Abstract: Head-mounted display systems with power saving functionality are disclosed. The systems can include a frame configured to be supported on the head of the user. The systems can also include a head-mounted display disposed on the frame, one or more sensors, and processing electronics in communication with the display and the one or more sensors. In some implementations, the processing electronics can be configured to cause the system to reduce power of one or more components in response to at least in part on a determination that the frame is in a certain position (e.g., upside-down or on top of the head of the user). In some implementations, the processing electronics can be configured to cause the system to reduce power of one or more components in response to at least in part on a determination that the frame has been stationary for at least a threshold period of time.

Abstract: A catheter assembly comprises a catheter having an axial lumen that houses electrical wires. A plurality of splines, each supporting at least one electrode, are connected to the wires and a distal cap. The splines have a basket shape in a deployed position and a collapsed shape when received inside the catheter axial lumen. A flexible tube extending outwardly from the catheter lumen has a tube lumen of a first, inner diameter and a distal tube end that is spaced proximally from the distal cap. A guide shaft extending proximally from the distal cap has a second, outer diameter that is less than the first diameter of the tube lumen. With the guide shaft received in the tube lumen, an annulus is formed by the tube lumen surrounding the guide shaft. With the splines in the deployed position, the annulus permits flushing of the area adjacent to the deployed splines.

Abstract: Provided herein are bispecific antigen-binding molecules that bind HER2 and methods of use thereof. The bispecific antigen-binding molecules comprise a first and a second antigen-binding domain, wherein the first and second antigen-binding domains bind to two different (preferably non-overlapping) epitopes of the extracellular domain of human HER2. The bispecific antigen-binding molecules cluster on the surface of HER2 IHC2+ and IHC3+ cells, and are internalized into the cellular lysosomes. Also included are antibody-drug conjugates (ADCs) comprising the antibodies or bispecific antigen-binding molecules provided herein linked to a cytotoxic agent, radionuclide, or other moiety, as well as methods of treating cancer in a subject by administering to the subject a bispecific antigen-binding molecule or an ADC thereof.

Abstract: The present invention relates to a preferably computer-implemented method of raising a group of monogastric animals Issues such as exposure of the animals to an initiator of a disease are recognized at an early stage by ex vivo analysis of blood samples. Said analysis is done where the animals are raised using point-of-care devices. Accuracy of separation between affected and non-affected animals is increased by measuring a set of pre-determined blood parameters. The landless monogastric animal production system of the invention facilitates implementation of the method of the invention.

Abstract: Various techniques facilitate the development of an image library that can be used to train and/or validate an automated visual inspection (AVI) model, such an AVI neural network for image classification. In one aspect, an arithmetic transposition algorithm is used to generate synthetic images from original images by transposing features (e.g., defects) onto the original images, with pixel-level realism. In other aspects, digital inpainting techniques are used to generate realistic synthetic images from original images. Deep learning-based inpainting techniques may be used to add, remove, and/or modify defects or other depicted features. In still other aspects, quality control techniques are used to assess the suitability of image libraries for training and/or validation of AVI models, and/or to assess whether individual images are suitable for inclusion in such libraries.

Abstract: A vehicle interior panel having a substrate, a foam layer, and a decorative layer, particularly for a vehicle armrest. The panel includes a foam pad having an inner side, an outer side, and a foam pin located on the outer side. The panel has a substrate having an inner side, an outer side, and an integrated clip. The integrated clip defines an insertion aperture and a flex aperture. The insertion aperture houses the foam pin such that the outer side of the foam pad is held against the inner side of the substrate.

Abstract: A sublingual, ultra violet (UV) light device is disclosed. The light device is comprised of a cold cathode ray tube and a light emitting diode (LED) and a mouth piece. Embodiments of the device can include an onboard controller, a handle and can be powered by a multitude of sources. The light device combines light from a cold cathode ray tube with light from LEDs to enhance the various wavelength exposures to the user. An object of the invention is to enhance conventional cold cathode ray tube immunotherapy with complementary LED light.

Abstract: A finger mounted toothbrush system includes a sheath constructed of a flexible, textured substrate; a rigid, pronged skeleton that fits into the substrate; and a retaining ring that secures the sheath to the skeleton. Prongs of skeleton may be constructed of thermoplastic that can be hardened to fit a user's finger size.

Abstract: A finger mounted toothbrush system includes a sheath constructed of a flexible, textured substrate; a rigid, pronged skeleton that fits into the substrate; and a retaining ring that secures the sheath to the skeleton. Prongs of skeleton may be constructed of thermoplastic that can be hardened to fit a user's finger size.

