Patents by Inventor Thu A. Le
Thu A. Le has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11800867Abstract: The invention relates to biting arthropod repellent compositions comprising nootkatone. The application also relates to a method of repelling said biting arthropods by application of the nootkatone composition to a hard or soft surface, to a method of treating an arthropod infestation and to a method of reducing the transmission of a parasite or disease pathogen spread by a biting arthropod using the nootkatone composition.Type: GrantFiled: November 12, 2021Date of Patent: October 31, 2023Assignee: EVOLVA SAInventors: Jean Davin Amick, Bryan N. Julien, Kim Thu Le Greenbaum
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Publication number: 20230074790Abstract: A method of allocating space on a spectrum on which information is transmitted, to information to be transmitted, the method comprising: identifying carrier frequencies and bandwidths of information being transmitted on the spectrum, determining an optimal carrier frequency and bandwidth for the information to be transmitted based on the carrier frequencies and bandwidths of information being transmitted on the spectrum; transmitting the information to be transmitted using modulation at the identified optimal carrier frequency and bandwidth.Type: ApplicationFiled: August 22, 2022Publication date: March 9, 2023Inventors: Alejandro Garcia Gener, Hector Palop, Thu Le Thi Anh Pham
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Publication number: 20230072476Abstract: A method of analysing a spectrum on which information is transmitted, comprising: determining each different type of modulation used for transmitting the information across the spectrum, for each determined modulation, identifying its carrier frequency and its bandwidth, defining characteristics of usage of the spectrum in terms of the determined modulations and their corresponding carrier frequencies and bandwidths.Type: ApplicationFiled: August 22, 2022Publication date: March 9, 2023Inventors: Alejandro Garcia Gener, Hector Palop, Thu Le Thi Anh Pham
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Patent number: 11524895Abstract: The present invention relates to a method for producing tetrahydridoborate salts with high efficiency at low cost. The method for the production of metal borohydride salts according to the present invention comprises the steps of providing an anhydrous metal borate salt and milling the anhydrous metal borate salt in the presence of a metal material based on magnesium or magnesium alloys in a hydrogen atmosphere at a temperature and for a time sufficient to produce the metal borohydride salt. In another embodiment of the invention, the method for the production of metal borohydride salts according to the present invention comprises the steps of providing an hydrated metal borate salt and milling the hydrated metal borate salt in the presence of a metal material based on magnesium or magnesium alloys in an inert gas atmosphere at a temperature and for a time sufficient to produce the metal borohydride salts.Type: GrantFiled: May 8, 2020Date of Patent: December 13, 2022Assignee: Helmholtz-Zentrum hereon GmbHInventors: Claudio Pistidda, Thi Thu Le, Julián Puszkiel, Klaus Horst Taube, Martin Dornheim, Thomas Klassen
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Patent number: 11376305Abstract: Both purinergic signaling through nucleotides such as ATP and noradrenergic signaling through molecules such as norepinephrine regulate vascular tone and blood pressure. Pannexin1 (Panx1), which forms large-pore, ATP-releasing channels, is present in vascular smooth muscle cells in peripheral blood vessels and participates in noradrenergic responses. Using pharmacological approaches and mice conditionally lacking Panx1 in smooth muscle cells, we found that Panx1 contributed to vasoconstriction mediated by the ?1 adrenoreceptor (?1AR), whereas vasoconstriction in response to serotonin or endothelin-1 was independent of Panx1. Analysis of the Panx1-deficient mice showed that Panx1 contributed to blood pressure regulation especially during the night cycle when sympathetic nervous activity is highest. Using mimetic peptides and site-directed mutagenesis, we identified a specific amino acid sequence in the Panx1 intracellular loop that is essential for activation by ?1AR signaling.Type: GrantFiled: April 12, 2019Date of Patent: July 5, 2022Assignee: University of Virginia Patent FoundationInventors: Brant E. Isakson, Marie Billaud, Leon J. DeLalio, Thu Le
