Patents by Inventor Tiina Nakari-Setala
Tiina Nakari-Setala has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 10072279Abstract: The present invention concerns a method for producing terpenes in fungi comprising the steps of (a) providing a modified terpene biosynthetic gene cluster inside a host cell, wherein one or more of the naturally occurring genes or promoters of the cluster have been replaced, truncated or removed, (b) providing a transcription factor inside the host cell, the transcription factor activating the terpene biosynthetic gene cluster; (c) cultivating said host in conditions allowing the expression of the transcription factor activating the cluster; and optionally (d) recovering the thus produced terpene product.Type: GrantFiled: May 13, 2013Date of Patent: September 11, 2018Assignee: Teknologian tutkimuskeskus VTT OyInventors: Kirsi Bromann, Mervi Toivari, Tiina Nakari-Setälä, Laura Ruohonen
-
Patent number: 9783793Abstract: The present invention relates to novel polypeptides, or fragments of polypeptides, genes encoding them and means for producing said polypeptides. In detail the invention relates to polypeptides having esterase, suberinase and/or cutinase activity at low pH. This invention relates also to compositions containing the polypeptides and methods of using the polypeptides.Type: GrantFiled: April 11, 2012Date of Patent: October 10, 2017Assignee: Teknologian Tutkimuskeskus VTTInventors: Antti Nyyssola, Hanna Kontkanen, Mari Hakkinen, Ville Pihlajaniemi, Markku Saloheimo, Johanna Buchert, Tiina Nakari-Setala
-
Publication number: 20160194674Abstract: The present invention concerns a method for producing terpenes in fungi comprising the steps of (a) providing a modified terpene biosynthetic gene cluster inside a host cell, wherein one or more of the naturally occurring genes or promoters of the cluster have been replaced, truncated or removed, (b) providing a transcription factor inside the host cell, the transcription factor activating the terpene biosynthetic gene cluster; (c) cultivating said host in conditions allowing the expression of the transcription factor activating the cluster; and optionally (d) recovering the thus produced terpene product.Type: ApplicationFiled: May 13, 2013Publication date: July 7, 2016Applicant: Teknologian tutkimuskeskus VTTInventors: Kirsi Bromann, Mervi Toivari, Tiina Nakari-Setälä, Laura Ruohonen
-
Publication number: 20150225314Abstract: A method for the manufacture of aromatic hydrocarbons, includes allowing at least one olefin to react with at least one hydrogen scavenger at a temperature from 50 to 1000° C., under a pressure from normal atmospheric pressure to 500 bar without an added catalyst, to yield aromatic hydrocarbons.Type: ApplicationFiled: September 13, 2013Publication date: August 13, 2015Inventors: Martta Asikainen, Olli Aaltonen, Ali Harlin, Tiina Nakari-Setala
-
Publication number: 20140234921Abstract: The present invention relates to novel polypeptides, or fragments of polypeptides, genes encoding them and means for producing said polypeptides. In detail the invention relates to polypeptides having esterase, suberinase and/or cutinase activity at low pH. This invention relates also to compositions containing the polypeptides and methods of using the polypeptides.Type: ApplicationFiled: April 11, 2012Publication date: August 21, 2014Applicant: TEKNOLOGIAN TUTKIMUSKESKUS VTTInventors: Antti Nyyssola, Hanna Kontkanen, Mari Hakkinen, Ville Pihlajaniemi, Markku Saloheimo, Johanna Buchert, Tiina Nakari-Setala
-
Publication number: 20140045238Abstract: The present invention relates to a method for producing terpenes in fungi, wherein a terpene biosynthetic gene cluster having terpene biosynthetic genes and regulatory regions operably linked to said genes is activated. The invention relates also to a terpene biosynthetic gene cluster and regulatory regions of such terpene biosynthetic gene cluster usable is production of terpenes, use of regulator for regulating the terpene production and use of Aspergillus nidulans FGSC A4 for producing terpenes. The method of invention provides higher yields of enriched terpene product without essential amount of side-products.Type: ApplicationFiled: November 14, 2011Publication date: February 13, 2014Applicant: TEKNOLOGIAN TUTKIMUSKESKUS VTTInventors: Kirsi Bromann, Tiina Nakari-Setala, Laura Ruohonen, Mervi Toivari, Merja Penttila
-
Patent number: 8546115Abstract: The present invention relates to polyesterases having cutinase and/or suberinase activity obtainable from Coprinus and Trichoderma. The invention further relates to a method for producing the polyesterases, and to polynucleotides, vectors and host cells used therein. The enzymes are useful in hydrolysing cutin, suberin and other polyesters for example in treating agricultural or food raw materials, or wood raw materials, pulp and paper products and waste, and in modifying polyester fibers, or in laundry and dish applications.Type: GrantFiled: July 8, 2008Date of Patent: October 1, 2013Assignee: Valtion Teknillinen TutkimuskeskusInventors: Johanna Buchert, Tiina Nakari-Setälä, Pasi Halonen, Hanna Kontkanen, Ann Westerholm-Parvinen, Marjaana Rättö
-
Publication number: 20100209985Abstract: The present invention relates to polyesterases having cutinase and/or suberinase activity obtainable from Coprinus and Trichoderma. The invention further relates to a method for producing the polyesterases, and to polynucleotides, vectors and host cells used therein. The enzymes are useful in hydrolysing cutin, suberin and other polyesters for example in treating agricultural or food raw materials, or wood raw materials, pulp and paper products and waste, and in modifying polyester fibers, or in laundry and dish applications.Type: ApplicationFiled: July 8, 2007Publication date: August 19, 2010Applicant: Valtion Teknillinen TutkimuskeskusInventors: Johanna Buchert, Tiina Nakari-Setälä, Pasi Halonen, Hanna Kontkanen, Ann Westerholm-Parvinen, Marjaana Rättö
