Abstract: A fabric treatment composition that includes at least one zeta potential modifier and a hydrophobic agent with a melting point or glass transition temperature below 100° C. that imparts fabric protection benefits, including improved stain resistance, oil repellency, water repellency, softness, wrinkle and damage resistance, and better handfeel to treated fabrics. Particularly preferred compositions include at least one zeta potential modifier in an amount sufficient to adjust the zeta potential of the composition to be positive and greater than zero millivolts. Particularly preferred compositions also include a fluoropolymer. The composition can be used as a pretreatment prior to washing, through soaking or direct spray application, or added to the wash or rinse cycle of an automatic washing machine, or used prior to or during the drying cycle of an automatic drying machine or refresher machine, or used prior to or in conjunction with an ironing device.