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Publication number: 20220132841Abstract: The invention relates to biting arthropod repellent compositions comprising nootkatone. The application also relates to a method of repelling said biting arthropods by application of the nootkatone composition to a hard or soft surface, to a method of treating an arthropod infestation and to a method of reducing the transmission of a parasite or disease pathogen spread by a biting arthropod using the nootkatone composition.Type: ApplicationFiled: November 12, 2021Publication date: May 5, 2022Inventors: Jean Davin Amick, Bryan N. Julien, Kim Thu Le Greenbaum
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Patent number: 11191266Abstract: The invention relates to biting arthropod repellent compositions comprising nootkatone. The application also relates to a method of repelling said biting arthropods by application of the nootkatone composition to a hard or soft surface, to a method of treating an arthropod infestation and to a method of reducing the transmission of a parasite or disease pathogen spread by a biting arthropod using the nootkatone composition.Type: GrantFiled: March 24, 2017Date of Patent: December 7, 2021Inventors: Jean Davin Amick, Bryan N. Julien, Kim Thu Le Greenbaum
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Publication number: 20200361769Abstract: The present invention relates to a method for producing tetrahydridoborate salts with high efficiency at low cost. The method for the production of metal borohydride salts according to the present invention comprises the steps of providing an anhydrous metal borate salt and milling the anhydrous metal borate salt in the presence of a metal material based on magnesium or magnesium alloys in a hydrogen atmosphere at a temperature and for a time sufficient to produce the metal borohydride salt. In another embodiment of the invention, the method for the production of metal borohydride salts according to the present invention comprises the steps of providing an hydrated metal borate salt and milling the hydrated metal borate salt in the presence of a metal material based on magnesium or magnesium alloys in an inert gas atmosphere at a temperature and for a time sufficient to produce the metal borohydride salts.Type: ApplicationFiled: May 8, 2020Publication date: November 19, 2020Applicant: Helmholtz-Zentrum Geesthacht Zentrum für Material-und Küstenforschung GmbHInventors: Claudio Pistidda, Thu Thu Le, Julián Puszkiel, Klaus Horst Taube, Martin Dornheim, Thomas Klassen
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Patent number: 10785884Abstract: An in-wall amplifier assembly includes a wireless communication device and an amplifier located inside a first housing configured for in-wall installation, with the amplifier configured to amplify the audio output from the wireless communication device and supply it to external speakers. An AC/DC adapter located in a second housing can be connected thereto to supply DC power to the amplifier and wireless communication device. The wireless communication device can be removably accommodated in a faceplate of the first housing and held in place by a wall plate installed thereover. The amplifier can accept an external audio input from another source and automatically switch the amplified audio output between the output of the wireless communication device and the external audio input.Type: GrantFiled: January 14, 2019Date of Patent: September 22, 2020Inventors: Jimmy Lee Murray, Thu Le
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Publication number: 20200189921Abstract: The present invention relates to a preparation method of a matrix of rice husk silica for immobilizing enzyme wherein a rice husk silica is modified with APTES((3-aminopropyl)triethoxysilane) and glutaraldehyde, a matrix of rice husk silica for immobilizing enzyme prepared by said method, a rice husk silica-enzyme complex wherein enzyme is immobilized onto said matrix of rice husk silica and a preparation method of valuable substances using said rice husk silica-enzyme complex. The rice husk silica having a nanoporous structure cannot only facilitate diffusion of substrate during enzyme reaction but also can be utilized as a path through which intermediates from the consecutive enzyme reactions can travel. Therefore, it can be effectively utilized in preparing valuable substances.Type: ApplicationFiled: January 17, 2018Publication date: June 18, 2020Inventors: Ok Soo HAN, Chong Soo HAN, Bao Thu LE, Putheary NGIN
