Patents by Inventor Timothy J. Kurtti

Timothy J. Kurtti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of diagnosing human granulocytic Ehrlichiosis
    Patent number: 5928879
    Abstract: Methods for the in vitro cultivation, propagation, and production of antigens of Ehrlichia phagocytophila genogroup granulocytic Ehrlichiae, including Ehrlichia equi, in Ixodes scapularis tick cell culture and in human HL60 promyelocytic leukemia cell culture.
    Type: Grant
    Filed: August 25, 1995
    Date of Patent: July 27, 1999
    Assignees: The Regents of the University of Minnesota, The Regents of the University of California, University of Maryland at Baltimore
    Inventors: J. Stephen Dumler, Ulrike G. Munderloh, John Madigan, Jesse Goodman, Timothy J. Kurtti
  • Method of growing rickettsiae in Ixodes scapularis tick cell culture and preparing antigens and vaccines of rickettsiae
    Patent number: 5869335
    Abstract: The invention is directed to methods of culturing rickettsiae in Ixodes scapularis cell lines. The methods of the invention provide for culture of microorganisms such as Anaplasma marginale, Ehrlichia canis, and Rickettsia rickettsii. A method of the invention involves incubating a rickettsia with an Ixodes scapularis tick cell culture in a culture medium under reduced oxygen and increased CO.sub.2 at a sufficient temperature until growth of the rickettsia is detected. The culture medium comprises a medium suitable for the growth of invertebrate cells supplemented with an organic buffer. The cell culture method can be used in large scale production of rickettsia containing products useful in diagnostic assays and vaccine preparations.
    Type: Grant
    Filed: August 25, 1995
    Date of Patent: February 9, 1999
    Assignee: Regents of the University of Minnesota
    Inventors: Ulrike G. Munderloh, Timothy J. Kurtti, Katherine M. Kocan, Edmour F. Blouin, Sidney A. Ewing