Patents by Inventor Timothy F. Jamison

Timothy F. Jamison has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYSTEMS AND METHODS FOR SYNTHESIZING CHEMICAL PRODUCTS, INCLUDING ACTIVE PHARMACEUTICAL INGREDIENTS
    Publication number: 20230201787
    Abstract: Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients, are provided. Certain of the systems and methods described herein are capable of manufacturing multiple chemical products without the need to fluidically connect or disconnect unit operations when switching from one making chemical product to making another chemical product.
    Type: Application
    Filed: December 21, 2022
    Publication date: June 29, 2023
    Applicant: Massachusetts Institute of Technology
    Inventors: Klavs F. Jensen, Timothy F. Jamison, Allan Stuart Myerson, Jean-Christophe M. Monbaliu, Mohsen Behnam, Shin Yee Wong, Nopphon Weeranoppanant, Eve Marie Revalor, Torsten Stelzer, Jie Chen, Andrea Adamo, David R. Snead, Ping Zhang
  • Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients
    Patent number: 11565230
    Abstract: Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients, are provided. Certain of the systems and methods described herein are capable of manufacturing multiple chemical products without the need to fluidically connect or disconnect unit operations when switching from one making chemical product to making another chemical product.
    Type: Grant
    Filed: August 10, 2020
    Date of Patent: January 31, 2023
    Assignee: Massachusetts Institute of Technology
    Inventors: Klavs F. Jensen, Timothy F. Jamison, Allan S. Myerson, Jean-Christophe M. Monbaliu, Mohsen Behnam, Shin Yee Wong, Nopphon Weeranoppanant, Eve Marie Revalor, Torsten Stelzer, Jie Chen, Andrea Adamo, David R. Snead, Ping Zhang
  • Reconfigurable multi-step chemical synthesis system and related components and methods
    Patent number: 11185839
    Abstract: The instant disclosure is related to fluidic distributors, fluidic systems, and associated methods and articles. Certain embodiments are related to fluidic distributors that comprise bays including fluidic connections with relative positions that substantially correspond to each other. In some embodiments, a fluidic distributor may comprise bays with electrical interfaces with relative positions that substantially correspond to each other.
    Type: Grant
    Filed: May 2, 2017
    Date of Patent: November 30, 2021
    Assignee: Massachusetts Institute of Technology
    Inventors: Andrea Adamo, Dale Arlington Thomas, III, Klavs F. Jensen, Timothy F. Jamison, Aaron A. Bedermann, Kosisochukwu C. Aroh
  • SYSTEMS AND METHODS FOR SYNTHESIZING CHEMICAL PRODUCTS, INCLUDING ACTIVE PHARMACEUTICAL INGREDIENTS
    Publication number: 20200368710
    Abstract: Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients, are provided. Certain of the systems and methods described herein are capable of manufacturing multiple chemical products without the need to fluidically connect or disconnect unit operations when switching from one making chemical product to making another chemical product.
    Type: Application
    Filed: August 10, 2020
    Publication date: November 26, 2020
    Applicant: Massachusetts Institute of Technology
    Inventors: Klavs F. Jensen, Timothy F. Jamison, Allan S. Myerson, Jean-Christophe M. Monbaliu, Mohsen Behnam, Shin Yee Wong, Nopphon Weeranoppanant, Eve Marie Revalor, Torsten Stelzer, Jie Chen, Andrea Adamo, David R. Snead, Ping Zhang
  • Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients
    Patent number: 10780410
    Abstract: Systems and methods for synthesizing chemical products, including active pharmaceutical ingredients, are provided. Certain of the systems and methods described herein are capable of manufacturing multiple chemical products without the need to fluidically connect or disconnect unit operations when switching from one making chemical product to making another chemical product.
    Type: Grant
    Filed: August 14, 2015
    Date of Patent: September 22, 2020
    Assignee: Massachusetts Institute of Technology
    Inventors: Klavs F. Jensen, Timothy F. Jamison, Allan S. Myerson, Jean-Christophe M. Monbaliu, Mohsen Behnam, Shin Yee Wong, Nopphon Weeranoppanant, Eve Marie Revalor, Torsten Stelzer, Jie Chen, Andrea Adamo, David R. Snead, Ping Zhang
  • RECONFIGURABLE MULTI-STEP CHEMICAL SYNTHESIS SYSTEM AND RELATED COMPONENTS AND METHODS
    Publication number: 20190126229
    Abstract: The instant disclosure is related to fluidic distributors, fluidic systems, and associated methods and articles. Certain embodiments are related to fluidic distributors that comprise bays including fluidic connections with relative positions that substantially correspond to each other. In some embodiments, a fluidic distributor may comprise bays with electrical interfaces with relative positions that substantially correspond to each other.