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Publication number: 20200016232Abstract: Both purinergic signaling through nucleotides such as ATP and noradrenergic signaling through molecules such as norepinephrine regulate vascular tone and blood pressure. Pannexin1 (Panx1), which forms large-pore, ATP-releasing channels, is present in vascular smooth muscle cells in peripheral blood vessels and participates in noradrenergic responses. Using pharmacological approaches and mice conditionally lacking Panx1 in smooth muscle cells, we found that Panx1 contributed to vasoconstriction mediated by the ?1 adrenoreceptor (?1AR), whereas vasoconstriction in response to serotonin or endothelin-1 was independent of Panx1. Analysis of the Panx1-deficient mice showed that Panx1 contributed to blood pressure regulation especially during the night cycle when sympathetic nervous activity is highest. Using mimetic peptides and site-directed mutagenesis, we identified a specific amino acid sequence in the Panx1 intracellular loop that is essential for activation by ?1AR signaling.Type: ApplicationFiled: April 12, 2019Publication date: January 16, 2020Applicant: University of Virginia Patent FoundationInventors: Brant E. Isakson, Marie Billaud, Leon J. DeLalio, Thu Le
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Patent number: 10457659Abstract: The present disclosure provides methods of increasing proliferation of adult salivary stem cells. The methods include contacting adult salivary stem cells in vivo, in vitro, or ex vivo with an aldehyde dehydrogenase (ALDH) agonist. Increasing proliferation of adult salivary stem cells can be carried out to provide for an increase in the number of adult salivary stem cells in an individual undergoing radiotherapy for head and neck cancer.Type: GrantFiled: April 26, 2012Date of Patent: October 29, 2019Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Che-Hong Chen, Daria Mochly-Rosen, Quynh-Thu Le
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Publication number: 20190223304Abstract: An in-wall amplifier assembly includes a wireless communication device and an amplifier located inside a first housing configured for in-wall installation, with the amplifier configured to amplify the audio output from the wireless communication device and supply it to external speakers. An AC/DC adapter located in a second housing can be connected thereto to supply DC power to the amplifier and wireless communication device. The wireless communication device can be removably accommodated in a faceplate of the first housing and held in place by a wall plate installed thereover. The amplifier can accept an external audio input from another source and automatically switch the amplified audio output between the output of the wireless communication device and the external audio input.Type: ApplicationFiled: January 14, 2019Publication date: July 18, 2019Applicant: 3M1S, LLCInventors: Jimmy Lee Murray, Thu Le
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Patent number: 10314883Abstract: Both purinergic signaling through nucleotides such as ATP and noradrenergic signaling through molecules such as norepinephrine regulate vascular tone and blood pressure. Pannexin1 (Panx1), which forms large-pore, ATP-releasing channels, is present in vascular smooth muscle cells in peripheral blood vessels and participates in noradrenergic responses. Using pharmacological approaches and mice conditionally lacking Panx1 in smooth muscle cells, we found that Panx1 contributed to vasoconstriction mediated by the ?1 adrenoreceptor (?1AR), whereas vasoconstriction in response to serotonin or endothelin-1 was independent of Panx1. Analysis of the Panx1-deficient mice showed that Panx1 contributed to blood pressure regulation especially during the night cycle when sympathetic nervous activity is highest. Using mimetic peptides and site-directed mutagenesis, we identified a specific amino acid sequence in the Panx1 intracellular loop that is essential for activation by ?1AR signaling.Type: GrantFiled: February 12, 2016Date of Patent: June 11, 2019Assignee: University of Virginia Patent FoundationInventors: Brant E. Isakson, Marie Billaud, Leon J. DeLalio, Thu Le
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Publication number: 20190098897Abstract: The invention relates to biting arthropod repellent compositions comprising nootkatone. The application also relates to a method of repelling said biting arthropods by application of the nootkatone composition to a hard or soft surface, to a method of treating an arthropod infestation and to a method of reducing the transmission of a parasite or disease pathogen spread by a biting arthropod using the nootkatone composition.Type: ApplicationFiled: March 24, 2017Publication date: April 4, 2019Inventors: Jean Davin Amick, Bryan N. Julien, Kim Thu Le Greenbaum