Abstract: Embodiments of an apparatus for draining liquid generally include a liquid inlet, a p-trap, an additive reservoir, a fluid outlet, a float switch, a valve, and a fitting, wherein the liquid inlet allows for introduction of liquid, the p-trap allows for maintenance of a liquid level whereby contact is provided between the liquid and an additive contained in the additive reservoir, the fluid outlet is configured to maintain the liquid level above an additive reservoir bottom interior surface, the float switch provides indication of high liquid level, the valve allows for blockage of fluid flow between the p-trap and the liquid inlet, and the fitting allows for introduction of high-pressure fluid into the apparatus. Embodiments of a method for clearing a liquid draining apparatus generally include ceasing flow of liquid there into, operating a valve to substantially prevent reverse flow of liquid therefrom, and providing high-pressure fluid into the apparatus.

Abstract: In one embodiment there is provided a system for light therapy. The system includes a light guide transmission device having at least one UV bulb for dispersing UV light a light guide cable to a light guide terminating end, an optical capturing device operable to receive an image from a lens positioned at an optical cable terminating end, and a fluid delivery/suction device along a flexible hose. Each of the cables being inserted into a probe cable having a tip adapted for use internally or externally with a patient. Further the system includes a single controller in communication with and for controlling the functionality of the light guide transmission device, the optical capturing device, and the fluid delivery/suction device.

Abstract: The present invention is directed to a skin cream containing L-glutathione and methyl sulfone in combination with perfluorodecalin and various vitamins such as Vitamin D and C. The cream can be used to treat cancerous and precancerous diseases found in or on the skin.

Abstract: In one embodiment there is provided a spinal needle having a cannula defining an interior hollowed region with a longitudinal length and opposite proximal and distal ends. The cannula includes an opening at its distal end. The spinal needle further includes a UV light source and a light transmission tube positioned within the cannula for transmitting UV light emitting from the UV light source. The light transmission tube having a length extending through the longitudinal length of the cannula and having a distal end positioned at or about the distal end of the cannula.

Abstract: The present invention is directed to a skin cream containing L-glutathione and methyl sulfone in combination with perfluorodecalin and various vitamins such as Vitamin D and C. The cream can be used to treat cancerous and precancerous diseases found in or on the skin.

Abstract: In light therapy apparatus is defined to include a UV light source secured to a casing. A shroud is placed over an exposed portion of the UV light source and is secured or attached around the perimeter of the casing end. Since the UV light source can generate a significant amount of heat, the casing includes an internal fan. Various tubing configurations may be used to help direct the air flow from the fan around the UV light source. In addition, a vent opening in the shroud was found to reduce the temperature of the shroud to prevent damage to a person using the apparatus.

Abstract: In one embodiment there is provided a system for delivering UV-light under a patient's tongue. The system includes a UV-light source in communication with a pair of tubes and a U-shaped double trough mouth piece with upper and lower troughs adapted to engage upper and lower teeth. The upper and lower troughs being interconnected by a relatively flat base surface. A pair of windowed apertures are centrally located in the double trough region and extend from the front to the rear of the double trough region. Each windowed aperture includes a pair of openings extending out through the lower base surface to accommodate the pair of tubes, such that the tips of the tubes are capable of extending through the openings and exiting through the lower base surface.

Abstract: In one embodiment there is provided a system for light therapy. The system includes a light guide transmission device having at least one UV bulb for dispersing UV light a light guide cable to a light guide terminating end, an optical capturing device operable to receive an image from a lens positioned at an optical cable terminating end, and a fluid delivery/suction device along a flexible hose. Each of the cables being inserted into a probe cable having a tip adapted for use internally or externally with a patient. Further the system includes a single controller in communication with and for controlling the functionality of the light guide transmission device, the optical capturing device, and the fluid delivery/suction device.

Abstract: An light therapy apparatus is defined to include a UV light source secured to a casing. A shroud is placed over an exposed portion of the UV light source and is secured or attached around the perimeter of the casing end. Since the UV light source can generate a significant amount of heat, the casing includes an internal fan. Various tubing configurations may be used to help direct the air flow from the fan around the UV light source. In addition, a vent opening in the shroud was found to reduce the temperature of the shroud to prevent damage to a person's user the apparatus.

Abstract: A device for providing light, preferably UV light to infants and/or children. The device comprises a housing, inside the housing are one or more light sources adapted to emit light at a therapeutic wavelength or wavelengths. A series of apertures in the housing are adapted to align a plurality of light guides with the light source(s). The light guides conduct light to the patient. The light guides are preferably attached to a light guide holding element. The holding element is preferably a panel which is adjustably placed above the patient. The light guides can either provide light directly to the patient or the panel can be the light providing surface.

Abstract: Ultraviolet light is applied to an animal's blood while that blood remains in the body. The UV light is applied sublingually or directly to the blood. One of more light guides is used in connection with a bridle to help directed the ends of the light guide under the animal's tongue.