Patents by Inventor Timothy L. Vail

Timothy L. Vail has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microsensor material and methods for analyte detection
    Patent number: 8828733
    Abstract: The compositions and methods relate to an organic polymer-inorganic particle sensor material for detecting analytes. Interactions between the polymer and the particles are affected by the presence of analyte, which displaces the polymer and increases its free volume. This change in free volume can be detected, e.g., using an embedded piezoresistive microcantilever (EPM) sensor. Analytes that can be detected include noxious substances, such as hydrogen cyanide gas and carbon monoxide.
    Type: Grant
    Filed: January 18, 2008
    Date of Patent: September 9, 2014
    Assignees: Cantimer, Inc., Arizona Board Of Regents For And On Behalf Of Northern Arizona University
    Inventors: Timothy L. Porter, Ray Stewart, Timothy L. Vail
  • In vivo biofilm infection diagnosis and treatment
    Patent number: 8697375
    Abstract: The present invention relates to a method for in vivo detection of a biofilm infection residing in a mammal, the method comprising (i) administering to the mammal a diagnostic-effective amount of a biofilm-specific probe, wherein the probe comprises a bio film-targeting moiety and a paramagnetic nanoparticle core; and (ii) imaging the mammal to detect the presence of the biofilm infection by observing the mammal using a magnetic resonance diagnostic technique after the biofilm-specific probe has been provided sufficient time to selectively bind to the bio film infection that may be present in the mammal. The invention also relates to methods of treatment of a bio film infection, and compositions and kits useful in the detection and/or treatment of bio film infections.
    Type: Grant
    Filed: September 2, 2009
    Date of Patent: April 15, 2014
    Assignees: University of Maryland, Baltimore, Arizona Board of Regents A Body Corporate of the State of Arizona
    Inventors: Mark E. Shirtliff, Rebecca A. Brady, Jeffrey G. Leid, Timothy L. Vail, Jennifer M. Kofonow
  • RAPID MULTIPLEX LATERAL FLOW ASSAY DEVICE
    Publication number: 20130280698
    Abstract: Disclosed herein are devices, systems and methods for simultaneously conducting multiple assays on a liquid sample for the presence of, and/or quantification of, analytes in the liquid sample. The device, which is referred to herein as a multi-assay cartridge or multi-strip assay cartridge (MSC), may be used in a system comprised of the cartridge and a reading device or reader for reading the assays in the cartridge.
    Type: Application
    Filed: April 24, 2013
    Publication date: October 24, 2013
    Inventors: Catherine R. Propper, John T. Tester, Timothy L. Vail, Niranjan Venkatraman
  • Methods and devices for the detection of biofilm
    Patent number: 8541006
    Abstract: The present invention provides methods and kits for biofilm detection.
    Type: Grant
    Filed: July 30, 2008
    Date of Patent: September 24, 2013
    Assignees: University of Maryland, Baltimore, The Arizona Board of Regents, a body corporate acting for and on behalf of Northern Arizona University
    Inventors: Jeffrey G. Leid, Timothy L. Vail, Jennifer M. Kofonow, Mark E. Shirtliff, Rebecca A. Brady
  • In Vivo Biofilm Infection Diagnosis and Treatment
    Publication number: 20110171123
    Abstract: The present invention relates to a method for in vivo detection of a biofilm infection residing in a mammal, the method comprising (i) administering to the mammal a diagnostic-effective amount of a biofilm-specific probe, wherein the probe comprises a bio film-targeting moiety and a paramagnetic nanoparticle core; and (ii) imaging the mammal to detect the presence of the biofilm infection by observing the mammal using a magnetic resonance diagnostic technique after the biofilm-specific probe has been provided sufficient time to selectively bind to the bio film infection that may be present in the mammal. The invention also relates to methods of treatment of a bio film infection, and compositions and kits useful in the detection and/or treatment of bio film infections.
    Type: Application
    Filed: September 2, 2009
    Publication date: July 14, 2011
    Applicant: University of Maryland, Baltimore
    Inventors: Mark E. Shirtliff, Rebecca A. Brady, Jeffrey G. Leid, Timothy L. Vail, Jennifer M. Kofonow
  • Methods and Devices for the Detection of Biofilm
    Publication number: 20100285496
    Abstract: The present invention provides methods and kits for biofilm detection.
    Type: Application
    Filed: July 30, 2008
    Publication date: November 11, 2010
    Applicant: University of Maryland Baltimore
    Inventors: Jeffrey G. Leid, Timothy L. Vail, Jennifer M. Kofonow, Mark E. Shirtliff, Rebecca A. Brady
  • MICROSENSOR MATERIAL AND METHODS FOR ANALYTE DETECTION
    Publication number: 20100203648
    Abstract: The compositions and methods relate to an organic polymer-inorganic particle sensor material for detecting analytes. Interactions between the polymer and the particles are affected by the presence of analyte, which displaces the polymer and increases its free volume. This change in free volume can be detected, e.g., using an embedded piezoresistive microcantilever (EPM) sensor. Analytes that can be detected include noxious substances, such as hydrogen cyanide gas and carbon monoxide.
    Type: Application
    Filed: January 18, 2008
    Publication date: August 12, 2010
    Inventors: Timothy L. Porter, Ray Stewart, Timothy L. Vail, Michael P. Eastman