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Publication number: 20190060249Abstract: The present disclosure provides methods of increasing proliferation of adult salivary stem cells, methods of protecting adult salivary stem cells and improving salivary gland function. The methods include contacting adult salivary stem cells in vivo, in vitro, or ex vivo with a therapeutically effective amount of at least one isolated monoterpene and subjecting the adult salivary stem cells to radiation treatment. Increasing proliferation of adult salivary stem cells can be carried out to provide for an increase in the number of adult salivary stem cells and improve salivary gland function in an individual undergoing radiotherapy for head and neck cancer. The methods also include treating an individual with dry eye with a therapeutically effective amount of at least one isolated monoterpene.Type: ApplicationFiled: August 23, 2018Publication date: February 28, 2019Inventors: Julie Saiki, Che-Hong Chen, Quynh-Thu Le, Daria Mochly-Rosen
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Publication number: 20180028595Abstract: Both purinergic signaling through nucleotides such as ATP and noradrenergic signaling through molecules such as norepinephrine regulate vascular tone and blood pressure. Pannexin1 (Panx1), which forms large-pore, ATP-releasing channels, is present in vascular smooth muscle cells in peripheral blood vessels and participates in noradrenergic responses. Using pharmacological approaches and mice conditionally lacking Panx1 in smooth muscle cells, we found that Panx1 contributed to vasoconstriction mediated by the ?1 adrenoreceptor (?1AR), whereas vasoconstriction in response to serotonin or endothelin-1 was independent of Panx1. Analysis of the Panx1-deficient mice showed that Panx1 contributed to blood pressure regulation especially during the night cycle when sympathetic nervous activity is highest. Using mimetic peptides and site-directed mutagenesis, we identified a specific amino acid sequence in the Panx1 intracellular loop that is essential for activation by ?1AR signaling.Type: ApplicationFiled: February 12, 2016Publication date: February 1, 2018Applicant: University of Virginia Patent FoundationInventors: Brant E. Isakson, Marie Billaud, Leon J. DeLalio, Thu Le
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Publication number: 20140323520Abstract: The present disclosure provides methods of increasing proliferation of adult salivary stem cells. The methods include contacting adult salivary stem cells in vivo, in vitro, or ex vivo with an aldehyde dehydrogenase (ALDH) agonist. Increasing proliferation of adult salivary stem cells can be carried out to provide for an increase in the number of adult salivary stem cells in an indi vidual undergoing radiotherapy for head and neck cancer.Type: ApplicationFiled: April 26, 2012Publication date: October 30, 2014Applicant: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Che-Hong Chen, Daria Mochly-Rosen, Quynh-Thu Le
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Patent number: 8762977Abstract: Mobile device software is managed by providing an interface between a plurality of software module handlers and a plurality of software modules. The interface is invoked responsive to a software module event such as the installation, removal, activation or modification of a software module. The interface identifies the software module and a corresponding attribute list associated with the software module event. The attribute list specifies one or more actions to be taken by at least one of the software module handlers that enable the identified software module to provide one or more functions when invoked. The attribute list is provided to each software module handler identified in the list and each action specified in the list is taken by the corresponding software module handler. This way, the interface reliably manages the different software modules without being aware of the particular functions provided by the modules or the specific actions taken by the handlers.Type: GrantFiled: April 10, 2008Date of Patent: June 24, 2014Assignee: Telefonaktiebolaget L M Ericsson (publ)Inventors: Magnus Olsson, Björn Bjäre, Annika Brobach, Chi Thu Le, Louis Verhaard
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Publication number: 20120250536Abstract: The invention is directed to a method of preserving accuracy in dual-ended frame loss measurement system between a first node and a second node in a packet switching network, especially by Ethernet routers, switches and bridges supporting ITU-T Y.1731 dual-ended LM functionality by enhancing the behavior of dual-ended frame loss measurement to permit enabling and disabling the loss measurement at each node separately without incurring erroneous errors.Type: ApplicationFiled: March 31, 2011Publication date: October 4, 2012Applicant: ALCATEL-LUCENT CANADA INC.Inventors: Daniel Lafleur, Thu Le