Patents by Inventor Timothy Darren Eubank

Timothy Darren Eubank has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR STABILIZING HYPOXIA INDUCIBLE FACTOR-2 ALPHA AS A METHOD FOR TREATING CANCER
    Publication number: 20170105981
    Abstract: Disclosed herein is {[5-(3-fluorophenyl)-3-hydroxypyridine-2-carbonyl]-amino} acetic acid and the ester and amide prodrugs thereof, that can stabilize hypoxia inducible factor-2 alpha (HIF-2?) and thereby provide a method for treating cancer. Further disclosed are compositions which comprise {[5-(3-fluorophenyl)-3-hydroxypyridine-2-carbonyl]-amino} acetic acid and/or a prodrug thereof which can be used to treat cancer.
    Type: Application
    Filed: May 13, 2016
    Publication date: April 20, 2017
    Applicants: The Ohio State Innovation Foundation, Akebia Therapeutics, Inc.
    Inventors: Clay B. Marsh, Timothy Darren Eubank, Julie Michelle Roda, Robert Shalwitz
  • COMPOSITIONS AND METHODS FOR MODULATING DNA METHYLATION
    Publication number: 20160199434
    Abstract: Disclosed herein are compositions and methods for modulating DNA methylation of one or more gene promoters, treating a subject diagnosed with or suspected of having a disease or disorder characterized by DNA hypermethylation, decreasing c-myc expression, increasing desmoplakin expression, and inhibiting metastases. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: August 15, 2014
    Publication date: July 14, 2016
    Applicant: Ohio State Innovation Foundation
    Inventors: Timothy Darren Eubank, Clay Braden Marsh, Duaa Dakhlallah
  • METHODS FOR STABILIZING HYPOXIA INDUCIBLE FACTOR-2 ALPHA AS A METHOD FOR TREATING CANCER
    Publication number: 20120329836
    Abstract: Disclosed herein is {[5-(3-fluorophenyl)-3-hydroxypyridine-2-carbonyl]-amino}acetic acid and the ester and amide prodrugs thereof, that can stabilize hypoxia inducible factor-2 alpha (HIF-2?) and thereby provide a method for treating cancer. Further disclosed are compositions which comprise {[5-(3-fluorophenyl)-3-hydroxypyridine-2-carbonyl]-amino}acetic acid and/or a prodrug thereof which can be used to treat cancer.
    Type: Application
    Filed: June 5, 2012
    Publication date: December 27, 2012
    Applicant: The Ohio State University
    Inventors: Clay B. Marsh, Timothy Darren Eubank, Julie Michelle Rhoda, Joseph H. Gardner, Robert Shalwitz