Patents by Inventor Thomas O Metz

Thomas O Metz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180200312
    Abstract: The present invention provides for a probiotic composition designed to enhance memory and/or reduce fear and/or pain of a host, the probiotic composition comprising viable or live cells of one or more of the family/order/strain selected from a group consisting of RF39, Lactobacillaceae, Bacteroidaceae, Lachnospiraceae, Anaeroplasmataceae, Ruminococcaceae, Clostridiales, Clostridiaceae, Rikenellaceae, Erysipelotrichaceae, Peptococcaceae, Turicibacteraceae, Deferribacteraceae, Cytophagaceae, Chitinophagaceae, Coriobacteriaceae, Bifidobacteriaceae, and S24.7. The present invention also provides for a method of enhancing memory and/or reducing fear and/or pain of a host, the method comprising: administering the probiotic composition to a host.
    Type: Application
    Filed: January 17, 2018
    Publication date: July 19, 2018
    Applicants: The Regents of the University of California, Battelle Memorial Institute
    Inventors: Antoine M. Snijders, Jian-Hua Mao, Sasha A. Langley, Thomas O. Metz, Janet K. Jansson
  • Patent number: 9429569
    Abstract: A method for identifying persons with increased risk of developing type 1 diabetes mellitus, or having type I diabetes mellitus, utilizing selected biomarkers described herein either alone or in combination. The present disclosure allows for broad based, reliable, screening of large population bases. Also provided are arrays and kits that can be used to perform such methods.
    Type: Grant
    Filed: May 2, 2014
    Date of Patent: August 30, 2016
    Assignee: Battelle Memorial Institute
    Inventors: Qibin Zhang, Thomas O. Metz
  • Publication number: 20140274792
    Abstract: A method for identifying persons with increased risk of developing type 1 diabetes mellitus, or having type I diabetes mellitus, utilizing selected biomarkers described herein either alone or in combination. The present disclosure allows for broad based, reliable, screening of large population bases. Also provided are arrays and kits that can be used to perform such methods.
    Type: Application
    Filed: May 2, 2014
    Publication date: September 18, 2014
    Applicant: Battelle Memorial Institute
    Inventors: Qibin Zhang, Thomas O. Metz
  • Patent number: 8748352
    Abstract: A method for identifying persons with increased risk of developing type 1 diabetes mellitus, or having type I diabetes mellitus, utilizing selected biomarkers described herein either alone or in combination. The present disclosure allows for broad based, reliable, screening of large population bases. Also provided are arrays and kits that can be used to perform such methods.
    Type: Grant
    Filed: August 15, 2012
    Date of Patent: June 10, 2014
    Assignee: Battelle Memorial Institute
    Inventors: Qibin Zhang, Thomas O. Metz
  • Patent number: 8673644
    Abstract: A method for identifying persons with increased risk of developing type 2 diabetes mellitus utilizing selected biomarkers described hereafter either alone or in combination. The present invention allows for broad based, reliable, screening of large population bases and provides other advantages, including the formulation of effective strategies for characterizing, archiving, and contrasting data from multiple sample types under varying conditions.
    Type: Grant
    Filed: May 13, 2008
    Date of Patent: March 18, 2014
    Assignee: Battelle Memorial Institute
    Inventors: Thomas O. Metz, Wei-Jun Qian, Jon M. Jacobs, Ashoka D. Polpitiya, David G. Camp, II, Richard D. Smith
  • Publication number: 20130045887
    Abstract: A method for identifying persons with increased risk of developing type 1 diabetes mellitus, or having type I diabetes mellitus, utilizing selected biomarkers described herein either alone or in combination. The present disclosure allows for broad based, reliable, screening of large population bases. Also provided are arrays and kits that can be used to perform such methods.
    Type: Application
    Filed: August 15, 2012
    Publication date: February 21, 2013
    Inventors: Qibin Zhang, Thomas O. Metz
  • Patent number: 7923253
    Abstract: A method and system for classifying subject populations utilizing predictive and diagnostic biomarkers for type I diabetes mellitus. The method including determining the levels of a variety of markers within the serum or plasma of a target organism and correlating this level to general populations as a screen for predisposition or progressive monitoring of disease presence or predisposition.
    Type: Grant
    Filed: November 5, 2008
    Date of Patent: April 12, 2011
    Assignee: Battelle Memorial Institute
    Inventors: Thomas O Metz, Weijun Qian, Jon M. Jacobs, David G. Camp, II, Richard D. Smith
  • Publication number: 20090286324
    Abstract: A method for identifying persons with increased risk of developing type 2 diabetes mellitus utilizing selected biomarkers described hereafter either alone or in combination. The present invention allows for broad based, reliable, screening of large population bases and provides other advantages, including the formulation of effective strategies for characterizing, archiving, and contrasting data from multiple sample types under varying conditions.
    Type: Application
    Filed: May 13, 2008
    Publication date: November 19, 2009
    Inventors: Thomas O. Metz, Wei-Jun Qian, Jon M. Jacobs, Ashoka D. Polpitiya, David G. Camp, II, Richard D. Smith
  • Publication number: 20090117578
    Abstract: A method and system for classifying subject populations utilizing predictive and diagnostic biomarkers for type I diabetes mellitus. The method including determining the levels of a variety of markers within the serum or plasma of a target organism and correlating this level to general populations as a screen for predisposition or progressive monitoring of disease presence or predisposition.
    Type: Application
    Filed: November 5, 2008
    Publication date: May 7, 2009
    Inventors: Thomas O. Metz, Weijun Qian, Jon M. Jacobs, David G. Camp, II, Richard D. Smith