Abstract: The invention concerns novel streptavidin muteins. In one embodiment such a the mutein (a) contains at least two cysteine residues in the region of the amino acid positions 44 to 53 with reference to the amino acid sequence of wild type streptavidin as set forth at SEQ ID NO: 212 and (b) has a higher binding affinity than (i) a streptavidin mutein “1” (SEQ ID NO: 112) that comprises the amino acid sequence Val44-Thr45-Ala46-Arg47 (SEQ ID NO: 98), or (ii) wild type-streptavidin of which amino acid residues 14 to 139 are shown as SEQ ID NO: 212 for peptide ligands comprising the amino acid sequence Trp-Ser-His-Pro-Gln-Phe-Glu-Lys (SEQ ID NO: 100).

Abstract: A device for administering a fluid is provided, with a cylinder (16, 116) which has an open dispensing end (17), a piston (36) which is displaceable between a front and rear end position in the cylinder (16, 116) and is connected to a piston rod (35) that protrudes along a first direction beyond a rear end of the cylinder (16, 116) opposite the open dispensing end (17) and is guided in a receiving block (10), a nonreturn valve (18) closing the open dispensing end (17), and a tensioning device (S) which is connected to the piston rod (35, 135) and is arranged in the receiving block (10). The tensioning device (S) has a ramp (52) which is rotatable by means of a motor (12) and has a ramp track (53) extending along a helical line, wherein the ramp track (53) ascends from a first plateau along a region of inclination (S1, S2) to a second plateau and descends from the second plateau to the first plateau via a transition flank (46).

Abstract: The present disclosure relates to a method for starting up or servicing a field device: reading unique identification information assigned to the field device via a static code by means of a reading and/or operating tool; optically reading diagnostic information stored in the field device and which relates to at least one current and/or past event assigned to the field device, via a dynamic code generated by the field device by means of the reading and/or operating tool; transmitting the identification and diagnostic information from the reading and/or operating tool to a cloud-based service platform, transmitting device and/or application-specific information for remedying the event characterized by the diagnostic information from the cloud-based service platform to the reading and/or operating tool, and eliminating the event or effects of the event using the transmitted device-specific and/or application-specific information.

Abstract: Process for making a powder or granule containing (A) at least one chelating agent selected from alkali metal salts of methyl glycine diacetic acid (MGDA) and of iminodisuccinic acid (IDS), (B) at least one compound of general formula (I a) or (I b) wherein A1 is selected from (CH2)a wherein the variable a is in the range of from 4 to 20, e is selected from zero and 1, and R1 being the same or different and selected from O—C1-C10-alkyl and C1-C10-alkyl, and, optionally, (C) at least one homo- or copolymer of (meth)acrylic acid, partially or fully neutralized with alkali, said process comprising the steps of (a) providing an aqueous solution or slurry containing chelating agent (A) and said compound (B) and, if applicable, (co)polymer (C), with a pH value in the range of from 10 to 12, (b) removing most of said water by spray drying or spray granulation.

Abstract: A process for making a complexing agent with an enantiomeric excess of at least 60%, wherein said process comprises the following steps: (a) reacting an aqueous slurry of alanine with an enantiomeric excess of at least 60% with formaldehyde and hydrocyanic acid, thereby forming an aqueous solution of alanine-bisacetonitrile, (b) saponifying the alanine-bisacetonitrile from step (a) by combining the aqueous solution obtained in step (a) with an aqueous solution of alkali metal hydroxide.

Abstract: An illustrative example elevator assembly includes a header beam and a first elevator cab supported by the header beam. A plurality of vertically oriented rods extend beneath the first elevator cab. A horizontally oriented mid-beam is coupled to a first one of the rods near a first end of the mid-beam and coupled to a second one of the rods near a second end of the mid-beam. A second elevator cab is situated beneath the first elevator cab and beneath the mid-beam. At least one linear actuator is supported at least partially on the mid-beam. The linear actuator selectively causes vertical movement of the second elevator cab relative to the rods.

Abstract: An illustrative example embodiment of an elevator system includes a plurality of components respectively configured for at least one function during operation of the elevator system. A plurality of sensors are each associated with at least one of the components. Each sensor senses at least one characteristic of an actual performance of an associated one of the components. A processor is configured to receive respective indications from the sensors regarding the actual performance of the associated components, determine a difference between the actual performance and a desired performance of any of the components based on the respective indications, and determine an adjustment to the operation of the elevator system based upon the determined difference.

Abstract: A brake system for a vehicle having at least two axles. The brake system includes a hydraulic deceleration unit with a motorized brake pressure buildup device, a first and second wheel brake cylinder which can be mounted on a first and second wheel of a first axle of the vehicle. The first wheel brake cylinder is hydraulically connected to the motorized brake pressure buildup device via a first pressure control valve, and the second wheel brake cylinder is hydraulically connected to the motorized brake pressure buildup device via a second pressure control valve. The brake system includes an electromechanical deceleration unit having a first electromechanical wheel brake cylinder which can be mounted on a first wheel of a second axle of the vehicle and a second electromechanical wheel brake cylinder which can be mounted on a second wheel of the second axle.

Abstract: A system for elevator door sensor fusion, fault detection, and service notification is provided. The system includes a processor and a memory including computer-executable instructions that, when executed by the processor, cause the processor to perform operations. The operations include monitoring outputs of a plurality of sensors. It is determined whether the outputs of the plurality of sensors follow an expected pattern. Based at least in part on determining that the outputs of the plurality of sensors do not follow the expected pattern: identifying a sensor in the plurality of sensors that is not following the expected pattern, and transmitting a notification indicating that the sensor is exhibiting unexpected behaviour.