    Type: Application
    Filed: May 2, 2017
    Publication date: May 2, 2019
    Applicant: Massachusetts Institute of Technology
    Inventors: Andrea Adamo, Dale Arlington Thomas, III, Klavs F. Jensen, Timothy F. Jamison, Aaron A. Bedermann, Kosisochukwu C. Aroh
  • NICKEL PRE-CATALYSTS AND RELATED COMPOSITIONS AND METHODS
    Publication number: 20160376293
    Abstract: Described herein are nickel pre-catalysts and related compositions and methods. The nickel pre-catalysts may be activated to form catalysts which may be utilized in organic reactions.
    Type: Application
    Filed: June 23, 2016
    Publication date: December 29, 2016
    Applicant: Massachusetts Institute of Technology
    Inventors: Timothy F. Jamison, Eric Alan Standley
  • Nickel pre-catalysts and related compositions and methods
    Patent number: 9382281
    Abstract: Described herein are nickel pre-catalysts and related compositions and methods. The nickel pre-catalysts may be activated to form catalysts which may be utilized in organic reactions.
    Type: Grant
    Filed: November 7, 2014
    Date of Patent: July 5, 2016
    Assignee: Massachusetts Institute of Technology
    Inventors: Timothy F. Jamison, Eric Alan Standley
  • Epoxidation catalysts
    Patent number: 9169277
    Abstract: The present invention generally relates to methods for the synthesis of catalysts, including epoxidation catalysts, and related compounds and catalyst compositions. Embodiments described herein may provide efficient processes for providing catalysts (e.g., epoxidation catalysts) in large quantities and using simplified methods.
    Type: Grant
    Filed: February 6, 2014
    Date of Patent: October 27, 2015
    Assignee: Massachusetts Institute of Technology
    Inventors: Timothy F. Jamison, Yutaka Ikeuchi
  • NICKEL PRE-CATALYSTS AND RELATED COMPOSITIONS AND METHODS
    Publication number: 20150141684
    Abstract: Described herein are nickel pre-catalysts and related compositions and methods. The nickel pre-catalysts may be activated to form catalysts which may be utilized in organic reactions.
    Type: Application
    Filed: November 7, 2014
    Publication date: May 21, 2015
    Applicant: Massachusetts Institute of Technology
    Inventors: Timothy F. Jamison, Eric Alan Standley
  • Methods and systems for the formation of cyclic carbonates
    Patent number: 8921580
    Abstract: Described herein are inventive methods for synthesis of cyclic carbonates from CO2 and epoxide. In some embodiments, the methods are carried out in the presence of a catalyst comprising an electrophilic halogen. In some embodiments, the methods are carried out in a flow reactor.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: December 30, 2014
    Assignee: Massachusetts Institute of Technology
    Inventors: Trevor Alan Hatton, Timothy F. Jamison, Jennifer Aiden Kozak, Fritz Simeon, Jie Wu
  • Continuous flow synthesis of amino alcohols using microreactors
    Patent number: 8877930
    Abstract: The present invention provides various methods for the synthesis of chemical species in a microreactor environment. In some cases, reaction products of the present invention may be valuable as intermediates and/or products in pharmaceutical and polymer research. For example, the method may involve the synthesis of amino alcohols within a microchannel. Embodiment described herein may allow for reactions with significantly shorter reaction times and increased efficiency.
    Type: Grant
    Filed: November 4, 2010
    Date of Patent: November 4, 2014
    Assignee: Massachusetts Institute of Technology
    Inventors: Matthew W. Bedore, Nikolay Zaborenko, Klavs F. Jensen, Timothy F. Jamison
  • Ring opening of lactones and lactams
    Patent number: 8779198
    Abstract: The present invention provides a novel process for opening a lactone and/or a lactam ring. More particularly, the present invention provides a process that employs a novel catalyst in the opening of a lactone ring and/or a lactam ring. Additionally, the present invention also provides a novel deprotection process of any protecting group present in either the lactone ring-containing and/or lactam ring-containing compound and/or in the ring-opened product thereof.
