Abstract: A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes.

Abstract: A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes.

Abstract: Methods are provided for treating or preventing human immunodeficiency virus-1 (HIV-1) or human immunodeficiency virus-2 (HIV-2) in a virologically suppressed patient in need thereof comprising switching the patient from an antiretroviral treatment regimen comprising at least three antiretroviral agents to a treatment regimen comprising only two antiretroviral agents. In one aspect the two treatment regimen consists of dolutegravir, rilpivirine and at least one pharmaceutically acceptable excipient, diluent or carrier. In another aspect of the invention, there is provided a multilayer tablet comprising dolutegravir or a pharmaceutically acceptable salt thereof and rilpivirine or a pharmaceutically acceptable salt thereof.

Abstract: A laundry treating appliance for treating laundry items according to an automatic cycle of operation can include a cabinet defining an interior and having an access opening providing access to the interior. A tub can be located within the interior and can at least partially define a liquid chamber. A drum is rotatably mounted within the liquid chamber and at least partially defines a treating chamber. A clothes mover is located within the treating chamber and rotatable about a vertical axis. The clothes mover can include a base and a barrel.

Abstract: A laundry treating appliance for treating laundry items according to an automatic cycle of operation can include a cabinet defining an interior and having an access opening providing access to the interior. A tub can be located within the interior and can at least partially define a liquid chamber. A drum is rotatably mounted within the liquid chamber and at least partially defines a treating chamber. A clothes mover is located within the treating chamber and rotatable about a vertical axis. The clothes mover can include a base and a barrel.

Abstract: A method for correlation attributes of mature mammals tissue to pre-pubescent mammals is provided. The method comprises providing a biopsy needle with a bore diameter of at least 0.9081 mm (20 gauge) to less than 2.413 mm (13 gauge) with a specimen notch, of at least 2 mm to no more than 16 mm; inserting the needle into said mammalian tissue of a pre-pubescent living mammal and extracting a sample tissue.

Abstract: A scanning apparatus includes an illuminator for illuminating a portion of a document to be scanned. The illuminator includes at least one light source and an optical element positioned to redirect light emitted by the light source. A phosphor material is disposed to intercept at least a portion of the light redirected by the optical element. A photosensitive device is positioned to receive light reflected from the document for recording an image of the document.

Abstract: This is a ceramic disk PTC and heater assembly, and a method for attaching one to the other, the combination useful in the heating elements of solid ink printing apparatus. The ceramic disk PTC attachment method is made up of a low melting temperature solder and a high operating temperature adhesive. The solder attaches the disk to a substrate, and provides a low resistance electrical and thermal bond to the substrate. The adhesive is used to substantially completely encircle the solder, containing the solder when melted, and keeping the PTC attached when the solder is melted. The adhesive can also partially encircle the solder to a degree sufficient to substantially prevent substantial escape of molten solder from the attachment area.

Abstract: Disclosed are treatment agents and methods of treatment utilizing the agents directed toward diseases in which the disease causing pathogen includes ?6?1 integrin receptors and/or ?6?4 integrin receptors on the surface of the pathogen. In one embodiment, the disease can be breast cancer. The therapeutic agents disclosed include a polypeptide comprising at least a portion of the G domain of the laminin-5 ?3 chain that has been shown to bind ?6?1 integrin receptors and ?6?4 integrin receptors. In one embodiment, the therapeutic agents can be fused or chimeric materials in which the laminin-5 ?3 chain polypeptide has been chemically bound to another material that can be useful in the destruction or neutralization of the pathogen.

Abstract: Methods of forming proteinaceous products such as cell culture supplement capable of supporting the growth and culturing of cells, tissue, and organs, are generally disclosed. One method generally provides for the collection of the internal tissue of an animal, such as a bovine, and the processing of the internal tissue to degrade and/or lyse the tissue components. A cell culture supplement or other proteinaceous product can be prepared from the processed tissue. A proteinaceous product can include, for example, a complete protein profile of the tissue or only certain biological factors extracted from the tissue. Collected internal tissue can be lymphatic tissue such as the supramammary glands of a dairy or beef cow or the thymus gland of a veal calf.

Abstract: This is a ceramic disk PTC and heater assembly, and a method for attaching one to the other, the combination useful in the heating elements of solid ink printing apparatus. The ceramic disk PTC attachment method is made up of a low melting temperature solder and a high operating temperature adhesive. The solder attaches the disk to a substrate, and provides a low resistance electrical and thermal bond to the substrate. The adhesive is used to substantially completely encircle the solder, containing the solder when melted, and keeping the PTC attached when the solder is melted. The adhesive can also partially encircle the solder to a degree sufficient to substantially prevent substantial escape of molten solder from the attachment area.

Abstract: A radioimmunoassay method for determining the quantity of an analyte of interest in a sample is disclosed. The analyte of interest may be an antigen or other chemical entity. A known antibody to the antigen or other entity is employed and is conjugated to a functionalized nanoparticle. Because of the high surface area presented by the present nanoparticle—antibody conjugates, the present radioimmunoassay method is particularly suited for the qualitative and quantitative analysis of low molecular weight chemicals.

Abstract: A scanning apparatus includes an illuminator for illuminating a portion of a document to be scanned. The illuminator includes at least one light source and an optical element positioned to redirect light emitted by the light source. A phosphor material is disposed to intercept at least a portion of the light redirected by the optical element. A photosensitive device is positioned to receive light reflected from the document for recording an image of the document.

Abstract: A system and methods for automatically adjusting pump operating parameters for at least one pump to accommodate solids encountered during a pumping operation. The output signal of a level sensor may be monitored so as to detect and account for variations therein. The power draw of the pump may also be monitored so as to detect and account for the presence of solids.

Abstract: A system and methods for automatically adjusting pump operating parameters for at least one pump to accommodate solids encountered during a pumping operation. The output signal of a level sensor may be monitored so as to detect and account for variations therein. The power draw of the pump may also be monitored so as to detect and account for the presence of solids.

Abstract: Gallic acid is a useful sweetener for foods, beverages and medicaments.