is disclosed. In another aspect, a method of manufacturing a biological tissue ultrasound phantom is disclosed. In another aspect, a human breast tissue models are disclosed. In some instances, the human breast tissue model includes at least one simulated pathological structure that simulates such pathologies as a cyst, a medullary carcinoma, a ductal carcinoma, an infiltrating scirrhus carcinoma, a lobular carcinoma, and a fibroadenoma.Type: GrantFiled: February 18, 2011Date of Patent: March 25, 2014Assignee: Gaumard Scientific Company, Inc.Inventors: Thomas Neil Trotta, Jennifer Anne Trotta, Siobhain Lowe
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Publication number: 20140051052Abstract: A patient simulator system for teaching patient care is provided. The system includes a patient simulator. The patient simulator includes a patient body comprising one or more simulated body portions. The one or more simulated body portions include a lung compliance simulation system in some instances. In that regard, the lung compliance system is configured to be used with an external ventilator, including positive end-expiratory pressure (PEEP) and assisted-control ventilation. In some instances, the lung compliance system includes a lung compartment, a simulated lung positioned within the lung compartment, where the lung compartment defines an available volume for the simulated lung to expand into and where the available volume for the simulated lung to expand into is adjustable to control a compliance of the simulated lung.Type: ApplicationFiled: August 26, 2013Publication date: February 20, 2014Applicant: Gaumard Scientific Company, Inc.Inventors: Thomas Neil Trotta, Siobhain Lowe, Alberto Rodriguez, Miguel Carvajal, Victor I. Fernandez
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Publication number: 20140038951Abstract: Compounds that inhibit PDE10 are disclosed that have utility in the treatment of a variety of conditions, including (but not limited to) psychotic, anxiety, movement disorders and/or neurological disorders such as Parkinson's disease, Huntington's disease, Alzheimer's disease, encephalitis, phobias, epilepsy, aphasia, Bell's palsy, cerebral palsy, sleep disorders, pain, Tourette's syndrome, schizophrenia, delusional disorders, drug-induced psychosis and panic and obsessive-compulsive disorders. Pharmaceutically acceptable salts, stereoisomers, solvates and prodrugs of the compounds are also provided. Also disclosed are compositions containing a compound in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for inhibiting PDE10 in a warm-blooded animal in need of the same.Type: ApplicationFiled: January 15, 2013Publication date: February 6, 2014Applicant: OMEROS CORPORATIONInventors: Neil S. Cutshall, Jennifer Lynn Gage, Thomas Neil Wheeler
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Patent number: 8608483Abstract: Devices, systems, and methods appropriate for use in medical training that include materials that better mimic natural human tissue are disclosed. In one aspect a polysiloxane mixture for simulating human biological tissue, especially human breast tissue, is disclosed. In another aspect, a method of manufacturing a biological tissue phantom is disclosed. In another aspect, a human breast tissue models are disclosed. In one instances, the human breast tissue model comprises a simulated breast tissue comprising a mixture of a silicone foam and a silicone oil and a simulated skin layer covering the simulated breast tissue, where the simulated breast tissue and the simulated skin layer are sized and shaped to mimic a natural human breast. In some instances, the human breast tissue model includes at least one simulated pathological structure that simulates such pathologies as a cyst, a medullary carcinoma, a ductal carcinoma, an infiltrating scirrhus carcinoma, a lobular carcinoma, and a fibroadenoma.Type: GrantFiled: February 18, 2011Date of Patent: December 17, 2013Assignee: Gaumard Scientific Company, Inc.Inventors: Thomas Neil Trotta, Jennifer Anne Trotta, Siobhain Lowe
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Patent number: 8517740Abstract: A patient simulator system for teaching patient care is provided. The system includes a patient simulator. The patient simulator includes a patient body comprising one or more simulated body portions. The one or more simulated body portions include a lung compliance simulation system in some instances. In that regard, the lung compliance system is configured to be used with an external ventilator, including positive end-expiratory pressure (PEEP) and assisted-control ventilation. In some instances, the lung compliance system includes a lung compartment, a simulated lung positioned within the lung compartment, where the lung compartment defines an available volume for the simulated lung to expand into and where the available volume for the simulated lung to expand into is adjustable to control a compliance of the simulated lung.Type: GrantFiled: February 18, 2011Date of Patent: August 27, 2013Assignee: Gaumard Scientific Company, Inc.Inventors: Thomas Neil Trotta, Siobhain Lowe, Alberto Rodriguez, Miguel Enrique Carvajal, Victor I. Fernandez
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Patent number: 8500452Abstract: A patient simulator system for teaching patient care is provided. The system includes a patient simulator. The patient simulator includes a patient body comprising one or more simulated body portions. The one or more simulated body portions include at least one simulated finger that is configured to interface with a pulse oximeter to simulate an oxygen saturation of the patient simulator. In some instances, the simulated finger is further configured to interface with the pulse oximeter to simulate a pulse rate of the patient simulator. In some embodiments, the simulated finger may be calibrated to accurately interface with a particular pulse oximeter. Methods of utilizing the patient simulator systems, including the simulated finger for interfacing with a pulse oximeter, are also provided.Type: GrantFiled: February 19, 2010Date of Patent: August 6, 2013Assignee: Gaumard Scientific Company, Inc.Inventors: Thomas Neil Trotta, Siobhain Lowe, Alberto Rodriguez, Miguel Enrique Carvajal, Victor I. Fernandez
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Patent number: D700245Type: GrantFiled: May 14, 2012Date of Patent: February 25, 2014Inventor: Thomas Neil Overbay