Abstract: The present invention relates to a membrane electrode unit comprising a polymer membrane doped with a mineral acid as well as two electrodes, characterized in that the polymer membrane comprises at least one polymer with at least one nitrogen atom and at least one electrode comprises a catalyst which is formed from at least one precious metal and at least one metal less precious according to the electrochemical series.

Abstract: The present application is related to a container made of a polymer and containing a single unit dose of a detergent composition. The detergent composition contains at least two complexing agents (A) dissolved in an aqueous medium. The complexing agents (A) are (A1) at least one alkali metal salt of methyl glycine diacetic acid (MGDA), and (A2) at least one alkali metal salt of glutamic acid diacetic acid (GLDA). The complexing agents (A1) and (A2) are partially neutralized with alkali and the weight ratio of (A1) and (A2) ranges from 1:9 to 9:1. The aqueous medium contains at least 25% by weight of water relative to the entire liquid phase.

Abstract: Techniques and devices are disclosed for forming wettable flanks on no-leads semiconductor packages. A lead frame assembly may include a plurality of leads, each lead including a die surface and a plating surface, and an integrated circuit die arranged on the die surface. The plating surface for each of the leads may be plated with an electrical plating. A connecting film may be applied and lead frame assembly may be singulated into individual semiconductor packages by a series of cuts through each of the plurality of leads and the electrical plating of each of the plurality of leads to a depth up to or through a portion of the connecting film to create a channel exposing lead sidewalls of each of the plurality of leads. The lead sidewalls of each of the plurality of leads may be plated with a second electrical plating and the connecting film may be removed.

Abstract: An electropneumatic brake system, for a commercial vehicle which is provided for pulling a trailer, includes at least one service brake circuit configured to activate service brake actuators, a parking brake circuit having parking brake actuators on at least one axle, a trailer brake circuit configured to provide a trailer brake pressure at a trailer brake pressure port, and a manually actuatable operating unit in a driver's cab. The manually actuatable operating unit has a first operating element and a second operating element. In the case of actuation of the first operating element when the vehicle is driving, the parking brake actuators are activated and a trailer brake pressure is output at the trailer brake pressure port. In the case of actuation of the second operating element when the vehicle is driving, only a trailer brake pressure is output.

Abstract: A cartridge and a method for enriching drinking water with silicon are provided. A cross-linked silicic acid is used, which can be mixed with a cation exchanger that is preferably loaded with hydrogen and/or with alkalizing agents and/or with activated carbon. Silicon can be released into the water via the silicic acid.

Abstract: A sensor component for a transmission of a motor vehicle is provided. The sensor component includes a printed circuit board having a first printed circuit board region and a second printed circuit board region. The first printed circuit board region is delimited from the second printed circuit board region by a milled groove and is angled with respect to the second printed circuit board region along the milled groove. A sensor, such as a magnetoresistive sensor or a Hall sensor, is arranged in or on the first printed circuit board region. A pre-assembly arrangement and a method for producing such a sensor component are also provided.

Abstract: A dynamoelectric rotary machine includes a stator, which has a winding system arranged in grooves disposed between teeth of a magnetically conductive body and a winding head on the end faces of the stator in each case. A rotor with a cage ring is arranged rotatably about an axis and during operation of the dynamoelectric rotary machine is in electromagnetic interaction in a motor-driven or generator-driven manner with the winding system of the stator arranged in the grooves by way of an air gap. Comb-type elements are disposed on the end faces of the stator. The comb-type elements assume an extensive intermediate space between the winding system projecting from the end faces of the stator, so that tonal noises which are produced during operation of such an electric machine are at least reduced.

Abstract: A device for administering a fluid is provided, with a cylinder (16, 116) which has an open dispensing end (17), a piston (36) which is displaceable between a front and rear end position in the cylinder (16, 116) and is connected to a piston rod (35) that protrudes along a first direction beyond a rear end of the cylinder (16, 116) opposite the open dispensing end (17) and is guided in a receiving block (10), a nonreturn valve (18) closing the open dispensing end (17), and a tensioning device (S) which is connected to the piston rod (35, 135) and is arranged in the receiving block (10). The tensioning device (S) has a ramp (52) which is rotatable by means of a motor (12) and has a ramp track (53) extending along a helical line, wherein the ramp track (53) ascends from a first plateau along a region of inclination (S1, S2) to a second plateau and descends from the second plateau to the first plateau via a transition flank (46).

Abstract: The invention relates to an actuator having a drive device which drives a drive shaft, a first actuating element which is operatively connected to the drive shaft, a spring element which can be supported on one side on a housing component of the actuator and is supported on the other side on a second actuating element which is configured for stressing the spring element, wherein a rotational element which can be driven by means of the drive shaft and is rotatably mounted is provided. According to the invention, a further actuating element for actuating a switching device is provided, which further actuating element is operatively connected to the first actuating element, and a transmission device with a transmission element is provided between the first actuating element and the actuating element of the switching device.

Abstract: The present invention relates to a membrane electrode unit comprising a polymer membrane doped with a mineral acid as well as two electrodes, characterized in that the polymer membrane comprises at least one polymer with at least one nitrogen atom and at least one electrode comprises a catalyst which is formed from at least one precious metal and at least one metal less precious according to the electrochemical series.

Abstract: An atmospheric suit includes a torso portion with one or more layers, and fibers of a first material arranged in each of the one or more layers. Optical fibers are interspersed with the fibers of the first material in each of the one or more layers.