Abstract: A device to orient a riser of a parachute. The device can include a twist body that is includes a slot through which the riser passes. The slot includes a twist to change the orientation of the riser from a relatively high-profile orientation to a relatively low-profile orientation. The device can also include a link to connect the riser to the suspension lines on the canopy.

Abstract: Systems and methods are disclosed for monitoring adherence to healthcare guidelines defining a recommended level of physical activity. Metabolic Equivalent (MET) data for a user over a plurality of days is analysed to determine whether sufficient MET data is available, by determining whether the obtained MET data includes at least a minimum amount of MET data within a defined time period. In response to a determination that sufficient MET data is available, the MET data is compared to guideline MET values relating to the recommended level of physical activity, to determine whether the user has achieved the recommended level of physical activity. An adherence result is outputted in accordance with the result of the comparison, indicating whether the user has achieved the recommended level of physical activity. The adherence result can be outputted in the form of a message displayed on a display unit.

Abstract: A device to orient a riser of a parachute. The device can include a twist body that is includes a slot through which the riser passes. The slot includes a twist to change the orientation of the riser from a relatively high-profile orientation to a relatively low-profile orientation. The device can also include a link to connect the riser to the suspension lines on the canopy.

Abstract: A flying toy system capable of independently hovering at a programmable height and respond to the manipulations and/or actions of one or more users through their fingers or similar digit extensions, all while continuing an autonomous flight regime.

Abstract: An apparatus includes a platform having a first end and a second end and a handle. The apparatus includes a first leg assembly rotatably attached to the platform in proximity to the first end. The apparatus includes a second leg assembly attentively attached to the platform in proximity to the second end. When the first and second leg assemblies are essentially perpendicular to the platform, the apparatus is in a use state and the user is able to stand on the platform and be supported by the first and second leg assemblies. When the apparatus is in the use state, the user is able to pick up the apparatus by the handle with only one of the hands without tipping the apparatus. A method for a user with hands to stand on an apparatus. A work platform having legs which are coplanar with the platform when the legs are in a closed position. The work platform having a hinge bracket with a tab against which a leg contacts and is stopped when the leg is in an open position.

Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; Wherein R1, R3-R6, X2 and X3 are as defined herein, a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Abstract: Methods and compositions for controlling parasitic nematodes and treating or preventing a parasitic nematode infection are described herein. The methods include the use of compositions containing an autophagy inhibitor and/or a DCAR-1 inhibitor as anthelmintic agents.

Abstract: A device to orient a riser of a parachute. The device can include a twist body that is includes a slot through which the riser passes. The slot includes a twist to change the orientation of the riser from a relatively high-profile orientation to a relatively low-profile orientation. The device can also include a link to connect the riser to the suspension lines on the canopy.

Abstract: A device to orient a riser of a parachute. The device can include a twist body that is includes a slot through which the riser passes. The slot includes a twist to change the orientation of the riser from a relatively high-profile orientation to a relatively low-profile orientation. The device can also include a link to connect the riser to the suspension lines on the canopy.

Abstract: Engineered antibody compounds and conjugates thereof, are provided, said antibody compounds and conjugates thereof are useful as agents for cancer immunotherapy.

Abstract: A ceiling ladder having a plurality of sections that can be climbed by a user when in an unfolded position into an attic and that can be folded together into a retracted position to be stored above the ceiling. The ladder has a deep step, which has a width greater than the width of other steps of the ladder, in which is located between about 2-5 feet from the floor when the ladder is in the unfolded position so user can stand on the deep step in place objects into the attic without having to climb into the attic. A method. A deep step.

Abstract: A ceiling ladder having a plurality of sections that can be climbed by a user when in an unfolded position into an attic and that can be folded together into a retracted position to be stored above the ceiling. The ladder has a deep step, which has a width greater than the width of other steps of the ladder, in which is located between about 2-5 feet from the floor when the ladder is in the unfolded position so user can stand on the deep step in place objects into the attic without having to climb into the attic. A method. A deep step.

Abstract: The invention relates to a device, system and method for registering a hit on a target and in particular to an improved device, system and method for registering the hit quickly to reduce feedback delay time.

Abstract: A multipurpose ladder having a first inner section. The ladder has a first articulated hinge and a second articulated hinge. The ladder has a second inner section. The ladder has a first outer section. The ladder has a first locking bar. The ladder has a second outer section. The multipurpose ladder may have a plurality of brackets disposed about outer rails of the outer sections. The brackets provide support to each of the outer rails and strengthens them against bending forces so the rails can be thinner and of lighter weight. The ladder may have an ANSI duty rating of 1A or an ANSI duty rating of 1AA. A method for using a multipurpose ladder. A method for producing a multipurpose ladder.

Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; Wherein R1, R3-R6, X2 and X3 are as defined herein, a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; Wherein R1, R3-R6, X2 and X3 are as defined herein, a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Abstract: A ceiling ladder having a plurality of sections that can be climbed by a user when in an unfolded position into an attic and that can be folded together into a retracted position to be stored above the ceiling. The ladder has a deep step, which has a width greater than the width of other steps of the ladder, in which is located between about 2-5 feet from the floor when the ladder is in the unfolded position so user can stand on the deep step in place objects into the attic without having to climb into the attic. A method. A deep step.

Abstract: An apparatus includes a platform having a first end and a second end and a handle. The apparatus includes a first leg assembly rotatably attached to the platform in proximity to the first end. The apparatus includes a second leg assembly attentively attached to the platform in proximity to the second end. When the first and second leg assemblies are essentially perpendicular to the platform, the apparatus is in a use state and the user is able to stand on the platform and be supported by the first and second leg assemblies. When the apparatus is in the use state, the user is able to pick up the apparatus by the handle with only one of the hands without tipping the apparatus. A method for a user with hands to stand on an apparatus. A work platform having legs which are coplanar with the platform when the legs are in a closed position. The work platform having a hinge bracket with a tab against which a leg contacts and is stopped when the leg is in an open position.