-
Publication number: 20090221039Abstract: The invention relates to fusion proteins including at least a swollenin and at least a plant cell-wall degrading enzyme, the swollenin, and plant cell-wall degrading enzyme, being recombinant proteins corresponding to native proteins in fungi, or mutated forms thereof. The invention also relates to the use of fusion proteins as defined above, for carrying out processes of plant cell-wall degradation in the frame of the preparation, from plants or vegetal by-products, of compounds of interest located in plant cell-wall, or in the frame of the bleaching of pulp and paper, or for biofuel production, or food industries.Type: ApplicationFiled: April 2, 2007Publication date: September 3, 2009Applicants: Institut Francias Du Petrole, VTT Technical Research Centre of Finland, Institute National De La Recherche Agronomique, Universite De ProvenceInventors: Eric Record, Anthony Levasseur, Markku Soloheimo, David Navarro, Martina Andgerg-Blomster, Frederic Monot, Tiina Nakari-Setala, Marcel Asther
-
Patent number: 7338779Abstract: This invention relates to a method for decreasing the foam formation during cultivation of a microorganism and to a method for producing an enhanced amount of a product of interest. The method comprises that the microorganism is modified in such a way that the microorganism does not produce an essential amount of at least one of the proteins, polypeptides or peptides associated with foam formation during cultivation of the unmodified microorganism. In particular the method comprises that the microorganism is modified not to produce an essential amount of amphipathic or hydrophobic proteins, polypeptides or peptides.Type: GrantFiled: August 21, 2000Date of Patent: March 4, 2008Assignee: Valtion Teknillinen TutkimuskeskusInventors: Tiina Nakari-Setälä, Merja Penttilä, Michael Bailey, Maija Tenkanen
-
Patent number: 7335492Abstract: The present invention relates to isolation and purification of protein in aqueous two-phase systems (ATPS). Specifically, the invention provides processes for partitioning of proteins of interest in ATPS by fusing said proteins to targeting proteins which have the ability of carrying said protein into one of the phases.Type: GrantFiled: October 19, 2005Date of Patent: February 26, 2008Assignee: Valtion Teknillinen TutkimuskeskusInventors: Merja Penttilä, Tiina Nakari-Setälä, Richard Fagerström, Klaus Selber, Maria-Regina Kula, Markus Linder, Folke Tjerneld
-
Patent number: 7060669Abstract: The present invention relates to isolation and purification of proteins in aqueous two-phase systems (ATPS). Specifically the invention provides processes for partitioning of proteins of interest in ATPS by fusing said proteins to targeting proteins which have the ability of carrying said protein into one of the phases.Type: GrantFiled: March 24, 2000Date of Patent: June 13, 2006Assignee: Valtion Teknillinen TutkimuskeskusInventors: Merja Penttilä, Tiina Nakari-Setälä, Richard Fagerström, Klaus Selber, Maria-Regina Kula, Markus Linder, Folke Tjerneld
-
Patent number: 7041464Abstract: The invention relates to a method for determining a gushing factor for a beverage, in which method the quantity of hydrophobin is determined from the raw material of the beverage and/or from the beverage. The hydrophobin determination is performed immunologically using an immunological reaction between a hydrophobin antigen and an antibody.Type: GrantFiled: August 18, 2004Date of Patent: May 9, 2006Assignee: Panimolaboratorio-BryggerilaboratoriumInventors: Auli Haikara, Tuija Kleemola, Tiina Nakari-Setälä, Merja Penttilä
-
Publication number: 20060084164Abstract: The present invention relates to isolation and purification of protein in aqueous two-phase systems (ATPS). Specifically, the invention provides processes for partitioning of proteins of interest in ATPS by fusing said proteins to targeting proteins which have the ability of carrying said protein into one of the phases.Type: ApplicationFiled: October 19, 2005Publication date: April 20, 2006Inventors: Merja Penttila, Tiina Nakari-Setala, Richard Fagerstrom, Klaus Selber, Maria-Regina Kula, Markus Linder, Folke Tjerneld
-
Publication number: 20050014204Abstract: The invention relates to a method for determining a gushing factor for a beverage, in which method the quantity of hydrophobin is determined from the raw material of the beverage and/or from the beverage. The hydrophobin determination is performed immunologically using an immunological reaction between a hydrophobin antigen and an antibody.Type: ApplicationFiled: August 18, 2004Publication date: January 20, 2005Inventors: Auli Haikara, Tuija Sarlin, Tiina Nakari-Setala, Merja Penttila
-
Publication number: 20030148400Abstract: The invention relates to a method for determining a gushing factor for a beverage, in which method the quantity of hydrophobin is determined from the raw material of the beverage and/or from the beverage. The hydrophobin determination is performed immunologically using an immunological reaction between a hydrophobin antigen and an antibody.Type: ApplicationFiled: December 4, 2002Publication date: August 7, 2003Inventors: Auli Haikara, Tuija Sarlin, Tiina Nakari-Setala, Merja Penttila