Patents by Inventor Timothy G. Lease

Timothy G. Lease has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sulfonamide substituted chroman derivatives
    Patent number: 6903218
    Abstract: This invention related to novel sulfonamide substituted chroman derivatives which are useful in the treatment of beta-3 receptor mediated conditions.
    Type: Grant
    Filed: September 19, 2003
    Date of Patent: June 7, 2005
    Assignee: Bayer Pharmaceuticals Corporation
    Inventors: Gaetan H. Ladouceur, Richard D. Connell, Jeremy Baryza, Ann-Marie Campbell, Timothy G. Lease, James H. Cook
  • Carboxyl substituted chroman derivatives useful as beta 3 adrenoreceptor agonists
    Patent number: 6797714
    Abstract: This invention is related to novel carboxyl substituted chroman derivatives which are useful in the treatment of beta-3 receptor mediated conditions.
    Type: Grant
    Filed: August 21, 2002
    Date of Patent: September 28, 2004
    Assignee: Bayer Pharmaceuticals Corporation
    Inventors: Richard D. Connell, Timothy G. Lease, Jeremy L. Baryza
  • Novel sulfonamide substituted chroman derivatives useful as beta 3 adrenoreceptor agonists
    Publication number: 20040072843
    Abstract: This invention related to novel sulfonamide substituted chroman derivatives which are useful in the treatment of beta-3 receptor mediated conditions.
    Type: Application
    Filed: September 19, 2003
    Publication date: April 15, 2004
    Inventors: Gaetan H. Ladouceur, Richard D. Connell, Jeremy Baryza, Ann-Marie Campbell, Timothy G. Lease, James H. Cook
  • Compounds useful for preparation of Beta-3 adrenoreceptor agonist
    Publication number: 20030073839
    Abstract: This invention related to novel sulfonamide substituted chroman derivatives which are useful in the treatment of beta-3 receptor mediated conditions.
    Type: Application
    Filed: March 7, 2000
    Publication date: April 17, 2003
    Inventors: Gaetan H. Ladouceur, Richard D. Connell, Jeremy Baryza, Anne-Marie Campbell, Timothy G. Lease, James H. Cook
  • Novel carboxyl substituted chroman derivatives useful as beta 3 adrenoreceptor agonists
    Publication number: 20030013705
    Abstract: This invention is related to novel carboxyl substituted chroman derivatives which are useful in the treatment of beta-3 receptor mediated conditions.
    Type: Application
    Filed: August 21, 2002
    Publication date: January 16, 2003
    Inventors: Richard D. Connell, Timothy G. Lease, Jeremy L. Baryza
  • Carboxyl substituted chroman derivatives useful as beta 3 adrenoreceptor agonists
    Patent number: 6469031
    Abstract: This invention is related to novel carboxyl substituted chroman derivatives which are useful in the treatment of beta-3 receptor mediated conditions.
    Type: Grant
    Filed: December 18, 1998
    Date of Patent: October 22, 2002
    Assignee: Bayer Corporation
    Inventors: Richard D. Connell, Timothy G. Lease, Jeremy Baryza
  • Amide derivatives and methods for using the same as selective neuropeptide Y receptor antagonists
    Patent number: 6410792
    Abstract: Amide derivatives and methods of administering the compositions to mammals to treat disorders such as obesity that are mediated by NPY and especially those mediated by NPY via the Y5 receptor.
    Type: Grant
    Filed: April 20, 1999
    Date of Patent: June 25, 2002
    Assignee: Bayer Corporation
    Inventors: Richard D. Connell, Timothy G. Lease, Gaetan H. Ladouceur, Martin H. Osterhout
  • NPY5 receptor antagonists and methods for using same
    Patent number: 6245817
    Abstract: &agr;-alkoxy and &agr;-thioalkoxyamide compositions and methods of administering the compositions to mammals to treat disorders such as obesity that are mediated by NPY and especially those mediated by NPY via the Y5 receptor.
    Type: Grant
    Filed: April 20, 1999
    Date of Patent: June 12, 2001
    Assignee: Bayer Corporation
    Inventors: Richard D. Connell, Timothy G. Lease, Gaetan H. Ladouceur, Martin H. Osterhout
  • Substituted biphenyls
    Patent number: 6218431
    Abstract: Substituted biphenyls having glucagon receptor antagonistic activity. Claimed compounds have the formula wherein R1a and R1b independently represent (C1-C6) alkyl; R2 represents (C1-C10) alkyl or substituted (C1-C10) alkyl wherein the substituents are independently from 1 to 3 of —SR7; R7 represents phenyl, or substituted phenyl wherein the substituents are independently 1-5 of halogen, trifluoromethyl, (C1-C6) alkyl, (C1-C6) alkoxy, nitro, cyano, or hydroxyl; R3 represents substituted (C1-C6) alkyl wherein the substituents are 1-2 hydroxyl groups; G represents a substituent selected from the group consisting of halogen, (C1-C6) alkyl, and OR4 wherein R4 is H or (C1-C6) alkyl; and y is 0 or an integer of 1-3. Pharmaceutical compositions containing such compounds and methods of treatment of glucagon-mediated conditions by administering such compounds are also claimed.
    Type: Grant
    Filed: July 31, 1997
    Date of Patent: April 17, 2001
    Assignees: Bayer Corporation, Bayer Aktiengesellschaft
    Inventors: William R. Schoen, Gaetan H. Ladouceur, James H. Cook, II, Timothy G. Lease, Donald J. Wolanin, Richard H. Kramss, Donald L. Hertzog, Martin H. Osterhout
  • Sulfonamide substituted chroman derivatives useful as beta 3 adrenoreceptor agonists
    Patent number: 6051586
    Abstract: This invention related to novel sulfonamide substituted chroman derivatives which are useful in the treatment of beta-3 receptor mediated conditions.
    Type: Grant
    Filed: November 23, 1998
    Date of Patent: April 18, 2000
    Assignee: Bayer Corporation
    Inventors: Gaetan H. Ladouceur, Richard D. Connell, Jeremy Baryza, Ann-Marie Campbell, Timothy G. Lease, James H. Cook
  • Amide derivatives and methods for using the same as selective neuropeptide Y receptor antagonists
    Patent number: 6048900
    Abstract: Amide derivatives and methods of administering the compositions to mammals to treat disorders such as obesity that are mediated by NPY and especially those mediated by NPY via the Y5 receptor.
    Type: Grant
    Filed: February 13, 1998
    Date of Patent: April 11, 2000
    Assignee: Bayer Corporation
    Inventors: Richard D. Connell, Timothy G. Lease, Gaetan H. Ladouceur, Martin H. Osterhout
  • NPY5 receptor antagonists and methods for using same
    Patent number: 5939462
    Abstract: .alpha.-alkoxy and .alpha.-thioalkoxyamide compositions and methods of administering the compositions to mammals to treat disorders such as obesity that are mediated by NPY and especially those mediated by NPY via the Y5 receptor.
    Type: Grant
    Filed: February 13, 1998
    Date of Patent: August 17, 1999
    Assignee: Bayer Corporation
    Inventors: Richard D. Connell, Timothy G. Lease, Gaetan H. Ladouceur, Martin H. Osterhout