Abstract: The various examples presented herein are directed to compounds of the formula A-L1-Het1-L2-Cy1 or a pharmaceutical acceptable salt, polymorph, prodrug, solvate or clathrate thereof, wherein: A is cycloalkyl, aryl, arylalkyl or heterocyclyl; Het1 is heterocyclyl containing at least two heteroatoms; Cy1 is a heterocyclyl; L1 is a bond, alkyl, alkenyl or alkynyl linker; L2 is an acyl or alkyl linker; and A and Cy1 are different. The compounds are useful in the treatment of fibrotic diseases, abnormal vascular leak and pathological angiogenesis.

Abstract: The present embodiments provide systems and methods for treating a medical condition. In one embodiment, the system comprises a stent having proximal and distal regions, and further having a delivery state and an expanded state. A therapeutic agent is disposed on a segment of the stent. The stent is disposed around an exterior surface of a core assembly in the delivery state. A coupling assembly releasably secures the proximal region of the stent to the exterior surface of the core assembly. The coupling assembly secures the stent to the core assembly for a predetermined period while the stent is in the expanded state and during release of the therapeutic agent at a target site. The coupling assembly further enables the stent to be disengaged from the core assembly and deployed in a bodily passageway.

Abstract: The present embodiments provide systems and methods for treating a medical condition. In one embodiment, the system comprises a stent having proximal and distal regions, and further having a delivery state and an expanded state. A therapeutic agent is disposed on a segment of the stent. The stent is disposed around an exterior surface of a core assembly in the delivery state. A coupling assembly releasably secures the proximal region of the stent to the exterior surface of the core assembly. The coupling assembly secures the stent to the core assembly for a predetermined period while the stent is in the expanded state and during release of the therapeutic agent at a target site. The coupling assembly further enables the stent to be disengaged from the core assembly and deployed in a bodily passageway.

Abstract: One embodiment of the present invention sets forth a technique for efficiently performing voting operations within a multi-threaded parallel-processing system. A group of related parallel program threads executes within a processor core together in parallel. A new instruction, called a “vote” instruction, is introduced that enables a parallel program thread to post an individual vote within the context of the group of related threads and to receive the result of the vote. In this fashion, the vote instruction advantageously reduces overhead associated with inter-thread communication, thereby improving overall system performance.

Abstract: A method of producing butene from an oxygenate-containing feedstock is described. The oxygenate-containing feedstock is converted to olefins and separated. The C4 isoolefins are then etherified and separated. The normal C4 olefins can be used to produce butadiene.

Abstract: One embodiment of the present invention sets forth a technique for efficiently performing voting operations within a multi-threaded parallel-processing system. A group of related parallel program threads executes within a processor core together in parallel. A new instruction, called a “vote” instruction, is introduced that enables a parallel program thread to post an individual vote within the context of the group of related threads and to receive the result of the vote. In this fashion, the vote instruction advantageously reduces overhead associated with inter-thread communication, thereby improving overall system performance.

Abstract: A method for altering the course of a conflagration involving firing a projectile comprising a powder mixture of oxidant powder and nanosized reductant powder at velocity sufficient for a violent reaction between the oxidant powder and the nanosized reductant powder upon impact of the projectile, and causing impact of the projectile at a location chosen to draw a main fire to a spot fire at such location and thereby change the course of the conflagration, whereby the air near the chosen location is heated to a temperature sufficient to cause a spot fire at such location. The invention also includes a projectile useful for such method and said mixture preferably comprises a metastable intermolecular composite.

Abstract: One embodiment of the present invention sets forth a technique for efficiently performing voting operations within a multi-threaded parallel-processing system. A group of related parallel program threads executes within a processor core together in parallel. A new instruction, called a “vote” instruction, is introduced that enables a parallel program thread to post an individual vote within the context of the group of related threads and to receive the result of the vote. In this fashion, the vote instruction advantageously reduces overhead associated with inter-thread communication, thereby improving overall system performance.

Abstract: One embodiment of the present invention sets forth a technique for efficiently performing voting operations within a multi-threaded parallel-processing system. A group of related parallel program threads executes within a processor core together in parallel. A new instruction, called a “vote” instruction, is introduced that enables a parallel program thread to post an individual vote within the context of the group of related threads and to receive the result of the vote. In this fashion, the vote instruction advantageously reduces overhead associated with inter-thread communication, thereby improving overall system performance.

Abstract: A method for pre-loading a shape memory alloy coil spring wound in a first direction after a shape-setting treatment, the method comprising inverting the coil spring by attaching one end of the coil spring to a core and unwinding it while winding it around the core in a second direction opposite to the first direction.

Abstract: A system comprising one or more sample vessels is provided, the sample vessels comprising a liquid growth medium and a stirrer element, the stirrer element capable of being influenced by a magnetic force, and an incubation and measurement module comprising one or more openings for holding the one or more sample vessels. The incubation and measurement module further comprises at least two drive magnets associated with each of the sample vessels, and a magnet driver adapted to repeatedly move each of the at least two drive magnets toward and away from the surface of the associated sample vessel.

Abstract: An air depolarized battery with an improved sealing member for sealing the air inlet port(s) of the battery before use is disclosed. The sealing member has areas of relatively high and low permeability, with an area of low permeability over at least a portion of an air inlet port. The rate of flow of air through the low permeability area and into the battery can be easily modified to maintain a desired battery open circuit voltage during battery storage to allow activation of the battery within a short time after removal of the sealing member, while minimizing losses in discharge capacity before use.

Abstract: A system and method for detecting a pathogen in a sample is provided, the system capable of measuring the volume of a sample in a container through the use of various measurement technologies, thereby ensuring that a user is aware of volumes not meeting specification and/or allowing correction of results to account for the out-of-specification sample.

Abstract: The present invention relates to methods for detection and evaluation of metabolic activity of eukaryotic and/or prokaryotic cells based upon their ability to consume dissolved oxygen. The methods utilize a luminescence detection system which makes use of the sensitivity of the luminescent emission of certain compounds to the presence of oxygen, which quenches (diminishes) the compound's luminescent emission in a concentration dependent manner. Respiring eukaryotic and/or prokaryotic cells will affect the oxygen concentration of a liquid medium in which they are immersed. Thus, this invention provides a convenient system to gather information on the presence, identification, quantification and cytotoxic activity of eukaryotic and/or prokaryotic cells by determining their effect on the oxygen concentration of the media in which they are present.

Abstract: Various embodiments of a metal-air cell having a tab system that covers an air entry port of the metal-air cell are provided. In one representative embodiment the tab system includes polymer layer and an adhesive layer between the metal-air cell and the polymer layer. The tab system has a loss stiffness of less than 55,000 N/m at 20° C. to 25° C.

Abstract: Systems and techniques for promotion of financial services to consumers are described. In one aspect, a system comprises a database of provider information including identification of affiliated providers, the services offered by the providers and categories of customers served by the providers and incentives offered by the providers, as well as an incentive information database including identification of incentives offered in exchange for selecting affiliated providers, levels of incentives offered and qualification requirements for each incentive and incentive level.

Abstract: A process for cracking a naphtha feedstream to light olefins is presented. The process comprises converting aromatics and naphthenes to paraffins, and separating iso- and normal paraffins using a ring opening reactor and an adsorption separation unit.