Abstract: Aspects of the disclosure relate to systems, methods, and computing devices for managing the processing and execution of machine learning classifiers across a variety of platforms. Machine classifiers can be developed to process a variety of input datasets. In several embodiments, a variety of transformations can be performed on raw data to generate the input datasets. The raw data can be obtained from a disparate set of data sources each having its own data format. The generated input datasets can be formatted using a common data format and/or a data format specific for a particular machine learning classifier. A sequence of machine learning classifiers to be executed can be determined and the machine learning classifiers can be executed on one or more computing devices to process the input datasets. The execution of the machine learning classifiers can be monitored and notifications can be transmitted to various computing devices.

Abstract: A method for predicting a customer trust target metric includes receiving, from a business, a customer trust target metric definition defining a customer trust target metric customized by the business. The method also includes obtaining sentiment data representative of one or more interactions between a customer and the business. The sentiment data includes textual feedback data and non-textual metadata. The method also includes determining, using a natural language processing model, a sentiment score of the sentiment data. Further, the method includes predicting, using the sentiment score and the customer trust target metric definition, a respective customer trust target metric for a respective one of the one or more interactions between the customer and the business. The method also includes sending, to the business, the predicted respective customer trust target metric.

Abstract: A wideband dual-polarized hourglass-shaped with wedge antenna for a 3G/4G/5G base station is designed using characteristic mode analysis to adjust resonant frequencies. The proposed antenna has a wide bandwidth when adding two pairs of wedges on the radiator, yielding two linear polarizations ±45°, and fulfilling all the requirements of 3G/4G and 5G antenna elements. The antenna is mechanically designed and easy to fabricate with die-casting, thus saving cost since only a single die is required for mass fabrication with low errors and large quantities.

Abstract: The present invention images a heartbeat strength representing the strength of pulsations (beats) on a map as a new dynamics index different from the conventional waveform numerical value. A computation section according to the present invention obtains, from time-course changes of the blood flow map obtained as a result of computation of blood flow speed, a signal intensity at a fundamental frequency determined from time-series blood flow data within a predetermined region, and calculates a heartbeat strength which represents the strength of heartbeats on the basis of the signal intensity. A display section images and displays the heartbeat strength calculated by the heartbeat strength computation section. Also, the display section displays the heartbeat strength calculated by the heartbeat strength computation section by superimposing the heartbeat strength on a combined map created by averaging a plurality of blood flow maps arranged in a chronological order.

Abstract: The disclosure is directed to systems, methods, and apparatus, including non-transitory computer-readable media, for performing quota resolution on a cloud computing platform. A system can receive user account data from one or more user accounts representing a first user. The system can generate a plurality of features from the user account data characterizing interactions between the first user and the computing platform. From at least the plurality of features, the system can generate a score at least partially representing a predicted likelihood that the additional computing resources allocated to the first user account will be used in violation of one or more predetermined abusive usage parameters during a predetermined future time period.

Abstract: Aspects of the disclosure relate to systems, methods, and computing devices for managing the processing and execution of machine learning classifiers across a variety of platforms. Machine classifiers can be developed to process a variety of input datasets. In several embodiments, a variety of transformations can be performed on raw data to generate the input datasets. The raw data can be obtained from a disparate set of data sources each having its own data format. The generated input datasets can be formatted using a common data format and/or a data format specific for a particular machine learning classifier. A sequence of machine learning classifiers to be executed can be determined and the machine learning classifiers can be executed on one or more computing devices to process the input datasets. The execution of the machine learning classifiers can be monitored and notifications can be transmitted to various computing devices.

Abstract: Systems, methods, and apparatus, including computer-readable storage media storing executable instructions, for providing dynamic identity profiles are described. A dynamic user identity may be generated and updated in real time according to a user's interactions, interests, and various other suitable parameters. Contextual information, geo-fencing, beacon transmissions, and various other features may be used to acquire information that is included in the dynamic user identity and to provide more effective and intelligent interactions of the user with other devices based on the dynamic user identity.

Abstract: The present invention images a heartbeat strength representing the strength of pulsations (beats) on a map as a new dynamics index different from the conventional waveform numerical value. A computation section according to the present invention obtains, from time-course changes of the blood flow map obtained as a result of computation of blood flow speed, a signal intensity at a fundamental frequency determined from time-series blood flow data within a predetermined region, and calculates a heartbeat strength which represents the strength of heartbeats on the basis of the signal intensity. A display section images and displays the heartbeat strength calculated by the heartbeat strength computation section. Also, the display section displays the heartbeat strength calculated by the heartbeat strength computation section by superimposing the heartbeat strength on a combined map created by averaging a plurality of blood flow maps arranged in a chronological order.