    Type: Grant
    Filed: August 11, 2010
    Date of Patent: July 15, 2014
    Assignees: Novartis AG, Massachusetts Institute of Technology
    Inventors: Megan Alene Foley, Timothy F. Jamison, Oljan Repic
  • EPOXIDATION CATALYSTS
    Publication number: 20140155634
    Abstract: The present invention generally relates to methods for the synthesis of catalysts, including epoxidation catalysts, and related compounds and catalyst compositions. Embodiments described herein may provide efficient processes for providing catalysts (e.g., epoxidation catalysts) in large quantities and using simplified methods.
    Type: Application
    Filed: February 6, 2014
    Publication date: June 5, 2014
    Applicant: Massachusetts Institute of Technology
    Inventors: Timothy F. Jamison, Yutaka Ikeuchi
  • Epoxidation catalysts
    Patent number: 8680303
    Abstract: The present invention generally relates to methods for the synthesis of catalysts, including epoxidation catalysts, and related compounds and catalyst compositions. Embodiments described herein may provide efficient processes for providing catalysts (e.g., epoxidation catalysts) in large quantities and using simplified methods.
    Type: Grant
    Filed: February 28, 2011
    Date of Patent: March 25, 2014
    Assignee: Massachusetts Institute of Technology
    Inventors: Timothy F. Jamison, Yutaka Ikeuchi
  • METHODS AND SYSTEMS FOR THE FORMATION OF CYCLIC CARBONATES
    Publication number: 20130310575
    Abstract: Described herein are inventive methods for synthesis of cyclic carbonates from CO2 and epoxide. In some embodiments, the methods are carried out in the presence of a catalyst comprising an electrophilic halogen. In some embodiments, the methods are carried out in a flow reactor.
    Type: Application
    Filed: March 14, 2013
    Publication date: November 21, 2013
    Inventors: Trevor Alan Hatton, Timothy F. Jamison, Jennifer Aiden Kozak, Fritz Simeon, Jie Wu
  • USE OF AZIDES IN SYNTHESIS
    Publication number: 20130225819
    Abstract: Described herein are inventive methods for synthesis of tetrazoles. In some embodiments, the method involves the use of a flow reactor. The methods provided herein are capable at being carried out in short reaction times, with high yields, with minimal side reactions, and/or with minimal chance of explosions caused by the presence of azides.
    Type: Application
    Filed: August 18, 2011
    Publication date: August 29, 2013
    Applicant: Massachusetts Institute of Technology
    Inventors: Timothy F. Jamison, Prakash B. Palde
  • Histone deacetylases, and uses related thereto
    Patent number: 8426592
    Abstract: The present invention concerns the discovery that proteins encoded by a family of genes, termed here HDx-related genes, which are involved in the control of chromatin structure and, thus in transcription and translation. The present invention makes available compositions and methods that can be utilized, for example to control cell proliferation and differentiation in vitro and in vivo.
    Type: Grant
    Filed: August 3, 2012
    Date of Patent: April 23, 2013
    Assignee: President and Fellows of Harvard College
    Inventors: Stuart L. Schreiber, Jack Taunton, Christian A. Hassig, Timothy F. Jamison
  • Histone deacetylases, and uses related thereto
    Patent number: 8399233
    Abstract: The present invention concerns the discovery that proteins encoded by a family of genes, termed here HDx-related genes, which are involved in the control of chromatin structure and, thus in transcription and translation. The present invention makes available compositions and methods that can be utilized, for example to control cell proliferation and differentiation in vitro and in vivo.
    Type: Grant
    Filed: August 16, 2004
    Date of Patent: March 19, 2013
    Assignee: President and Fellows of Harvard College
    Inventors: Stuart L. Schreiber, Jack Taunton, Christian A. Hassig, Timothy F. Jamison
  • Histone deacetylases, and uses related thereto
    Patent number: 8362084
    Abstract: The present invention concerns the discovery that proteins encoded by a family of genes, termed here HDx-related genes, which are involved in the control of chromatin structure and, thus in transcription and translation. The present invention makes available compositions and methods that can be utilized, for example to control cell proliferation and differentiation in vitro and in vivo.
    Type: Grant
    Filed: February 17, 2011
    Date of Patent: January 29, 2013
    Assignee: President and Fellows of Harvard College
    Inventors: Stuart L. Schreiber, Jack Taunton, Christian A. Hassig, Timothy F. Jamison