Abstract: Provided herein are methods of identifying genomic region(s) predictive of an outcome of treatment with a cell therapy and/or of a phenotype of function of the cells. In some embodiments, the methods include epigenetic and/or epigenomic analyses of the cells in connection with methods for preparing engineered cells for cell therapy and/or predicting response to a cell therapy, e.g., engineered cells for cell therapy. In some embodiments, the methods include steps to assess, characterize and analyze changes or modifications in an epigenetic property of gene region or regions, such as chromatin accessibility, nucleosome occupancy, histone modification, spatial chromosomal conformation, transcription factor occupancy and/or DNA methylation. In some embodiments, the epigenetic and/or epigenomic analysis includes determining the epigenetic properties of a cell, e.g., an engineered cell for cell therapy.

Abstract: In association with a computer system, a method and system for providing an interface for establishing connections with financial institution to utilize on-line services. An application program sends a request to a branding server to look up information related to a particular financial institution. The branding server executes the request and, if the branding server contains information relating to the method of connection with identified financial institution, the branding server sends the information to the application program. The application program then loads an appropriate driver corresponding to the method of connection as determined by the branding server. If the method of connection is open financial connectivity (OFC), then the application loads a flexible driver (the OFC driver) which causes the application program to request the business rules of the particular financial institution from the financial institution's server.