Abstract: A computer-implemented method includes receiving a request for information indicative of venues that are located within a geographic region of interest, accessing user data for one or more users of a social networking platform, identifying, in the accessed user data, data indicative of one or more affirmative actions that are performed for the particular venue by at least one of the one or more users, and generating a popularity score for the particular venue, determining one or more popular venues, with a popular venue being associated with an increased popularity score relative to popularity scores of other of the multiple venues located with the geographic region of interest, and for a determined popular venue, generating data indicative of a type of user of the social networking platform who performs one or more affirmative actions for the determined popular venue.

Abstract: The Wrong Way Detection System includes detection stations deployed at each egress point along a tollway in addition to various locations along the tollway's mainline. The detection hardware communicates preferably via fiber optic network to a customized software platform housed at a centrally located Incident Management Center (IMC) of the system, where each site is monitored 24/7 in real time for wrong way vehicles. Once a vehicle is detected, operators at the IMC are able to immediately dispatch law enforcement officers and monitor the vehicle's whereabouts via CCTV cameras.

Abstract: Provided are a method, system, and article of manufacture for receiving an initial request from a first device to a second device. A response to the initial request is received from the second device to the first device. Each response and request received from the first device to the second device is processed by accessing the response or request from a packet encoded using a first communication protocol; generating a packet including the accessed response or request into a packet encoded using a second communication protocol; and transmitting the generated packet to the second device. Each response and request received from the second device to the first device is processed by accessing the response or request from a packet encoded using the second communication protocol; generating a packet including the accessed response or request into a packet encoded using the first communication protocol; and transmitting the generated packet to the second device.

Abstract: Disclosed are compounds of the formula I or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein W is a bond, —C(?S)—, —S(O)—, —S(O)2—, —C(?O)—, —O—, —C(R6)(R7)—, —N(R5)— or —C(?N(R5))—; X is —O—, —N(R5)— or —C(R6)(R7)—; provided that when X is —O—, U is not —O—, —S(O)—, —S(O)2—, —C(?O)— or —C(?NR5)—; U is a bond, —S(O)—, —S(O)2—, —C(O)—, —O—, —P(O)(OR15)—, —C(?NR5)—, —(C(R6)(R7))b— or —N(R5)—; wherein b is 1 or 2; provided that when W is —S(O)—, —S(O)2—, —O—, or —N(R5)—, U is not —S(O)—, —S(O)2—, —O—, or —N(R5)—; provided that when X is —N(R5)— and W is —S(O)—, —S(O)2—, —O—, or —N(R5)—, then U is not a bond; and R1, R2, R3, R4, R5, R6, and R7 are as defined in the specification; and pharmaceutical compositions comprising the compounds of formula 1.

Abstract: Provided are a method, system, and article of manufacture for receiving an initial request from a first device to a second device. A response to the initial request is received from the second device to the first device. Each response and request received from the first device to the second device is processed by accessing the response or request from a packet encoded using a first communication protocol; generating a packet including the accessed response or request into a packet encoded using a second communication protocol; and transmitting the generated packet to the second device. Each response and request received from the second device to the first device is processed by accessing the response or request from a packet encoded using the second communication protocol; generating a packet including the accessed response or request into a packet encoded using the first communication protocol; and transmitting the generated packet to the second device.

Abstract: Low molecular weight graft copolymer comprising a synthetic component formed from at least one or more olefinically unsaturated carboxylic acid monomers or salts thereof, and a natural component formed from a hydroxyl-containing natural moiety. The number average molecular weight of the graft copolymer is about 100,000 or less, and the weight percent of the natural component in the graft copolymer is about 50 wt % or greater based on total weight of the graft copolymer. Processes for preparing such graft copolymers are also disclosed.

Abstract: Disclosed are compounds of the formula I or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein W is a bond, —C(?S)—, —S(O)—, —S(O)2—, —C(?O)—, —O—, —C(R6)(R7)—, —N(R5)— or —C(?N(R5))—; X is —O—, —N(R5)— or —C(R6)(R7)—; provided that when X is —O—, U is not —O—, —S(O)—, —S(O)2—, —C(?O)— or —C(?NR5)—; U is a bond, —S(O)—, —S(O)2—, —C(O)—, —O—, —P(O)(OR15)—, —C(?NR5)—, —(C(R6)(R7))b— or —N(R5)—; wherein b is 1 or 2; provided that when W is —S(O)—, —S(O)2—, —O—, or —N(R5)—, U is not —S(O)—, —S(O)2—, —O—, or —N(R5)—; provided that when X is —N(R5)— and W is —S(O)—, —S(O)2—, —O—, or —N(R5)—, then U is not a bond; and R1, R2, R3, R4, R5, R6, and R7 are as defined in the specification; and pharmaceutical compositions comprising the compounds of formula I.

