Patents by Inventor Timothy D. Osslund

Timothy D. Osslund has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • High concentration antibody formulations
    Patent number: 10064946
    Abstract: Discloses herein are high concentration antibody formulations comprising an anti-sclerostin immunoglobulin and an acetate salt and/or an acetate buffer and methods of use.
    Type: Grant
    Filed: May 2, 2016
    Date of Patent: September 4, 2018
    Assignee: AMGEN INC.
    Inventor: Timothy D. Osslund
  • Sclerostin antibody crystals and formulations thereof
    Patent number: 9617333
    Abstract: Described herein are anti-sclerostin antibody crystals, methods of making such antibody crystals and formulations comprising the antibody crystals.
    Type: Grant
    Filed: August 21, 2015
    Date of Patent: April 11, 2017
    Assignee: AMGEN INC.
    Inventors: Christi L. Clogston, Twinkle R. Christian, Timothy D. Osslund, Elisabeth Freeman
  • High Concentration Antibody Formulations
    Publication number: 20160235849
    Abstract: Discloses herein are high concentration antibody formulations comprising an anti-sclerostin immunoglobulin and an acetate salt and/or an acetate buffer and methods of use.
    Type: Application
    Filed: May 2, 2016
    Publication date: August 18, 2016
    Applicant: AMGEN INC.
    Inventor: Timothy D. Osslund
  • SCLEROSTIN ANTIBODY CRYSTALS AND FORMULATIONS THEREOF
    Publication number: 20160083460
    Abstract: Described herein are anti-sclerostin antibody crystals, methods of making such antibody crystals and formulations comprising the antibody crystals.
    Type: Application
    Filed: August 21, 2015
    Publication date: March 24, 2016
    Inventors: Christi L. Clogston, Twinkle R. Christian, Timothy D. Osslund, Elisabeth Freeman
  • SCLEROSTIN ANTIBODY CRYSTALS AND FORMULATIONS THEREOF
    Publication number: 20140105909
    Abstract: Described herein are anti-sclerostin antibody crystals, methods of making such antibody crystals and formulations comprising the antibody crystals.
    Type: Application
    Filed: March 23, 2012
    Publication date: April 17, 2014
    Applicant: AMGEN INC.
    Inventors: Christi L. Clogston, Twinkle L. Christian, Timothy D. Osslund, Elisabeth Freeman
  • Modified G-CSF polypeptide
    Patent number: 8058398
    Abstract: The present invention relates to granulocyte colony-stimulating factor (“G-CSF”) hybrid molecules which retain the internal core helices of G-CSF. Also provided are pharmaceutical compositions containing hybrid molecules.
    Type: Grant
    Filed: April 25, 2005
    Date of Patent: November 15, 2011
    Assignee: Amgen Inc.
    Inventor: Timothy D. Osslund
  • G-CSF analog compositions and methods
    Patent number: 7381804
    Abstract: The present invention relates to granulocyte colony-stimulating factor (“G-CSF”) hybrid molecules which retain the internal core helices of G-CSF. Also provided are pharmaceutical compositions containing hybrid molecules.
    Type: Grant
    Filed: December 20, 2001
    Date of Patent: June 3, 2008
    Assignee: Amgen Inc.
    Inventor: Timothy D. Osslund
  • Crystals of etanercept and methods of making thereof
    Patent number: 7276477
    Abstract: The present invention relates to crystalline etanercept and to methods of making crystalline etanercept; to pharmaceutical compositions comprising crystalline etanercept; and to therapeutic uses of such compositions.
    Type: Grant
    Filed: July 29, 2004
    Date of Patent: October 2, 2007
    Assignee: Amgen Inc.
    Inventors: Timothy D. Osslund, Christi L. Clogston, Shon Lee Crampton, Randal B. Bass
  • G-CSF analog compositions and methods
    Publication number: 20010016191
    Abstract: The present invention relates to granulocyte colony-stimulating factor (“G-CSF”) hybrid molecules which retain the internal core helices of G-CSF. Also provided are pharmaceutical compositions containing hybrid molecules.
    Type: Application
    Filed: January 3, 2001
    Publication date: August 23, 2001
    Applicant: AMGEN INC.
    Inventor: Timothy D. Osslund
  • Computer-based methods and articles of manufacture for preparing G-CSF analogs
    Patent number: 5581476
    Abstract: Provided are computer-based methods for preparing G-CSF analogs involving (a) providing computer expression of the three dimensional structure of a G-CSF molecule wherein the chemical moieties, such as each amino acid residue or each atom of each amino acid residue of the G-CSF molecule are correlated with said structure: (b) selecting from said computer expression a site on a G-CSF molecule for alteration; and (c) preparing a G-CSF molecule having such alteration. Also provided are articles of manufacture associated with such methods.
    Type: Grant
    Filed: January 28, 1993
    Date of Patent: December 3, 1996
    Assignee: Amgen Inc.
    Inventor: Timothy D. Osslund