Patents by Inventor Thomas Thomasen Durhuus

Thomas Thomasen Durhuus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ORAL CARE COMPOSITION COMPRISING A FRUCTANASE
    Publication number: 20230332124
    Abstract: The present invention relates to an oral care composition comprising a fructanase, use of said composition as medicaments, use of said composition in treatment of oral disease, methods of treatment comprising administering said composition to a human or animal subject, methods of removing biofilm comprising contacting the biofilm with said composition, kits of parts comprising said composition, and fructanases.
    Type: Application
    Filed: August 23, 2021
    Publication date: October 19, 2023
    Applicant: Novozymes A/S
    Inventors: Dorotea Raventos Segura, Lorena González Palmén, Jesper Salomon, Mark Dominique Morant, Mette Rose Joergensen, Thomas Thomasen Durhuus, Manish Kumar Tiwari
  • Metabolically engineered cells for the production of pinosylvin
    Patent number: 9725743
    Abstract: A genetically engineered micro-organism having an operative metabolic pathway producing cinnamoyl-CoA and producing pinosylvin therefrom by the action of a stilbene synthase is used for pinosylvin production. Said cinnamic acid may be formed from L-phenylalanine by a L-phenylalanine ammonia lyase (PAL) which is one accepting phenylalanine as a substrate and producing cinammic acid therefrom, preferably such that if the PAL also accepts tyrosine as a substrate and forms coumaric acid therefrom, the ratio Km(phenylalanine)/Km(tyrosine) for said PAL is less than 1:1 and if said micro-organism produces a cinammate-4 -hydroxylase enzyme (C4H), the ratio Kcat(PAL)/Kcat(C4H) is at least 2:1.
    Type: Grant
    Filed: January 2, 2013
    Date of Patent: August 8, 2017
    Assignee: Evolva SA
    Inventors: Michael Katz, Jochen Forster, Helga David, Hans Peter Schmidt, Malin Sendelius, Sara Peterson Bjorn, Thomas Thomasen Durhuus
  • Metabolically Engineered Cells For The Production of Pinosylvin
    Publication number: 20140024862
    Abstract: A genetically engineered micro-organism having an operative metabolic pathway producing cinnamoyl-CoA and producing pinosylvin therefrom by the action of a stilbene synthase is used for pinosylvin production. Said cinnamic acid may be formed from L-phenylalanine by a L-phenylalanine ammonia lyase (PAL) which is one accepting phenylalanine as a substrate and producing cinammic acid therefrom, preferably such that if the PAL also accepts tyrosine as a substrate and forms coumaric acid therefrom, the ratio Km(phenylalanine)/Km(tyrosine) for said PAL is less than 1:1 and if said micro-organism produces a cinammate-4-hydroxylase enzyme (C4H), the ratio Kcat(PAL)/Kcat(C4H) is at least 2:1.
    Type: Application
    Filed: January 2, 2013
    Publication date: January 23, 2014
    Inventors: Michael Katz, Jochen Forster, Helga David, Hans Peter Schmidt, Malin Sendelius, Sara Peterson Bjorn, Thomas Thomasen Durhuus
  • Metabolically engineered cells for the production of pinosylvin
    Patent number: 8343739
    Abstract: A genetically engineered micro-organism having an operative metabolic pathway producing cinnamoyl-CoA and producing pinosylvin therefrom by the action of a stilbene synthase is used for pinosylvin production. Said cinnamic acid may be formed from L-phenylalanine by a L-phenylalanine ammonia lyase (PAL) which is one accepting phenylalanine as a substrate and producing cinammic acid therefrom, preferably such that if the PAL also accepts tyrosine as a substrate and forms coumaric acid therefrom, the ratio Km(phenylalanine)/Km(tyrosine) for said PAL is less than 1:1 and if said micro-organism produces a cinammate-4-hydroxylase enzyme (C4H), the ratio Kcat(PAL)/Kcat(C4H) is at least 2:1.
    Type: Grant
    Filed: July 19, 2007
    Date of Patent: January 1, 2013
    Assignee: Fluxome Sciences A/S
    Inventors: Michael Katz, Jochen Förster, Helga David, Hans Peter Schmidt, Malin Sendelius, Sara Peterson Bjørn, Thomas Thomasen Durhuus
  • METABOLICALLY ENGINEERED CELLS FOR THE PRODUCTION OF PINOSYLVIN
    Publication number: 20090317881
    Abstract: A genetically engineered micro-organism having an operative metabolic pathway producing cinnamoyl-CoA and producing pinosylvin therefrom by the action of a stilbene synthase is used for pinosylvin production. Said cinnamic acid may be formed from L-phenylalanine by a L-phenylalanine ammonia lyase (PAL) which is one accepting phenylalanine as a substrate and producing cinammic acid therefrom, preferably such that if the PAL also accepts tyrosine as a substrate and forms coumaric acid therefrom, the ratio Km(phenylalanine)/Km(tyrosine) for said PAL is less than 1:1 and if said micro-organism produces a cinammate-4-hydroxylase enzyme (C4H), the ratio Kcat(PAL)/Kcat(C4H) is at least 2:1.
    Type: Application
    Filed: July 19, 2007
    Publication date: December 24, 2009
    Applicant: FLUXOME SCIENCES A/S
    Inventors: Michael Katz, Jochen Förster, Helga David, Hans Peter Schmidt, Malin Sendelius, Sara Peterson Bjørn, Thomas Thomasen Durhuus