Abstract: Disclosed are compounds of the formula I or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein U, W, A, R, R1, R2, R6a and R7, are as defined in the specification; and pharmaceutical compositions comprising the compounds of formula I. Also disclosed is the method of inhibiting aspartyl protease, and in particular, the methods of treating cardiovascular diseases, cognitive and neurodegenerative diseases. Also disclosed are methods of treating cognitive or neurodegenerative diseases using the compounds of formula I in combination with a cholinesterase inhibitor or a muscarinic m1 agonist or m2 antagonist.

Abstract: The process, apparatus, and system estimate the size of a data block in a data buffer to efficiently recover the data block to the memory of a computer. The data block resides in a data buffer prior to being written to a destination medium. If the data block cannot be written to the destination medium, the process, apparatus, and system create a data block size estimate. The data block size estimate may be based on the size of the largest data block in the data buffer. Alternately, the data block size estimate may be based on the size of a data block in the memory of the computer. The computer reserves a memory space proportional to the data block size estimate and recovers the data block to the memory space.

Abstract: Disclosed are compounds of the formula I or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein W is a bond, —C(?S)—, —S(O)—, —S(O)2—, —C(?O)—, —O—, —C(R6)(R7)—, —N(R5)— or —C(?N(R5))—; X is —O—, —N(R5)— or —C(R6)(R7)—; provided that when X is —O—, U is not —O—, —S(O)—, —S(O)2—, —C(?O)— or —C(?NR5)—; U is a bond, —S(O)—, —S(O)2—, —C(O)—, —O—, —P(O)(OR15)—, —C(?NR5)—, —(C(R6)(R7))b— or —N(R5)—; wherein b is 1 or 2; provided that when W is —S(O)—, —S(O)2—, —O—, or —N(R5)—, U is not —S(O)—, —S(O)2—, —O—, or —N(R5)—; provided that when X is —N(R5)— and W is —S(O)—, —S(O)2—, —O—, or —N(R5)—, then U is not a bond; and R1, R2, R3, R4, R5, R6, and R7 are as defined in the specification; and pharmaceutical compositions comprising the compounds of formula I.

Abstract: Disclosed are compounds of the formula or a pharmaceutically acceptable salt or solvate thereof, wherein R1 is R is —C(O)—N(R27)(R28) or and the remaining variables are as defined in the specification. Also disclosed are pharmaceutical compositions comprising the compounds of formula I. Also disclosed are methods of treating cognitive or neurodegenerative diseases such as Alzheimer's disease. Also disclosed are pharmaceutical compositions and methods of treating cognitive or neurodegenerative diseases comprising the compounds of formula I in combination with a ?-secretase inhibitor other than those of formula I, an HMG-CoA reductase inhibitor, a gamma-secretase inhibitor, a non-steroidal anti-inflammatory agent, an N-methyl-D-aspartate receptor antagonist, a cholinesterase inhibitor or an anti-amyloid antibody.

Abstract: Disclosed are novel compounds of the formula or a pharmaceutically acceptable salt or solvate thereof, wherein R1 is X is —O—, —C(R14)2— or —N(R)—; Z is —C(R14)2— or —N(R)—; t is 0, 1, 2 or 3; each R and R2 is independently H, alkyl, cycloalkyl, cycloalkylalkyl, aryl, heteroaryl, heterocycloalkyl, arylalkyl, heteroarylalkyl, heterocycloalkylalkyl, alkenyl or alkynyl; each R14 is H, alkyl, alkenyl, alkynyl, halo, —CN, haloalkyl, cycloalkyl, cycloalkylalkyl, aryl, heteroaryl, heterocycloalkyl, arylalkyl, heteroarylalkyl, heterocycloalkylalkyl, —OR35, —N(R24)(R25) or —SR35; R41 is alkyl, cycloalkyl, —SO2(alkyl), —C(O)-alkyl, —C(O)-cycloalkyl or -alkyl-NH—C(O)CH3; and the remaining variables are as defined in the specification. Also disclosed are pharmaceutical compositions comprising the compounds of formula I and methods of treating cognitive or neurodegenerative diseases with compounds of formula I.