Patents by Inventor Thomas Randall Lee

Thomas Randall Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Metal nanoparticles functionalized with rationally designed coatings and uses thereof
    Patent number: 8470442
    Abstract: The present invention provides a composition and method for functionalizing nanoparticles that enables them to undergo reversible aggregation/deaggregation. The aggregation properties of this new system are reversible and readily monitored by optical absorbance measurements with the possibility of electrical and/or magnetic monitoring as well. The outer portion of the coating material is functionalized with polyethylene glycol (PEG) entities that facilitate biocompatibility and stability both in solution and in the solid state. Also provided are nanoparticles functionalized with rationally designed free radical initiators to effect tailored polymer growth from the surface. These systems may be used for a broad variety of applications, including biosensing with real-time feedback.
    Type: Grant
    Filed: April 5, 2010
    Date of Patent: June 25, 2013
    Assignee: University of Houston System
    Inventors: Thomas Randall Lee, Hye Hun Park, Nam Hoon Kim
  • Metal Nanoparticles functionalized with rationally designed coatings and uses thereof
    Publication number: 20100255311
    Abstract: The present invention provides a composition and method for functionalizing nanoparticles that enables them to undergo reversible aggregation/deaggregation. The aggregation properties of this new system are reversible and readily monitored by optical absorbance measurements with the possibility of electrical and/or magnetic monitoring as well. The outer portion of the coating material is functionalized with polyethylene glycol (PEG) entities that facilitate biocompatibility and stability both in solution and in the solid state. Also provided are nanoparticles functionalized with rationally designed free radical initiators to effect tailored polymer growth from the surface. These systems may be used for a broad variety of applications, including biosensing with real-time feedback.
    Type: Application
    Filed: April 5, 2010
    Publication date: October 7, 2010
    Inventors: Thomas Randall Lee, Hye Hun Park, Nam Hoon Kim