Patents by Inventor Timothy J. Mitchison

Timothy J. Mitchison has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Small molecules used to increase cell death
    Publication number: 20040266846
    Abstract: The invention features methods for increasing cell death. The invention also features compounds used to increase cell death. The invention further features methods for identifying compounds that increase cell death.
    Type: Application
    Filed: March 16, 2004
    Publication date: December 30, 2004
    Inventors: Junying Yuan, Alexei Degterev, Timothy J. Mitchison
  • Small molecule inhibitors of necrosis
    Patent number: 6756394
    Abstract: The invention features methods for decreasing necrosis. The invention also features methods for treating a subject with a condition in which necrosis occurs. The invention further features chemical compounds used to decrease necrosis.
    Type: Grant
    Filed: October 13, 2000
    Date of Patent: June 29, 2004
    Assignee: President and Fellow of Harvard College
    Inventors: Junying Yuan, Alexei Degterev, Timothy J. Mitchison
  • Dihydropyrancarboxamides and uses thereof
    Publication number: 20040059138
    Abstract: The present invention provides novel dihydropyrancarboxamide compounds of formula (I): 1
    Type: Application
    Filed: August 27, 2003
    Publication date: March 25, 2004
    Inventors: Stuart L. Schreiber, Robert A. Stavenger, Timothy J. Mitchison, Zoltan Maliga
  • Small molecules used to increase cell death
    Patent number: 6706766
    Abstract: The invention features methods for increasing cell death. The invention also features compounds used to increase cell death. The invention further features methods for identifying compounds that increase cell death.
    Type: Grant
    Filed: July 16, 2002
    Date of Patent: March 16, 2004
    Assignee: President and Fellows of Harvard College
    Inventors: Junying Yuan, Alexei Degterev, Timothy J. Mitchison
  • Small molecules used to increase cell death
    Publication number: 20030083386
    Abstract: The invention features methods for increasing cell death. The invention also features compounds used to increase cell death. The invention further features methods for identifying compounds that increase cell death.
    Type: Application
    Filed: July 16, 2002
    Publication date: May 1, 2003
    Inventors: Junying Yuan, Alexei Degterev, Timothy J. Mitchison
  • Detecting structural or synthetic information about chemical compounds
    Patent number: 6541203
    Abstract: The present invention provides an improved system for the rapid and non-destructive identification of chemical compounds attached to solid supports. In general, the invention provides an identification unit comprising a tag attached to the solid support and a binding partner that interacts specifically and detectably with he tag. In preferred embodiments, the identification unit incorporates the advantages of chemically robust tags and a decoding technique capable of amplification for easy detection and analysis. The present invention further provides a kit comprising a collection of tags capable of attachment to a support and binding partners capable of binding selectively and detectably to the tags, to generate an identification unit for the facile determination of the structure of a compound of interest by determining the reaction history and/or structural characteristics of the compounds that are encoded by the identification unit.
    Type: Grant
    Filed: November 23, 1999
    Date of Patent: April 1, 2003
    Assignee: President and Fellows of Harvard College
    Inventor: Timothy J. Mitchison
  • DETECTING STRUCTURAL OR SYNTHETIC INFORMATION ABOUT CHEMICAL COMPOUNDS
    Publication number: 20020006614
    Abstract: The present invention provides an improved system for the rapid and non-destructive identification of chemical compounds attached to solid supports. In general, the invention provides an identification unit comprising a tag attached to the solid support and a binding partner that interacts specifically and detectably with he tag. In preferred embodiments, the identification unit incorporates the advantages of chemically robust tags and a decoding technique capable of amplification for easy detection and analysis. The present invention further provides a kit comprising a collection of tags capable of attachment to a support and binding partners capable of binding selectively and detectably to the tags, to generate an identification unit for the facile determination of the structure of a compound of interest by determining the reaction history and/or structural characteristics of the compounds that are encoded by the identification unit.
    Type: Application
    Filed: November 23, 1999
    Publication date: January 17, 2002
    Inventor: TIMOTHY J. MITCHISON
  • Thyroid hormone analogues and methods for their preparation
    Patent number: 6107517
    Abstract: Thyroid hormone analogues are disclosed. Methods of using such analogues and pharmaceutical compositions containing them are also disclosed, as are novel procedures for their preparation.
    Type: Grant
    Filed: June 30, 1999
    Date of Patent: August 22, 2000
    Assignee: The Regents of the University of California
    Inventors: Thomas S. Scanlan, Hikari A.I. Yoshihara, Grazia Chiellini, Timothy J. Mitchison