Abstract: This invention relates to a synthetic method for the preparation of Compound 1 and precursors thereof. Compound 1 is prepared via reaction of isoxazole 2 with phenylether (R)-3-ONa.

Abstract: In one aspect, the disclosure relates to a compact membrane reactor for parahydrogen induced hyperpolarization, the reactor including an inner tube constructed of a semipermeable membrane, an outer tube surrounding the inner tube, and a means for controlling the magnetic field surrounding the outer tube. In some aspects, multiple compact membrane reactors can be arranged in parallel. In other aspects, the compact membrane reactor is equipped with a mechanism for magnetic field control. Also disclosed are fluid handling systems and sample preparation systems comprising the compact membrane reactors disclosed herein. The compact membrane reactor can be operated in a batch mode, a stopped-flow mode, or a continuous flow mode and can be configured to work with existing NMR spectrometers and MRI instruments.

Abstract: Systems and methods of quantum sensing include depositing a sample volume onto an ensemble of quantum defects, hyperpolarizing spins in the sample volume, performing a sensing sequence, and reading out information regarding electronic spin states of the quantum defects in the ensemble of quantum defects, which sense the hyperpolarized spins in the sample volume.

Abstract: Provided are methods for nuclear spin polarization enhancement via signal amplification by reversible exchange at very low magnetic fields.

Abstract: Provided are methods for nuclear spin polarization enhancement via signal amplification by reversible exchange at very low magnetic fields. The spin polarization is hyperpolarization of isotopically enriched heteronuclei by using a catalyst and parahydrogen to create a complex using iridium and applying magnetic fields in the microtesia range to transfer the spin order from parahydrogen to the complex.

Abstract: Provided are methods for nuclear spin polarization enhancement via signal amplification by reversible exchange at very low magnetic fields. The spin polarization is hyperpolarization of isotopically enriched heteronuclei by using a catalyst and parahydrogen to create a complex using iridium and applying magnetic fields in the microtesia range to transfer the spin order from parahydrogen to the complex.

Abstract: Provided are methods for nuclear spin polarization enhancement via signal amplification by reversible exchange at very low magnetic fields.

Abstract: A system for recognizing objects is comprised of: 1) a camera that has a lens which is uncovered; 2) a housing which encloses the camera, and has a window for the lens; 3) a rotating means, which is inside of the housing and which carries the camera, for receiving electronic control signals and rotating the camera at different angles in response thereto; and, 4) a control means for generating the electronic control signals such that the rotating means selectively points the camera lens -a) through the window at any one of several predetermined angles, and b) inside of the housing at the surface for calibrating the camera. With this system, the objects that are recognized can be human faces at different heights relative to the window in the housing. By pointing the camera lens inside of the housing, the lens is protected from damage even though it is not covered; and a calibration surface inside of the housing enables the camera to be calibrated while the lens is protected.